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SEMG2 and PRKAR2A
Number of citations of the paper that reports this interaction (PMID
12399526
)
0
Data Source:
HPRD
(in vitro, in vivo)
SEMG2
PRKAR2A
Gene Name
semenogelin II
protein kinase, cAMP-dependent, regulatory, type II, alpha
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Nucleus
Secretory Granule
Extracellular Vesicular Exosome
Cytoplasm
Centrosome
Cytosol
Plasma Membrane
Focal Adhesion
CAMP-dependent Protein Kinase Complex
Membrane
AMP-activated Protein Kinase Complex
Extracellular Vesicular Exosome
Ciliary Base
Molecular Function
Structural Molecule Activity
CAMP-dependent Protein Kinase Inhibitor Activity
Protein Binding
CAMP-dependent Protein Kinase Regulator Activity
CAMP Binding
Ubiquitin Protein Ligase Binding
Protein Kinase A Catalytic Subunit Binding
Biological Process
Sexual Reproduction
Renal Water Homeostasis
Energy Reserve Metabolic Process
Water Transport
Signal Transduction
Epidermal Growth Factor Receptor Signaling Pathway
Activation Of Phospholipase C Activity
Blood Coagulation
Fibroblast Growth Factor Receptor Signaling Pathway
Activation Of Protein Kinase A Activity
Intracellular Signal Transduction
Small Molecule Metabolic Process
Innate Immune Response
Neurotrophin TRK Receptor Signaling Pathway
Regulation Of Insulin Secretion
Transmembrane Transport
Cellular Response To Glucagon Stimulus
Negative Regulation Of CAMP-dependent Protein Kinase Activity
Pathways
Signaling by GPCR
Ca-dependent events
CaM pathway
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion
Hedgehog 'off' state
Integration of energy metabolism
Phospholipase C-mediated cascade
Signaling by FGFR in disease
Signaling by EGFRvIII in Cancer
PLCG1 events in ERBB2 signaling
DAG and IP3 signaling
CaM pathway
DAP12 signaling
Downstream signaling of activated FGFR
DARPP-32 events
Glucagon signaling in metabolic regulation
Innate Immune System
Signaling by PDGF
PKA activation in glucagon signalling
Calmodulin induced events
Signalling by NGF
DAP12 interactions
PKA-mediated phosphorylation of CREB
PLC beta mediated events
Vasopressin regulates renal water homeostasis via Aquaporins
Opioid Signalling
Regulation of insulin secretion
Signaling by Ligand-Responsive EGFR Variants in Cancer
NGF signalling via TRKA from the plasma membrane
G-protein mediated events
PKA activation
Factors involved in megakaryocyte development and platelet production
Signaling by Overexpressed Wild-Type EGFR in Cancer
Aquaporin-mediated transport
Signaling by FGFR
EGFR interacts with phospholipase C-gamma
Signaling by ERBB2
PKA-mediated phosphorylation of CREB
Signaling by EGFR
Downstream signal transduction
Calmodulin induced events
Signaling by Hedgehog
PLC-gamma1 signalling
Signaling by EGFR in Cancer
PKA activation
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
KLK2
KLK3
PRKAR2A
PRKCA
SEMG1
SERPINA5
TGM1
33 interactors:
AKAP1
AKAP10
AKAP11
AKAP12
AKAP13
AKAP14
AKAP2
AKAP3
AKAP4
AKAP5
AKAP6
AKAP7
AKAP8
AKAP9
ARFGEF2
CBFA2T3
CFTR
EZR
MAP2
MYCBPAP
NBEA
PJA2
PPP1CB
PRKX
RAB32
RET
RUNX1T1
RYR2
SCTR
SEMG2
SMAD3
SMAD4
WASF1
Entrez ID
6407
5576
HPRD ID
01642
01484
Ensembl ID
ENSG00000124157
ENSG00000114302
Uniprot IDs
Q02383
P13861
Q9BUB1
PDB IDs
2IZX
2KYG
Enriched GO Terms of Interacting Partners
?
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Response To Wounding
Activation Of Phospholipase C Activity
Positive Regulation Of Phospholipase C Activity
Extracellular Matrix Organization
Extracellular Structure Organization
Positive Regulation Of Phospholipase Activity
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Positive Regulation Of Dense Core Granule Biogenesis
Extracellular Matrix Disassembly
Positive Regulation Of Inflammatory Response
Regulation Of Blood Coagulation
Factor XII Activation
Cell Envelope Organization
Histone H3-T6 Phosphorylation
Regulation Of Wound Healing
Negative Regulation Of Protein Serine/threonine Kinase Activity
Energy Reserve Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Catalytic Activity
Positive Regulation Of Fibrinolysis
Negative Regulation Of Cellular Protein Metabolic Process
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of Insulin Secretion
Negative Regulation Of Protein Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Protein Kinase Activity
Regulation Of Peptide Hormone Secretion
Regulation Of Angiogenesis
Neurotrophin Signaling Pathway
Peptidyl-serine Autophosphorylation
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Negative Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Negative Regulation Of CAMP-dependent Protein Kinase Activity
Plasminogen Activation
Regulation Of Hormone Secretion
Desmosome Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Regulation Of Inflammatory Response
Plasma Kallikrein-kinin Cascade
Energy Derivation By Oxidation Of Organic Compounds
Negative Regulation Of Glucose Import
Regulation Of Protein Kinase A Signaling
Positive Regulation Of Ion Transmembrane Transporter Activity
Positive Regulation Of Transporter Activity
Positive Regulation Of Ion Transmembrane Transport
Positive Regulation Of Potassium Ion Transmembrane Transporter Activity
Signaling
Cellular Response To CAMP
Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway
Cell Communication
Signal Transduction
Regulation Of Ion Transmembrane Transporter Activity
Cellular Response To Stimulus
Regulation Of Transmembrane Transporter Activity
Positive Regulation Of Potassium Ion Transmembrane Transport
Response To Stimulus
Protein Localization
Response To Purine-containing Compound
Regulation Of Membrane Repolarization
Regulation Of Signal Transduction
Positive Regulation Of Ion Transport
Regulation Of Potassium Ion Transmembrane Transporter Activity
Positive Regulation Of Potassium Ion Transport
Positive Regulation Of Delayed Rectifier Potassium Channel Activity
Positive Regulation Of Cation Channel Activity
Cellular Response To Organic Cyclic Compound
Regulation Of Signaling
Enzyme Linked Receptor Protein Signaling Pathway
Cellular Response To Organic Substance
Intracellular Signal Transduction
Positive Regulation Of Protein Kinase A Signaling
Regulation Of Potassium Ion Transmembrane Transport
Response To CAMP
Regulation Of Membrane Potential
Positive Regulation Of Transport
Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity
SMAD Protein Complex Assembly
Response To Organophosphorus
Regulation Of Delayed Rectifier Potassium Channel Activity
Sexual Reproduction
Regulation Of Transforming Growth Factor Beta2 Production
Regulation Of Potassium Ion Transport
Epithelial Tube Morphogenesis
Regulation Of Cation Channel Activity
Regulation Of Ion Transmembrane Transport
Action Potential
Tube Morphogenesis
Regulation Of CAMP Biosynthetic Process
Regulation Of Cellular Process
Response To Organic Substance
Positive Regulation Of Protein Import Into Nucleus
Tagcloud
?
agouti
albinism
asip
atf1
delta25
dopachrome
edn1
edn3
ednrb
exoc2
exocyst
kitlg
ludwigshafen
mc1r
microphthalmia
oca2
oculocutaneous
pigmentation
prkacb
prkacg
proopiomelanocortin
slc24a4
slc45a2
tautomerase
tpcn2
tubb3
tyrp1
Tagcloud (Difference)
?
agouti
albinism
asip
atf1
delta25
dopachrome
edn1
edn3
ednrb
exoc2
exocyst
kitlg
ludwigshafen
mc1r
microphthalmia
oca2
oculocutaneous
pigmentation
prkacb
prkacg
proopiomelanocortin
slc24a4
slc45a2
tautomerase
tpcn2
tubb3
tyrp1
Tagcloud (Intersection)
?