BLOC1S2 and BLOC1S4

Number of citations: 0 (PubMedID 15102850)
Data Source: HPRD (two hybrid)

		BLOC1S2	BLOC1S4
Name		biogenesis of lysosomal organelles complex 1 subunit 2	biogenesis of lysosomal organelles complex 1 subunit 4
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Gamma-tubulin Complex Nucleus Cytoplasm Mitochondrion Lysosome Lysosomal Membrane Centrosome Cytosol Cytoskeleton Membrane BLOC-1 Complex Cytoplasmic Side Of Lysosomal Membrane BORC Complex Axon Cytoplasm	Cytoplasm Cytosol BLOC-1 Complex Axon Cytoplasm
	Molecular Function	Protein Binding Gamma-tubulin Binding	Protein Binding
	Biological Process	Microtubule Nucleation Anterograde Axonal Transport Positive Regulation Of Cell Population Proliferation Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Endosomal Transport Neuron Projection Development Lysosome Localization Melanosome Organization Positive Regulation Of DNA-templated Transcription Anterograde Synaptic Vesicle Transport Regulation Of Endosome Size Platelet Dense Granule Organization Regulation Of Lysosome Size Organelle Transport Along Microtubule Mitochondrial Outer Membrane Permeabilization	Anterograde Axonal Transport Neuron Projection Development Melanosome Organization Anterograde Synaptic Vesicle Transport Neuromuscular Process Controlling Balance Platelet Aggregation
Pathways		None	Golgi Associated Vesicle Biogenesis
GWAS		Refractive error ( 32231278 )	No GWAS studies recorded
Interacting Genes		36 interacting genes: APP ARFIP2 BFSP2 BLOC1S1 BLOC1S3 BLOC1S4 BLOC1S5 BLOC1S6 C8orf33 CCDC146 CCHCR1 CCNC CTNNA3 DCTN2 ERP27 EXOC8 FAM161B FAM9B GADD45G GEM HMOX2 KRT26 MEST P4HA3 PAM16 PICK1 RDH11 SH2D4A SNAPIN SSC5D STX2 TNNT1 TRIML2 TTC3 WASHC1 WASHC3	7 interacting genes: AIMP2 BLOC1S1 BLOC1S2 BLOC1S5 BLOC1S6 EPB42 SNAPIN
Entrez ID		282991	55330
HPRD ID		12526	12035
Ensembl ID		ENSG00000196072	ENSG00000186222
Uniprot IDs		A0A087X1N6 F1T0F0 Q6QNY1	Q9NUP1
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Anterograde Synaptic Vesicle Transport BLOC-1 Complex Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Axo-dendritic Transport Anterograde Axonal Transport Vesicle Transport Along Microtubule Vesicle Cytoskeletal Trafficking Establishment Of Vesicle Localization Axon Cytoplasm Axonal Transport Vesicle Localization Organelle Localization Organelle Transport Along Microtubule Intracellular Transport Transport Along Microtubule Melanosome Transport Cellular Localization Establishment Of Melanosome Localization Pigment Granule Transport Cytoskeleton-dependent Intracellular Transport Establishment Of Localization In Cell Melanosome Localization Pigment Granule Localization Vesicle Organization Regulation Of Arp2/3 Complex-mediated Actin Nucleation Microtubule-based Transport Microvesicle Regulation Of Actin Nucleation Plasma Membrane Bounded Cell Projection Organization Endosome To Melanosome Transport Microtubule-based Movement Establishment Of Organelle Localization Protein Transport Cell Projection Organization Secretion By Cell Organelle Organization Membrane Curvature Sensor Activity Microtubule-based Process Establishment Of Protein Localization Secretion Of Lysosomal Enzymes Neuron Projection Development Exocytosis Positive Regulation Of Pigment Cell Differentiation Secretion Regulation Of Lysosome Size BORC Complex Positive Regulation Of Developmental Pigmentation Pigmentation	Anterograde Synaptic Vesicle Transport BLOC-1 Complex Synaptic Vesicle Transport Melanosome Organization Pigment Granule Organization Vesicle Transport Along Microtubule Anterograde Axonal Transport Vesicle Cytoskeletal Trafficking Axon Cytoplasm Axonal Transport Axo-dendritic Transport Organelle Transport Along Microtubule Establishment Of Vesicle Localization Vesicle Localization Transport Along Microtubule Regulation Of Lysosome Size BORC Complex Microvesicle Cytoskeleton-dependent Intracellular Transport Microtubule-based Transport Regulation Of Endosome Size Cytoplasmic Side Of Lysosomal Membrane Establishment Of Organelle Localization Regulation Of Vesicle Size Vesicle Organization Microtubule-based Movement Organelle Localization Neuron Projection Development Lysosome Localization Positive Regulation Of Pigment Cell Differentiation Positive Regulation Of Developmental Pigmentation Microtubule-based Process Plasma Membrane Bounded Cell Projection Organization Endosome To Melanosome Transport Regulation Of Developmental Pigmentation Cell Projection Organization Intracellular Transport Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Platelet Dense Granule Organization Melanosome Localization Pigment Granule Localization Organelle Organization Cellular Localization Establishment Of Localization In Cell Regulation Of Cellular Component Size Pigmentation Secretory Granule Organization Lysosomal Membrane