MFAP1 and DHX8

Number of citations of the paper that reports this interaction (PMID 22365833)
24

Data Source:
BioGRID (two hybrid, two hybrid)

		MFAP1	DHX8
Gene Name		microfibrillar-associated protein 1	DEAH (Asp-Glu-Ala-His) box polypeptide 8
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Microfibril Extracellular Region	Nucleus Nucleoplasm Spliceosomal Complex Cytoplasm Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	ATP-dependent RNA Helicase Activity Protein Binding ATP Binding Identical Protein Binding Poly(A) RNA Binding
	Biological Process	Biological_process Extracellular Matrix Organization	MRNA Splicing, Via Spliceosome RNA Processing RNA Splicing
Pathways		Molecules associated with elastic fibres Elastic fibre formation
Drugs
Diseases
GWAS
Protein-Protein Interactions		47 interactors: AES AMOTL2 BEND7 CARD9 CCDC57 CDCA7L CEP55 CEP57L1 CEP70 COIL CSNK2A1 DHX38 DHX8 FAM9B FRA10AC1 FXR2 GKAP1 GOLGA2 HMBOX1 HSPB1 IK KATNBL1 KIFC3 KRT40 LDOC1 MAD1L1 MID2 MIPOL1 MTUS2 NDC80 PHC2 SART1 SMU1 SNIP1 SNW1 SSX2IP STX11 TADA2A TRIM42 TRIM54 U2AF1 VPS52 YWHAG ZBTB14 ZBTB8A ZFP64 ZNF398	11 interactors: MFAP1 NKAP PRPF38A PRPF40A RBM7 RBMX2 SAP30BP SRPK1 SRPK2 THOC1 ZCCHC10
Entrez ID		4236	1659
HPRD ID		02569	02672
Ensembl ID		ENSG00000140259	ENSG00000067596
Uniprot IDs		P55081	F5H658 Q14562
PDB IDs			2EQS 3I4U
Enriched GO Terms of Interacting Partners?		Mitotic Cell Cycle Gene Expression MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Metabolic Process Mitotic Cell Cycle Process Transcription, DNA-templated RNA Biosynthetic Process Cell Cycle Process Cell Cycle RNA Splicing RNA Processing Regulation Of Chromosome Organization Regulation Of Tumor Necrosis Factor Biosynthetic Process MRNA Processing Negative Regulation Of Cellular Metabolic Process Positive Regulation Of MRNA Splicing, Via Spliceosome MRNA Metabolic Process Mitotic Spindle Checkpoint Negative Regulation Of Chromosome Segregation Nucleobase-containing Compound Metabolic Process Positive Regulation Of RNA Splicing Termination Of RNA Polymerase II Transcription Maturation Of 5S RRNA Regulation Of Metaphase Plate Congression Regulation Of Mitotic Sister Chromatid Separation Negative Regulation Of Mitotic Nuclear Division Spindle Checkpoint Regulation Of Organelle Organization Regulation Of Mitotic Metaphase/anaphase Transition Microtubule Anchoring Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Gene Expression Positive Regulation Of Cytotoxic T Cell Differentiation Positive Regulation Of Vitamin D Receptor Signaling Pathway Embryonic Ectodermal Digestive Tract Development Negative Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Protein Binding Positive Regulation Of Tumor Necrosis Factor Production Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Proteasomal Protein Catabolic Process Cellular Macromolecule Biosynthetic Process Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome Zonula Adherens Maintenance Microtubule-based Process MRNA Export From Nucleus Regulation Of I-kappaB Kinase/NF-kappaB Signaling	RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing RNA Metabolic Process Positive Regulation Of Viral Genome Replication Gene Expression Negative Regulation Of Viral Genome Replication Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Viral Genome Replication Positive Regulation Of Viral Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Negative Regulation Of Viral Process Negative Regulation Of Isotype Switching To IgA Isotypes Nuclear Speck Organization Cellular Nitrogen Compound Metabolic Process Regulation Of MRNA Processing Regulation Of RNA Splicing Nitrogen Compound Metabolic Process Nucleus Organization Negative Regulation Of DNA Damage Checkpoint Regulation Of Viral Process Viral MRNA Export From Host Cell Nucleus Sperm Chromatin Condensation Regulation Of Cell Cycle Regulation Of DNA Damage Checkpoint Hematopoietic Stem Cell Proliferation Replication Fork Processing Granulocyte Differentiation Negative Regulation Of DNA Recombination Regulation Of Lymphocyte Activation
Tagcloud ?			avenues bioinformatics bl canonical conferring disrupted dnaja1 galactosidase gtf2e1 gtf2e2 hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Difference) ?			avenues bioinformatics bl canonical conferring disrupted dnaja1 galactosidase gtf2e1 gtf2e2 hap1 insertional kalrn lytic mechanistic mutagenesis participate queried replication screens share tat throughput tzm uba3 ube2e3 utilizing viable vmp1
Tagcloud (Intersection) ?