ATXN2 and PLS3

Number of citations of the paper that reports this interaction (PMID 16115810)
21

Data Source:
HPRD (in vivo, two hybrid)

		ATXN2	PLS3
Gene Name		ataxin 2	plastin 3
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Polysome Cytoplasmic Stress Granule Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	RNA Binding Epidermal Growth Factor Receptor Binding Protein Binding Protein C-terminus Binding Poly(A) RNA Binding	Actin Binding Calcium Ion Binding
	Biological Process	Negative Regulation Of Receptor Internalization Regulation Of Translation RNA Metabolic Process Cerebellar Purkinje Cell Differentiation Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly Negative Regulation Of Multicellular Organism Growth Neuron Projection Morphogenesis Homeostasis Of Number Of Cells RNA Transport Neuromuscular Process	Bone Development
Pathways
Drugs
Diseases
GWAS		Beta-2 microglubulin plasma levels ( 23417110) Blood pressure ( 21909110) Celiac disease ( 18311140) Chronic kidney disease ( 20383146) Diastolic blood pressure ( 19430483) Hematocrit ( 19862010) Hypothyroidism ( 22493691) Red blood cell traits ( 23222517) Retinal vascular caliber ( 21060863) Urate levels ( 23263486)
Protein-Protein Interactions		19 interactors: ACTN1 ACTN2 ATXN1 BAG6 BIN1 CHGB GFI1B GOLGA6L5P IDH3B KIAA1279 LCP1 NCOA4 PABPC1 PLS3 RBFOX1 SH3GL2 SH3GL3 TDRD7 ZNRD1	2 interactors: APP ATXN2
Entrez ID		6311	5358
HPRD ID		03307	02133
Ensembl ID		ENSG00000204842	ENSG00000102024
Uniprot IDs		Q99700	B4DGB4 B4DPW9 B7Z6M1 P13797
PDB IDs		3KTR	1AOA 1WJO
Enriched GO Terms of Interacting Partners?		System Development Multicellular Organismal Development Anatomical Structure Development Focal Adhesion Assembly Developmental Process Adherens Junction Assembly Cell-substrate Junction Assembly Actin Filament Bundle Assembly Regulation Of Metabolic Process Platelet Degranulation Lipid Tube Assembly Adherens Junction Organization	Regulation Of Multicellular Organism Growth Neuromuscular Process Regulation Of Translation Regulation Of Developmental Growth Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Posttranscriptional Regulation Of Gene Expression Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Axon Choice Point Recognition Regulation Of Growth Neuron Remodeling Neuron Projection Morphogenesis Negative Regulation Of Receptor Internalization Cytoplasmic MRNA Processing Body Assembly Brain Development Cerebellar Purkinje Cell Differentiation Head Development Neuron Projection Development Cell Projection Morphogenesis Stress Granule Assembly Cell Part Morphogenesis Cerebellar Purkinje Cell Layer Morphogenesis Cellular Copper Ion Homeostasis Negative Regulation Of Multicellular Organism Growth Negative Regulation Of Receptor-mediated Endocytosis Neuron Development Central Nervous System Development Copper Ion Homeostasis Suckling Behavior Cell Morphogenesis Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Cerebellar Cortex Formation Neuron Differentiation Cell Projection Organization Neurological System Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Cell Differentiation In Hindbrain Regulation Of Receptor Internalization Mating Behavior Cerebellar Purkinje Cell Layer Development Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Homeostatic Process Cerebellar Cortex Morphogenesis
Tagcloud ?		accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive
Tagcloud (Difference) ?		accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive
Tagcloud (Intersection) ?