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SEMG2 and SERPINA5
Number of citations of the paper that reports this interaction (PMID
8665956
)
6
Data Source:
HPRD
(in vitro)
SEMG2
SERPINA5
Gene Name
semenogelin II
serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Extracellular Space
Nucleus
Secretory Granule
Extracellular Vesicular Exosome
Acrosomal Membrane
Extracellular Region
Extracellular Space
External Side Of Plasma Membrane
Membrane
Platelet Alpha Granule
Platelet Dense Tubular Network
Protein C Inhibitor-TMPRSS7 Complex
Protein C Inhibitor-TMPRSS11E Complex
Protein C Inhibitor-PLAT Complex
Protein C Inhibitor-PLAU Complex
Protein C Inhibitor-thrombin Complex
Protein C Inhibitor-KLK3 Complex
Protein C Inhibitor-plasma Kallikrein Complex
Protein Complex
Extracellular Vesicular Exosome
Protein C Inhibitor-coagulation Factor V Complex
Protein C Inhibitor-coagulation Factor Xa Complex
Protein C Inhibitor-coagulation Factor XI Complex
Molecular Function
Structural Molecule Activity
Retinoic Acid Binding
Protease Binding
Serine-type Endopeptidase Inhibitor Activity
Glycosaminoglycan Binding
Heparin Binding
Phosphatidylcholine Binding
Acrosin Binding
Biological Process
Sexual Reproduction
Lipid Transport
Spermatogenesis
Fusion Of Sperm To Egg Plasma Membrane
Blood Coagulation
Negative Regulation Of Endopeptidase Activity
Pathways
Common Pathway
Intrinsic Pathway
Formation of Fibrin Clot (Clotting Cascade)
Drugs
Diseases
GWAS
Protein-Protein Interactions
7 interactors:
KLK2
KLK3
PRKAR2A
PRKCA
SEMG1
SERPINA5
TGM1
20 interactors:
ACR
COPS6
F10
F11
F2
FGA
FGB
FGG
HRSP12
KLK1
KLK2
KLK3
KLKB1
PIAS4
PLAT
PLAU
PROC
RCHY1
SEMG2
THBD
Entrez ID
6407
5104
HPRD ID
01642
03503
Ensembl ID
ENSG00000124157
ENSG00000188488
Uniprot IDs
Q02383
B3KTV6
B4DDH1
B4DPC7
P05154
PDB IDs
1LQ8
1PAI
2HI9
2OL2
2PAI
3DY0
Enriched GO Terms of Interacting Partners
?
Blood Coagulation
Hemostasis
Regulation Of Body Fluid Levels
Wound Healing
Response To Wounding
Activation Of Phospholipase C Activity
Positive Regulation Of Phospholipase C Activity
Extracellular Matrix Organization
Extracellular Structure Organization
Positive Regulation Of Phospholipase Activity
Regulation Of Phospholipase Activity
Positive Regulation Of Lipase Activity
Positive Regulation Of Dense Core Granule Biogenesis
Extracellular Matrix Disassembly
Positive Regulation Of Inflammatory Response
Regulation Of Blood Coagulation
Factor XII Activation
Cell Envelope Organization
Histone H3-T6 Phosphorylation
Regulation Of Wound Healing
Negative Regulation Of Protein Serine/threonine Kinase Activity
Energy Reserve Metabolic Process
Epidermal Growth Factor Receptor Signaling Pathway
ERBB Signaling Pathway
Fibroblast Growth Factor Receptor Signaling Pathway
Negative Regulation Of Catalytic Activity
Positive Regulation Of Fibrinolysis
Negative Regulation Of Cellular Protein Metabolic Process
Cellular Response To Fibroblast Growth Factor Stimulus
Response To Fibroblast Growth Factor
Regulation Of Insulin Secretion
Negative Regulation Of Protein Metabolic Process
Neurotrophin TRK Receptor Signaling Pathway
Negative Regulation Of Protein Kinase Activity
Regulation Of Peptide Hormone Secretion
Regulation Of Angiogenesis
Neurotrophin Signaling Pathway
Peptidyl-serine Autophosphorylation
Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway
Negative Regulation Of Kinase Activity
Regulation Of Protein Metabolic Process
Negative Regulation Of CAMP-dependent Protein Kinase Activity
Plasminogen Activation
Regulation Of Hormone Secretion
Desmosome Assembly
Negative Regulation Of Glial Cell Apoptotic Process
Regulation Of Inflammatory Response
Plasma Kallikrein-kinin Cascade
Energy Derivation By Oxidation Of Organic Compounds
Negative Regulation Of Glucose Import
Negative Regulation Of Blood Coagulation
Negative Regulation Of Coagulation
Negative Regulation Of Wound Healing
Regulation Of Blood Coagulation
Blood Coagulation
Hemostasis
Regulation Of Wound Healing
Regulation Of Body Fluid Levels
Wound Healing
Response To Wounding
Regulation Of Fibrinolysis
Blood Coagulation, Intrinsic Pathway
Plasminogen Activation
Fibrinolysis
Proteolysis
Protein Activation Cascade
Positive Regulation Of Fibrinolysis
Positive Regulation Of Heterotypic Cell-cell Adhesion
Peptidyl-glutamic Acid Carboxylation
Extracellular Matrix Organization
Extracellular Structure Organization
Negative Regulation Of Endothelial Cell Apoptotic Process
Protein Metabolic Process
Positive Regulation Of Substrate Adhesion-dependent Cell Spreading
Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Zymogen Activation
Factor XII Activation
Positive Regulation Of Vasoconstriction
Regulation Of Substrate Adhesion-dependent Cell Spreading
Response To Stress
Regulation Of Endothelial Cell Apoptotic Process
Platelet Aggregation
Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors
Regulation Of Vasoconstriction
Platelet Activation
Positive Regulation Of Exocytosis
Regulation Of Cell-substrate Adhesion
Platelet Degranulation
Negative Regulation Of Fibrinolysis
Acute Inflammatory Response
Plasma Kallikrein-kinin Cascade
Positive Regulation Of Intracellular Signal Transduction
Positive Regulation Of Peptide Hormone Secretion
Protein Processing
Positive Regulation Of Peptide Secretion
Extracellular Matrix Disassembly
Protein Polymerization
Positive Regulation Of Hormone Secretion
Negative Regulation Of Platelet Activation
Response To Calcium Ion
Tagcloud
?
across
agr2
assigned
differently
effector
endocrine
ergs
estradiol
exploitable
greb1
interpretation
menstrual
mirroring
pdzk1
pgr
premenopausal
progesterone
rankl
responsiveness
rhythm
runx1
tff1
tumours
varies
w1
w2
w3
windows
Tagcloud (Difference)
?
across
agr2
assigned
differently
effector
endocrine
ergs
estradiol
exploitable
greb1
interpretation
menstrual
mirroring
pdzk1
pgr
premenopausal
progesterone
rankl
responsiveness
rhythm
runx1
tff1
tumours
varies
w1
w2
w3
windows
Tagcloud (Intersection)
?