PLS3 and NRSN1

		PLS3	NRSN1
Description		plastin 3	neurensin 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Actin Filament Plasma Membrane Neuromuscular Junction Actin Filament Bundle	Membrane Transport Vesicle Growth Cone Cytoplasmic Vesicle Cell Projection Neuron Projection Neuronal Cell Body
	Molecular Function	Actin Binding Calcium Ion Binding Metal Ion Binding Actin Filament Binding Structural Constituent Of Presynaptic Actin Cytoskeleton	Protein Binding
	Biological Process	Actin Filament Bundle Assembly Actin Filament Network Formation Bone Development Regulation Of Synaptic Vesicle Cycle Presynaptic Actin Cytoskeleton Organization	Nervous System Development
Pathways
Drugs
Diseases
GWAS		Gestational age at birth (maternal effect) ( 28877031) Mean platelet volume ( 32888494) Platelet count ( 32888494) Platelet distribution width ( 32888494) Preterm birth (maternal effect) ( 28877031)	Alzheimer's disease in hypertension ( 31055733) Coronary artery disease ( 32469254) Information processing speed ( 21130836) Initial pursuit acceleration ( 29064472) Liver enzyme levels (alkaline phosphatase) ( 33972514) Periodontitis (Mean PAL) ( 24024966) Squamous cell lung carcinoma ( 28604730) Type 2 diabetes ( 31049640)
Interacting Genes		5 interacting genes: APP ATXN2 FILNC1 OGT SNCA	8 interacting genes: FATE1 FCGR1A GPA33 LYVE1 RNF24 SPACA1 SPINK1 TMEM106C
Entrez ID		5358	140767
HPRD ID		02133	18285
Ensembl ID		ENSG00000102024	ENSG00000152954
Uniprot IDs		B4DPW9 P13797	Q8IZ57
PDB IDs		1AOA 1WJO 7R94 7SX8 7SX9 7SXA
Enriched GO Terms of Interacting Partners?		Growth Cone Amyloid-beta Complex Regulation Of Synapse Assembly Growth Cone Lamellipodium Regulation Of Presynapse Organization Response To Copper Ion Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Response To Calcium Ion Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Neuron Differentiation Regulation Of Presynapse Assembly Regulation Of Protein Catabolic Process Amyloid Fibril Formation Regulation Of Neurotransmitter Uptake Microglial Cell Activation Regulation Of Generation Of Precursor Metabolites And Energy Leukocyte Activation Involved In Inflammatory Response Cellular Response To Copper Ion Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Cysteine-type Endopeptidase Inhibitor Activity Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Neuron Differentiation
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