FKBP1B and RYR3

Number of citations of the paper that reports this interaction (PubMedID 11598113)
0

Data Source:
BioGRID (pull down)

		FKBP1B	RYR3
Description		FKBP prolyl isomerase 1B	ryanodine receptor 3
Image
GO Annotations	Cellular Component	Cytoplasm Membrane Sarcoplasmic Reticulum Z Disc Sarcoplasmic Reticulum Membrane Calcium Channel Complex	Smooth Endoplasmic Reticulum Membrane Sarcoplasmic Reticulum Z Disc Sarcoplasmic Reticulum Membrane Calcium Channel Complex Sarcolemma
	Molecular Function	Peptidyl-prolyl Cis-trans Isomerase Activity Signaling Receptor Binding Calcium Channel Regulator Activity Protein Binding FK506 Binding Isomerase Activity Calcium Channel Inhibitor Activity Transmembrane Transporter Binding	Monoatomic Ion Channel Activity Ryanodine-sensitive Calcium-release Channel Activity Calcium Channel Activity Calcium Ion Binding Calmodulin Binding Intracellularly Gated Calcium Channel Activity Calcium-induced Calcium Release Activity
	Biological Process	Regulation Of Heart Rate Protein Folding 'de Novo' Protein Folding Smooth Muscle Contraction Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Glucose Negative Regulation Of Heart Rate Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Neuronal Action Potential Propagation Calcium-mediated Signaling Insulin Secretion Insulin Secretion Involved In Cellular Response To Glucose Stimulus Protein Refolding T Cell Proliferation Negative Regulation Of Calcium-mediated Signaling Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Sequestering Of Calcium Ion Protein Maturation Response To Redox State Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Negative Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus	Monoatomic Ion Transport Calcium Ion Transport Intracellular Calcium Ion Homeostasis Striated Muscle Contraction Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Calcium-mediated Signaling Monoatomic Ion Transmembrane Transport Release Of Sequestered Calcium Ion Into Cytosol Protein Homotetramerization Transmembrane Transport Calcium Ion Transmembrane Transport Cellular Response To Calcium Ion Cellular Response To Magnesium Ion Cellular Response To Caffeine Cellular Response To ATP
Pathways		Stimuli-sensing channels Ion homeostasis	Stimuli-sensing channels Ion homeostasis
Drugs
Diseases
GWAS		Chronotype ( 27494321) Quantitative traits ( 19197348)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid atherosclerosis in HIV infection ( 20009918) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Hepcidin/ferritin ratio ( 27846281) Hippocampal volume ( 31530798) Malaria ( 31844061) Parkinson's disease progression (cognitive) ( 33958783) Periodontitis (Mean PAL) ( 24024966) Schizophrenia ( 30285260) Urinary albumin excretion ( 32277301)
Interacting Genes		12 interacting genes: ADAMTSL4 BMPR1A CAMK2D GMCL1 KRT31 KRT40 KRTAP1-1 REL RYR2 RYR3 TGFBR1 TRIM69	7 interacting genes: BCL2L1 FKBP1A FKBP1B HNF1A RYR2 SRI TIAM1
Entrez ID		2281	6263
HPRD ID		02795	01620
Ensembl ID		ENSG00000119782	ENSG00000198838
Uniprot IDs		F8W6G9 P68106	A0A0U1RRH1 Q15413
PDB IDs		1C9H 4C02 4IQ2 4IQC 5HKG 5L1D 5T15 5T9M 5T9N 5T9R 5T9S 5T9V 5TA3 5TAL 5TAM 5TAN 5TAP 5TAQ 5TAS 5TAT 5TAU 5TAV 5TAW 5TAX 5TAY 5TAZ 5TB0 5TB1 5TB2 5TB3 5TB4 6JGZ 6JH6 6JHN 6JI0 6JI8 6JII 6JIU 6JIY 6JRR 6JRS 6M2W 6PV6 6W1N 6WOT 6WOU 6WOV 6X32 6X33 6X34 6X35 6X36 7CF9 7JMF 7JMG 7JMH 7JMI 7JMJ 7M6A 7M6L 7T64 7T65 7U9Q 7U9R 7U9T 7U9X 7U9Z 7UA1 7UA3 7UA4 7UA5 7UA9 7VML 7VMM 7VMN 7VMO 7VMP 7VMQ 7VMR 7VMS 8DTY 8DTZ 8DUJ 8DVE 8DVV 8SEN 8SEO 8SEP 8SEQ 8SER 8SES 8SET 8UQ2 8UQ3 8UQ4 8UXC 8UXE 8UXF 8UXG 8UXH 8UXI 8UXL 8UXM 8XJI 8XKH 8XLF 8XLH 8Y40 9C1E 9C1F 9CGP 9CGQ	4ERV 6UHA 6UHB 6UHE 6UHH
Enriched GO Terms of Interacting Partners?		Ventricular Cardiac Muscle Tissue Morphogenesis Tissue Morphogenesis Transforming Growth Factor Beta Receptor Activity, Type I Sarcoplasmic Reticulum Membrane Calcium-induced Calcium Release Activity Ryanodine-sensitive Calcium-release Channel Activity Cardiac Muscle Tissue Morphogenesis Muscle Tissue Morphogenesis Ventricular Compact Myocardium Morphogenesis Sarcoplasmic Reticulum Intracellularly Gated Calcium Channel Activity Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cellular Response To Caffeine Release Of Sequestered Calcium Ion Into Cytosol By Endoplasmic Reticulum Transmembrane Receptor Protein Serine/threonine Kinase Activity Cellular Response To Purine-containing Compound Keratin Filament Ventricular Trabecula Myocardium Morphogenesis Sarcoplasmic Reticulum Calcium Ion Transport Response To Caffeine Sarcolemma Smooth Endoplasmic Reticulum Heart Trabecula Morphogenesis Regulation Of Sequestering Of Calcium Ion Response To Calcium Ion Intracellular Monoatomic Cation Homeostasis Inorganic Ion Homeostasis Intracellular Monoatomic Ion Homeostasis Regulation Of The Force Of Heart Contraction Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Calcium Channel Complex Intermediate Filament Regulation Of Cardiac Muscle Cell Action Potential Calcium-mediated Signaling Monoatomic Cation Homeostasis Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Monoatomic Ion Homeostasis Intracellular Calcium Ion Homeostasis Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Calmodulin Binding Cellular Response To Alkaloid Ventricular Septum Morphogenesis Regulation Of Cardiac Muscle Cell Proliferation Intracellular Chemical Homeostasis Positive Regulation Of SMAD Protein Signal Transduction Calcium Ion Homeostasis SMAD Binding Regulation Of Cardiac Muscle Cell Apoptotic Process Regulation Of Neural Crest Cell Differentiation Neural Plate Mediolateral Regionalization	Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cardiac Muscle Contraction Regulation Of Striated Muscle Contraction Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Regulation Of Sequestering Of Calcium Ion Z Disc Transmembrane Transporter Binding Regulation Of Calcium Ion Transmembrane Transport Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Muscle Contraction Regulation Of Heart Contraction Calcium Channel Regulator Activity Regulation Of Calcium Ion Transport Regulation Of Muscle System Process Regulation Of Blood Circulation Regulation Of Monoatomic Cation Transmembrane Transport Regulation Of Monoatomic Ion Transmembrane Transport Positive Regulation Of Sequestering Of Calcium Ion Regulation Of Metal Ion Transport FK506 Binding 'de Novo' Protein Folding Regulation Of Heart Rate Negative Regulation Of Heart Rate Regulation Of Monoatomic Ion Transport Response To Redox State Negative Regulation Of Heart Contraction Calcium-mediated Signaling Regulation Of System Process Negative Regulation Of Blood Circulation Calcium Channel Complex Protein Refolding Regulation Of Cardiac Muscle Cell Contraction Peptidyl-prolyl Cis-trans Isomerase Activity Cellular Response To Alkaloid Calcium Ion Transport Regulation Of Transport Ventricular Cardiac Muscle Tissue Morphogenesis Epithelial Cell Apoptotic Process Insulin Secretion Intracellular Signaling Cassette Intracellular Signal Transduction Regulation Of Protein Localization Cardiac Muscle Tissue Morphogenesis Release Of Sequestered Calcium Ion Into Cytosol Negative Regulation Of Sequestering Of Calcium Ion Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Peptide Hormone Secretion
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