BLOC1S2 and C8orf33

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		BLOC1S2	C8orf33
Gene Name		biogenesis of lysosomal organelles complex-1, subunit 2	chromosome 8 open reading frame 33
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Gamma-tubulin Complex Nucleus Mitochondrion Centrosome BLOC-1 Complex Recycling Endosome
	Molecular Function	Protein Binding Protein C-terminus Binding Gamma-tubulin Binding
	Biological Process	Microtubule Nucleation Anterograde Axon Cargo Transport Positive Regulation Of Cell Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Neuron Projection Development Melanosome Organization Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Anterograde Synaptic Vesicle Transport Platelet Dense Granule Organization Mitochondrial Outer Membrane Permeabilization
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: APP BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 FAM9B HMOX2 MEST PAM16 RDH11 SNAPIN TNNT1 WASH1	41 interactors: AAMP ALAS1 APP BLOC1S2 BRD4 CEP70 CRELD2 DVL3 EDRF1 EPS8 FAM9B FEZ1 FST FYN GIT1 GPRASP1 HAP1 HMBOX1 IKZF1 IMMT KBTBD7 KCTD6 KRTAP10-7 LZTS2 MDFI MRFAP1 NGEF NOL7 PI4KA PNMA1 RASSF1 SF3B2 TAOK1 TRIM23 TUBA1A TUBB2B WIZ ZC3H15 ZFP28 ZNF205 ZNF331
Entrez ID		282991	65265
HPRD ID		12526	07951
Ensembl ID			ENSG00000182307
Uniprot IDs		F1T0F0 Q6QNY1	Q9H7E9
PDB IDs
Enriched GO Terms of Interacting Partners?		Anterograde Synaptic Vesicle Transport Axon Cargo Transport Melanosome Organization Pigment Granule Organization Anterograde Axon Cargo Transport Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Cellular Pigmentation Synaptic Vesicle Transport Pigmentation Microtubule-based Movement Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Pigment Granule Maturation Endosome To Melanosome Transport Establishment Of Organelle Localization Intracellular Transport Cellular Pigment Accumulation Organelle Localization Microtubule-based Process Endosomal Transport Neuron Projection Development Establishment Of Localization In Cell Post-Golgi Vesicle-mediated Transport Vesicle-mediated Transport Movement Of Cell Or Subcellular Component Neuron Development Synaptic Transmission Cellular Localization Neuron Differentiation Cell Projection Organization Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Secretion Of Lysosomal Enzymes Cell-cell Signaling Secretion By Cell Developmental Pigmentation Generation Of Neurons Neurogenesis Golgi Vesicle Transport Platelet Dense Granule Organization Secretion Cell Development Positive Regulation Of Pigment Cell Differentiation Cytoplasmic Transport Transport Exocytosis	Cell Cycle Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Positive Regulation Of Metabolic Process Cytoskeleton-dependent Intracellular Transport Regulation Of Signaling Axon Cargo Transport Regulation Of Cell Cycle Process Positive Regulation Of Mitotic Cell Cycle Phase Transition Positive Regulation Of Cell Cycle Phase Transition Mitotic Cell Cycle Cell Cycle Process Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Axon Guidance Positive Regulation Of Cell Cycle Process Locomotion Positive Regulation Of Signal Transduction Ephrin Receptor Signaling Pathway Regulation Of Cellular Process Regulation Of Cell Morphogenesis Protein Polymerization Regulation Of Metabolic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of JNK Cascade Positive Regulation Of Cell Cycle Microtubule-based Process Anterograde Axon Cargo Transport Positive Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Axonogenesis Microtubule-based Transport Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Neuron Projection Development Intracellular Signal Transduction Cell Projection Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation System Development Cellular Protein Complex Assembly Generation Of Neurons Positive Regulation Of Neutrophil Differentiation Positive Regulation Of Neurotrophin Production Positive Regulation Of Nonmotile Primary Cilium Assembly Positive Regulation Of Hydrogen Peroxide Biosynthetic Process Signal Transduction Chemotaxis Enzyme Linked Receptor Protein Signaling Pathway
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