APOBEC3F

Name	apolipoprotein B mRNA editing enzyme catalytic subunit 3F
Structure
Novel Interactors	1 novel interactors: TYK2
Interactors	5 interactors: ACD APOBEC3G ARIH2 RNF7 TINF2
GO Annotations	Cellular Component	P-body Nucleus Cytoplasm Apolipoprotein B MRNA Editing Enzyme Complex Ribonucleoprotein Complex
	Molecular Function	RNA Binding Catalytic Activity Cytidine Deaminase Activity Protein Binding Zinc Ion Binding Hydrolase Activity Identical Protein Binding Metal Ion Binding
	Biological Process	Positive Regulation Of Defense Response To Virus By Host Immune System Process Transposable Element Silencing Negative Regulation Of Macromolecule Biosynthetic Process Base Conversion Or Substitution Editing Cytidine To Uridine Editing Positive Regulation Of Gene Expression Via Chromosomal CpG Island Demethylation Clearance Of Foreign Intracellular DNA Negative Regulation Of Viral Genome Replication Innate Immune Response Negative Regulation Of Single Stranded Viral RNA Replication Via Double Stranded DNA Intermediate Negative Regulation Of Viral Process Defense Response To Virus DNA Cytosine Deamination Antiviral Innate Immune Response
GWAS	No GWAS studies recorded
Entrez ID	200316
HPRD ID	16415
Ensembl ID	ENSG00000128394
Uniprot IDs	Q8IUX4
PDB IDs	3WUS 4IOU 4J4J 5HX4 5HX5 5W2M 5ZVA 5ZVB 6NIL
GO Terms Enriched among Interactors ?	Telomere Assembly Shelterin Complex Response To Virus Nuclear Telomere Cap Complex Protein Localization To Chromosome, Telomeric Region Telomere Capping Growth Hormone Receptor Signaling Pathway Via JAK-STAT Cul5-RING Ubiquitin Ligase Complex Negative Regulation Of Telomere Maintenance Via Telomerase Growth Hormone Receptor Signaling Pathway Telomeric DNA Binding Negative Regulation Of DNA Biosynthetic Process Negative Regulation Of Telomere Maintenance Via Telomere Lengthening Negative Regulation Of Telomere Maintenance Defense Response To Virus Regulation Of Telomere Maintenance Via Telomerase Regulation Of Telomere Maintenance Via Telomere Lengthening Response To Other Organism Positive Regulation Of Telomere Maintenance Immune Response Negative Regulation Of Chromosome Organization DCTP Deaminase Activity Regulation Of DNA Biosynthetic Process Response To External Biotic Stimulus Macromolecule Metabolic Process Telomere Maintenance Positive Regulation Of Chromosome Organization Protein Localization To Chromosome Regulation Of Telomere Maintenance Perinucleolar Chromocenter Telomere Organization Negative Regulation Of DNA Metabolic Process Innate Immune Response Interleukin-12 Receptor Complex Negative Regulation Of Focal Adhesion Disassembly Negative Regulation Of Cellular Component Organization Interleukin-23 Receptor Complex NEDD8 Ligase Activity DNA Metabolic Process Defense Response To Symbiont Chromosome, Telomeric Region Defense Response To Other Organism Immune System Process NEDD8 Transferase Activity Interleukin-23-mediated Signaling Pathway Positive Regulation Of NK T Cell Proliferation Phosphocreatine Biosynthetic Process Apolipoprotein B MRNA Editing Enzyme Complex Regulation Of Establishment Of Protein Localization To Telomere Regulation Of Establishment Of Protein Localization To Chromosome