BLOC1S2

Name	biogenesis of lysosomal organelles complex 1 subunit 2
Structure	No pdb structure
Interactors	36 interactors: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 TTC3 WASHC1 WASHC3
GO Annotations	Cellular Component	Gamma-tubulin Complex Nucleus Cytoplasm Mitochondrion Lysosome Lysosomal Membrane Centrosome Cytosol Cytoskeleton Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm
	Molecular Function	Protein Binding Gamma-tubulin Binding
	Biological Process	Microtubule Nucleation Anterograde Axonal Transport Positive Regulation Of Cell Population Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Positive Regulation Of DNA-templated Transcription Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Platelet Dense Granule Organization Regulation Of Lysosome Size Organelle Transport Along Microtubule Mitochondrial Outer Membrane Permeabilization
GWAS	Refractive error ( 32231278 )
Entrez ID	282991
HPRD ID	12526
Ensembl ID	ENSG00000196072
Uniprot IDs	A0A087X1N6 F1T0F0 Q6QNY1
PDB IDs	Not available
GO Terms Enriched among Interactors ?	Anterograde Synaptic Vesicle Transport BLOC-1 Complex Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Axo-dendritic Transport Anterograde Axonal Transport Vesicle Transport Along Microtubule Vesicle Cytoskeletal Trafficking Establishment Of Vesicle Localization Axon Cytoplasm Axonal Transport Vesicle Localization Organelle Localization Organelle Transport Along Microtubule Intracellular Transport Transport Along Microtubule Melanosome Transport Cellular Localization Establishment Of Melanosome Localization Pigment Granule Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Melanosome Localization Pigment Granule Localization Vesicle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Microtubule-based Transport Microvesicle Regulation Of Actin Nucleation Plasma Membrane Bounded Cell Projection Organization Endosome To Melanosome Transport Microtubule-based Movement Establishment Of Organelle Localization Protein Transport Cell Projection Organization Secretion By Cell Organelle Organization Membrane Curvature Sensor Activity Microtubule-based Process Establishment Of Protein Localization Secretion Of Lysosomal Enzymes Neuron Projection Development Exocytosis Positive Regulation Of Pigment Cell Differentiation Secretion Regulation Of Lysosome Size BORC Complex Positive Regulation Of Developmental Pigmentation Pigmentation