SEMG2

Description		semenogelin 2
Image		No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Extracellular Region Extracellular Space Nucleus Extracellular Exosome
	Molecular Function	Protease Binding Protein Binding Zinc Ion Binding
	Biological Process	Antibacterial Humoral Response Sperm Capacitation Coagulation Positive Regulation Of Serine-type Endopeptidase Activity Negative Regulation Of Flagellated Sperm Motility
Pathways
Drugs		Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Asthma ( 29273806) Bipolar disorder ( 31043756) Malaria ( 31844061)
Interacting Genes		8 interacting genes: KLK2 KLK3 PRKAR2A PRKCA PTPRF SEMG1 SERPINA5 TGM1
Entrez ID		6407
HPRD ID		01642
Ensembl ID		ENSG00000124157
Uniprot IDs		Q02383
PDB IDs
Enriched GO Terms of Interacting Partners?		Extracellular Exosome Protein-containing Complex Zymogen Activation Regulation Of Systemic Arterial Blood Pressure Protein C Inhibitor-coagulation Factor V Complex Protein C Inhibitor-TMPRSS7 Complex Protein C Inhibitor-PLAU Complex Protein C Inhibitor-TMPRSS11E Complex Protein C Inhibitor-coagulation Factor Xa Complex Protein C Inhibitor-KLK3 Complex Protein C Inhibitor-plasma Kallikrein Complex Protein C Inhibitor-thrombin Complex Protein C Inhibitor-coagulation Factor XI Complex Protein C Inhibitor-PLAT Complex Chondroitin Sulfate Proteoglycan Binding Serine-type Peptidase Activity Secretory Granule Platelet Dense Tubular Network Seminal Clot Liquefaction Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex Negative Regulation Of Flagellated Sperm Motility Positive Regulation Of Serine-type Endopeptidase Activity Cell Envelope Organization Positive Regulation Of Antibacterial Peptide Production Acrosin Binding Protein Kinase C Signaling Negative Regulation Of Receptor Binding Insemination Serine-type Endopeptidase Activity Heparin Binding Regulation Of Angiotensin-activated Signaling Pathway Regulation Of Blood Pressure Regulation Of Antibacterial Peptide Production Positive Regulation Of Antimicrobial Peptide Production Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Extracellular Space Protein Processing Positive Regulation Of Antimicrobial Humoral Response CAMP-dependent Protein Kinase Regulator Activity Desmosome Assembly Cell Surface Receptor Protein Tyrosine Phosphatase Signaling Pathway Protein-glutamine Gamma-glutamyltransferase Activity Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Endopeptidase Activity Regulation Of Antimicrobial Humoral Response Protein Metabolic Process
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