ATXN2

Name ataxin 2
Structure PDB 3KTR
Novel Interactors 1 novel interactors: IMPDH2
Interactors 23 interactors: ACTN1 ACTN2 ATXN1 BAG6 BIN1 CEBPA CHGB GFI1B GOLGA6L5P IDH3B KIFBP LCP1 MIR128-1 MIR34B MIR7-1 NCOA4 PABPC1 PLS3 POLR1H RBFOX1 SH3GL2 SH3GL3 TDRD7
GO Annotations Cellular Component
Molecular Function
Biological Process
Diseases
GWAS
  • Aging traits (healthspan, parental lifespan or longevity) (multivariate analysis) ( 32678081 )
  • Allergic disease (asthma, hay fever and/or eczema) (age of onset) ( 32603359 )
  • Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis) ( 32603359 )
  • Allergic disease (asthma, hay fever or eczema) ( 29083406 )
  • Allergic rhinitis ( 30013184 31361310 )
  • Alopecia areata ( 25608926 )
  • Apolipoprotein B levels ( 32203549 )
  • Arthritis (juvenile idiopathic) ( 33106285 )
  • Asthma ( 30929738 32296059 )
  • Asthma (age of onset) ( 31036433 )
  • Asthma (childhood onset) ( 30929738 31036433 )
  • Asthma onset (childhood vs adult) ( 30929738 )
  • Beta-2 microglubulin plasma levels ( 23417110 )
  • Blood osmolality (transformed sodium) ( 28360221 )
  • Blood pressure ( 21909110 )
  • Body mass index ( 26426971 )
  • Body mass index and coronary artery disease (pairwise) ( 33619380 )
  • Body mass index and HDL-C (pairwise) ( 33619380 )
  • Body mass index and systole blood pressure (pairwise) ( 33619380 )
  • Caffeine consumption from coffee or tea ( 33287642 )
  • Celiac disease ( 18311140 22057235 )
  • Chronic kidney disease ( 20383146 )
  • Coronary artery disease ( 29212778 )
  • Crohn's disease ( 26192919 28067908 )
  • Diastolic blood pressure ( 19430483 26390057 27736895 )
  • Diastolic blood pressure (cigarette smoking interaction) ( 29455858 )
  • Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962 )
  • Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962 )
  • Diastolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858 )
  • Diastolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858 )
  • Eosinophil count ( 27863252 32888494 )
  • Eosinophil percentage of granulocytes ( 27863252 )
  • Eosinophil percentage of white cells ( 27863252 32888494 )
  • Estimated glomerular filtration rate ( 31015462 31152163 )
  • Gastroesophageal reflux disease ( 31527586 )
  • Glaucoma (primary open-angle) ( 26752265 33627673 )
  • Glomerular filtration rate (cystatin C) ( 28452372 )
  • Glycated hemoglobin levels ( 28898252 )
  • HDL cholesterol ( 30275531 )
  • Heart failure ( 31919418 )
  • Hematocrit ( 19862010 )
  • High light scatter reticulocyte count ( 27863252 )
  • High light scatter reticulocyte percentage of red cells ( 27863252 )
  • Hypertension ( 31879980 )
  • Hypothyroidism ( 22493691 27182965 )
  • Immature fraction of reticulocytes ( 27863252 )
  • Inflammatory bowel disease ( 26192919 28067908 )
  • Intraocular pressure ( 30054594 )
  • Juvenile idiopathic arthritis (oligoarticular or rheumatoid factor-negative polyarticular) ( 23603761 )
  • LDL cholesterol ( 30275531 )
  • LDL cholesterol levels ( 32203549 )
  • Left ventricle diastolic internal dimension ( 28394258 )
  • Liver enzyme levels (alkaline phosphatase) ( 33972514 )
  • Low density lipoprotein cholesterol levels ( 32154731 )
  • Lymphocyte percentage of white cells ( 32888494 )
  • Mean arterial pressure ( 27618448 )
  • Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962 )
  • Mean corpuscular hemoglobin ( 32888494 )
  • Mean corpuscular volume ( 27863252 32888494 )
  • Mean platelet volume ( 32888494 )
  • Mean reticulocyte volume ( 32888494 )
  • Mean spheric corpuscular volume ( 32888494 )
  • Monocyte count ( 27863252 )
  • Myeloproliferative neoplasms ( 33057200 )
  • Myocardial infarction ( 30226566 33532862 )
  • Neutrophil count ( 32888494 )
  • Neutrophil percentage of granulocytes ( 27863252 )
  • Neutrophil percentage of white cells ( 32888494 )
  • Parental lifespan ( 30642433 )
  • Parental longevity (combined parental age at death) ( 29227965 )
  • Parental longevity (combined parental attained age, Martingale residuals) ( 29227965 )
  • Parental longevity (father's age at death) ( 29227965 )
  • Parental longevity (father's attained age) ( 29227965 )
  • Parental longevity (mother's attained age) ( 29227965 )
  • Peripheral artery disease ( 25009551 )
  • Platelet count ( 24026423 27863252 29403010 32888494 33545615 )
  • Platelet distribution width ( 27863252 )
  • Plateletcrit ( 27863252 32888494 )
  • Primary biliary cholangitis ( 26394269 )
  • Primary biliary cirrhosis ( 22961000 )
  • Primary sclerosing cholangitis ( 23603763 )
  • Reaction time ( 29844566 )
  • Red blood cell count ( 32888494 )
  • Red blood cell traits ( 23222517 )
  • Reticulocyte fraction of red cells ( 27863252 )
  • Retinal vascular caliber ( 21060863 )
  • Sarcoidosis ( 26051272 )
  • Serum alkaline phosphatase levels ( 33547301 )
  • Serum total protein levels ( 29403010 )
  • Sjögren's syndrome ( 24097067 )
  • Smoking initiation ( 33082346 )
  • Smoking initiation (ever regular vs never regular) ( 30679032 )
  • Smoking status (ever vs never smokers) ( 30643258 )
  • Sum eosinophil basophil counts ( 27863252 )
  • Systemic lupus erythematosus ( 26502338 28714469 33272962 )
  • Systolic blood pressure (cigarette smoking interaction) ( 29455858 )
  • Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962 )
  • Systolic blood pressure x smoking status (current vs non-current) interaction (2df test) ( 29455858 )
  • Systolic blood pressure x smoking status (ever vs never) interaction (2df test) ( 29455858 )
  • Thyroid peroxidase antibody levels ( 24586183 )
  • Thyroid peroxidase antibody positivity ( 24586183 )
  • Total cholesterol levels ( 30275531 )
  • Urate levels ( 23263486 31578528 )
  • Vitiligo ( 27723757 )
  • White blood cell count ( 32888494 )
Entrez ID 6311
HPRD ID 03307
Ensembl ID ENSG00000204842
Uniprot IDs A0A5F9ZI57 F8VQP2 Q2M2R5 Q99700 V9GY86
PDB IDs 3KTR
GO Terms Enriched among Interactors ?