ATXN2 and NCOA4

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		ATXN2	NCOA4
Gene Name		ataxin 2	nuclear receptor coactivator 4
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Golgi Apparatus Trans-Golgi Network Polysome Cytoplasmic Stress Granule Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm	Nucleus
	Molecular Function	RNA Binding Epidermal Growth Factor Receptor Binding Protein Binding Protein C-terminus Binding Poly(A) RNA Binding	Transcription Coactivator Activity Androgen Receptor Binding
	Biological Process	Negative Regulation Of Receptor Internalization Regulation Of Translation RNA Metabolic Process Cerebellar Purkinje Cell Differentiation Cytoplasmic MRNA Processing Body Assembly Stress Granule Assembly Negative Regulation Of Multicellular Organism Growth Neuron Projection Morphogenesis Homeostasis Of Number Of Cells RNA Transport Neuromuscular Process	Transcription, DNA-templated Male Gonad Development Response To Hormone Androgen Receptor Signaling Pathway Positive Regulation Of Transcription, DNA-templated
Pathways
Drugs
Diseases
GWAS		Beta-2 microglubulin plasma levels ( 23417110) Blood pressure ( 21909110) Celiac disease ( 18311140) Chronic kidney disease ( 20383146) Diastolic blood pressure ( 19430483) Hematocrit ( 19862010) Hypothyroidism ( 22493691) Red blood cell traits ( 23222517) Retinal vascular caliber ( 21060863) Urate levels ( 23263486)	Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978)
Protein-Protein Interactions		19 interactors: ACTN1 ACTN2 ATXN1 BAG6 BIN1 CHGB GFI1B GOLGA6L5P IDH3B KIAA1279 LCP1 NCOA4 PABPC1 PLS3 RBFOX1 SH3GL2 SH3GL3 TDRD7 ZNRD1	11 interactors: AKT1 AR ATXN2 ESR1 GTF2B KAT2B NR3C1 PPARG RNF14 RXRA VDR
Entrez ID		6311	8031
HPRD ID		03307	03584
Ensembl ID		ENSG00000204842	ENSG00000138293
Uniprot IDs		Q99700	B2R5V0 B4DF87 B4DZ85 Q13772 Q96E88
PDB IDs		3KTR	1T5Z
Enriched GO Terms of Interacting Partners?		System Development Multicellular Organismal Development Anatomical Structure Development Focal Adhesion Assembly Developmental Process Adherens Junction Assembly Cell-substrate Junction Assembly Actin Filament Bundle Assembly Regulation Of Metabolic Process Platelet Degranulation Lipid Tube Assembly Adherens Junction Organization	Transcription Initiation From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Intracellular Receptor Signaling Pathway Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Response To Hormone Cellular Response To Hormone Stimulus Cellular Response To Steroid Hormone Stimulus Cellular Response To Organic Cyclic Compound Positive Regulation Of Transcription, DNA-templated Response To Steroid Hormone Transcription From RNA Polymerase II Promoter Response To Organic Cyclic Compound Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Cellular Response To Lipid Intracellular Steroid Hormone Receptor Signaling Pathway Response To Lipid RNA Metabolic Process Maternal Process Involved In Female Pregnancy Regulation Of Gene Expression Gland Development Reproductive Structure Development Transcription, DNA-templated Reproductive System Development Cellular Nitrogen Compound Metabolic Process Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Mammary Gland Epithelium Development Response To Organic Substance Macromolecule Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Cellular Response To Organic Substance Developmental Process Involved In Reproduction Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Reproductive Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Positive Regulation Of Oxidoreductase Activity Mammary Gland Development Maternal Placenta Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive	androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 p44 pca promotion spliced suppressive switch switches tblr1 versions wdr77
Tagcloud (Difference) ?		accumulations als amyotrophic basophilic c9orf72 causative cohorts colocalization cord expansion expansions fused ggggcc granules hexanucleotide highlights inclusions indicative motor neuron pabp paralysis polyglutamine proteomic repeat sarcoma spinal tdp transactive	androgen androgens ar ara70 ara70alpha ara70beta art benign coactivator coactivators corepressor cytoplasmic dysregulation ele1 exhibiting inhibitions internally luciferase mep50 p44 pca promotion spliced suppressive switch switches tblr1 versions wdr77
Tagcloud (Intersection) ?