SLC5A5 and ERBB2IP

Number of citations of the paper that reports this interaction (PMID 15123239)
9

Data Source:
BioGRID (unspecified method)

		SLC5A5	ERBB2IP
Gene Name		solute carrier family 5 (sodium/iodide cotransporter), member 5	erbb2 interacting protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Plasma Membrane Integral Component Of Membrane Vesicle Extracellular Vesicular Exosome	Basement Membrane Nucleus Nucleoplasm Cytoplasm Plasma Membrane Basal Plasma Membrane Cell Junction Hemidesmosome Nuclear Membrane
	Molecular Function	Sodium:iodide Symporter Activity Iodide Transmembrane Transporter Activity	ErbB-2 Class Receptor Binding Integrin Binding Structural Constituent Of Cytoskeleton Protein Binding
	Biological Process	Thyroid Hormone Generation Transport Ion Transport Iodide Transport Cellular Nitrogen Compound Metabolic Process Sodium Ion Transmembrane Transport Small Molecule Metabolic Process Transmembrane Transport Cellular Response To CAMP Cellular Response To Gonadotropin Stimulus	Protein Targeting Cell Cycle Cell Adhesion Signal Transduction Epidermal Growth Factor Receptor Signaling Pathway Integrin-mediated Signaling Pathway Cell Growth Intermediate Filament Cytoskeleton Organization Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity
Pathways		Organic anion transporters Amine-derived hormones Transport of inorganic cations/anions and amino acids/oligopeptides Thyroxine biosynthesis SLC-mediated transmembrane transport Metabolism of amino acids and derivatives	Signaling by ERBB2
Drugs
Diseases
GWAS
Protein-Protein Interactions		1 interactors: ERBB2IP	62 interactors: ABCA1 ABCC4 ABR ACTN1 ACTN2 ACVR2A ACVR2B AGTR2 APC ARHGEF7 ARVCF ATP2B1 ATP2B2 ATP2B4 BANF1 CASK CDH1 CHUK COPB1 CTNNB1 CTNND1 CTNND2 CTSG DLG4 DST ERBB2 FOXO3 GRIN2B GRIN2C GUCY1A2 ITGB4 KCNA4 KCNA5 LAMB1 LMO1 LMO2 LRRC1 MAP4 MAPK12 MCC MEF2A MPP1 MPP2 MPP3 NOD2 NR2E1 PICK1 PKP4 RAF1 SCN4A SHOC2 SLC5A5 SLC5A6 SLC6A12 SMAD1 SMAD2 SMAD3 SMAD4 SMAD7 STAT3 VIPR2 ZFYVE9
Entrez ID		6528	55914
HPRD ID		03504	06090
Ensembl ID		ENSG00000105641	ENSG00000112851
Uniprot IDs		Q92911	B4DIP2 Q96RT1
PDB IDs			1MFG 1MFL 1N7T 2H3L 2QBW 3CH8
Enriched GO Terms of Interacting Partners?		Basal Protein Localization Establishment Or Maintenance Of Epithelial Cell Apical/basal Polarity Asymmetric Protein Localization Establishment Or Maintenance Of Apical/basal Cell Polarity Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Integrin-mediated Signaling Pathway Cell Growth Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Establishment Or Maintenance Of Cell Polarity	Regulation Of Signaling Response To Stimulus Response To Organic Substance Signaling Cellular Response To Growth Factor Stimulus Cell Communication Response To Growth Factor Cellular Response To Organic Substance Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Signal Transduction Response To Stress Positive Regulation Of Cellular Metabolic Process Cellular Response To Stimulus Positive Regulation Of Cellular Biosynthetic Process Cell Junction Assembly Regulation Of Cell Proliferation SMAD Protein Complex Assembly Negative Regulation Of Cell Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cellular Component Movement Signal Transduction Cellular Response To Organic Cyclic Compound Organ Development Anatomical Structure Morphogenesis Cellular Component Assembly Cell-cell Junction Organization Positive Regulation Of Transcription, DNA-templated Renal System Development Negative Regulation Of Signaling Regulation Of Cell Motility Gastrulation Cell-cell Signaling Regulation Of Cell Differentiation Negative Regulation Of Signal Transduction Regulation Of Locomotion Response To Wounding Urogenital System Development Regulation Of Cell Migration System Development Regulation Of Epithelial Cell Proliferation Adherens Junction Organization Positive Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Multicellular Organismal Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Kidney Development Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Neurotrophin TRK Receptor Signaling Pathway
Tagcloud ?		ch comprises counseling dehal1 deiodinase duox2 duoxa2 dysgenesis dyshormonogenesis foxe1 inheritance iodine iodotyrosine iyd malformations monogenetic nkx2 organification organogenesis outlined pax8 preceded radiological slc26a4 syndromic td thyroglobulin thyroidal utero	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Difference) ?		ch comprises counseling dehal1 deiodinase duox2 duoxa2 dysgenesis dyshormonogenesis foxe1 inheritance iodine iodotyrosine iyd malformations monogenetic nkx2 organification organogenesis outlined pax8 preceded radiological slc26a4 syndromic td thyroglobulin thyroidal utero	adoptive cd4 cholangiocarcinoma contained exists exomic experienced harnessed helper humans infiltrating interacting lymphocytes mediate metastatic mount mutated mutation polyfunctional prolonged pure recognizing regression retreated sequencing stabilization til transfer
Tagcloud (Intersection) ?