FKBP1B

Gene Name		FK506 binding protein 1B, 12.6 kDa
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Gene Ontology Annotations	Cellular Component	Cytoplasm Cytosol Membrane Z Disc Sarcoplasmic Reticulum Membrane Calcium Channel Complex
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Receptor Binding Ryanodine-sensitive Calcium-release Channel Activity Protein Binding FK506 Binding Calcium Channel Inhibitor Activity Cyclic Nucleotide Binding Ion Channel Binding
	Biological Process	Protein Peptidyl-prolyl Isomerization 'de Novo' Protein Folding Smooth Muscle Contraction Response To Glucose Negative Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Neuronal Action Potential Propagation Protein Maturation By Protein Folding Insulin Secretion Negative Regulation Of Protein Phosphatase Type 2B Activity Response To Vitamin E Ion Transmembrane Transport Calcium-mediated Signaling Using Intracellular Calcium Source Protein Refolding T Cell Proliferation Response To Hydrogen Peroxide Positive Regulation Of Axon Regeneration Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Sequestering Of Calcium Ion Cytosolic Calcium Ion Homeostasis Response To Redox State Transmembrane Transport Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Chaperone-mediated Protein Folding Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Calcium Ion Transmembrane Transport Cell Communication By Electrical Coupling Involved In Cardiac Conduction
Pathways		Ion channel transport Stimuli-sensing channels
Drugs
Diseases
GWAS		Quantitative traits ( 19197348)
Protein-protein Interactions		9 interactors: ADAMTSL4 BMPR1A CAMK2D GMCL1 KRT31 KRT40 REL RYR2 TRIM69
Entrez ID		2281
HPRD ID		02795
Ensembl ID		ENSG00000119782
Uniprot IDs		P68106
PDB IDs		1C9H 4C02
Enriched GO Terms of Interacting Partners?		Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cardiac Muscle Hypertrophy Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Muscle Hypertrophy Regulation Of The Force Of Heart Contraction Regulation Of Cardiac Muscle Cell Contraction Cardiac Conduction Cardiac Muscle Contraction Regulation Of Calcium Ion Transmembrane Transport Regulation Of Calcium Ion Transmembrane Transporter Activity Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Heart Contraction Regulation Of Heart Rate Regulation Of Cardiac Muscle Contraction BMP Signaling Pathway Regulation Of Cation Channel Activity Regulation Of Calcium Ion Transport Into Cytosol Regulation Of Intracellular Transport Neural Plate Mediolateral Regionalization Left Ventricular Cardiac Muscle Tissue Morphogenesis Paraxial Mesoderm Structural Organization Positive Regulation Of Calcium-transporting ATPase Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity By Adrenergic Receptor Signaling Pathway Involved In Positive Regulation Of Cardiac Muscle Contraction Striated Muscle Contraction Regulation Of Striated Muscle Contraction Calcium-mediated Signaling Heart Development Positive Regulation Of Sequestering Of Calcium Ion Type B Pancreatic Cell Apoptotic Process Response To Calcium Ion Second-messenger-mediated Signaling Regulation Of Cardiac Muscle Cell Action Potential Involved In Regulation Of Contraction Cardiac Muscle Cell Contraction Regulation Of Calcium-transporting ATPase Activity Adrenergic Receptor Signaling Pathway Involved In Heart Process Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity Regulation Of Muscle Contraction Regulation Of Ion Homeostasis Regulation Of Generation Of L-type Calcium Current Mesendoderm Development Regulation Of Lateral Mesodermal Cell Fate Specification Positive Regulation Of The Force Of Heart Contraction G-protein Coupled Receptor Signaling Pathway Involved In Heart Process Regulation Of Heart Contraction Tissue Development Positive Regulation Of Rac Protein Signal Transduction
Tagcloud ?		aav abcc8 adeno administrations cxcl12 cxcl13 damaged foxa2 g6pc2 gad1 glp glucosamine glut2 isl1 islets neurod1 nitrosourea nkx6 nptx2 pdx1 preserve prss53 sdf slc2a2 slc30a8 stz tmem229b ttc28 ucn3