DDX39A and SARNP

Number of citations of the paper that reports this interaction (PubMedID 15338056)
41

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		DDX39A	SARNP
Description		DExD-box helicase 39A	SAP domain containing ribonucleoprotein
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Membrane Nuclear Speck	Transcription Export Complex Nucleus Nucleoplasm Nuclear Speck Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	Nucleotide Binding Nucleic Acid Binding RNA Binding RNA Helicase Activity MRNA Binding Helicase Activity Protein Binding ATP Binding Hydrolase Activity ATP Hydrolysis Activity Identical Protein Binding	DNA Binding Chromatin Binding RNA Binding Protein Binding
	Biological Process	MRNA Splicing, Via Spliceosome Toll-like Receptor Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway MRNA Processing RNA Export From Nucleus MRNA Export From Nucleus RNA Splicing Negative Regulation Of Innate Immune Response Negative Regulation Of RNA Export From Nucleus	Negative Regulation Of Transcription By RNA Polymerase II MRNA Export From Nucleus Regulation Of Translation Poly(A)+ MRNA Export From Nucleus MRNA Transport
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Immature fraction of reticulocytes ( 32888494) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494)	Kawasaki disease ( 33772158) Pulse pressure ( 27841878) Systolic blood pressure ( 27841878)
Interacting Genes		14 interacting genes: CCL14 CEBPA DDX39B EXOSC9 HIPK2 HNRNPLL PTK2 RNF4 SARNP SAT1 SUMO2 TERF1 TERF2IP UBE2I	9 interacting genes: CEBPA CSNK2B DAPK1 DDX39A DDX39B ESR1 EXOSC8 VHL YTHDF1
Entrez ID		10212	84324
HPRD ID		10861	16716
Ensembl ID		ENSG00000123136	ENSG00000205323
Uniprot IDs		O00148	P82979
PDB IDs		8IJU	2DO1
Enriched GO Terms of Interacting Partners?		PML Body Regulation Of Ubiquitin-dependent Protein Catabolic Process Nuclear Body Shelterin Complex Nuclear Telomere Cap Complex Telomere Capping G-rich Strand Telomeric DNA Binding Transcription Export Complex Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Nucleoplasm Regulation Of Primary Metabolic Process Macromolecule Metabolic Process Positive Regulation Of Proteolysis Involved In Protein Catabolic Process SUMO Transferase Activity RNA-templated DNA Biosynthetic Process Telomere Maintenance Via Telomerase Nuclear Export Regulation Of Proteolysis Nucleus Nuclear Chromosome Presynaptic Cytosol Postsynaptic Cytosol Telomere Maintenance Via Telomere Lengthening Telomeric DNA Binding Positive Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Telomere Maintenance Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Proteolysis Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Regulation Of Protein Metabolic Process RNA Binding Spermidine Binding Protein Sumoylation Negative Regulation Of Establishment Of Protein Localization To Telomere Negative Regulation Of Establishment Of Protein-containing Complex Localization To Telomere Negative Regulation Of Establishment Of RNA Localization To Telomere Positive Regulation Of Shelterin Complex Assembly SUMO Conjugating Enzyme Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of Chromosome Organization Regulation Of Metabolic Process Nuclear Transport Nucleocytoplasmic Transport Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process	Identical Protein Binding Negative Regulation Of Metabolic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Notch Signaling Pathway Chromatin Binding Nucleoplasm CHOP-C/EBP Complex RNA Metabolic Process Nucleus Regulation Of Macromolecule Metabolic Process Macromolecule Metabolic Process Negative Regulation Of Biosynthetic Process RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Chromatin Response To Vitamin B2 White Fat Cell Proliferation Positive Regulation Of RNA Metabolic Process Memory C/EBP Complex Protein Kinase CK2 Complex Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of NMDA Receptor Activity DAPK1-calmodulin Complex Positive Regulation Of Autophagic Cell Death Nuclear Estrogen Receptor Activity TFIIB-class Transcription Factor Binding Prostate Epithelial Cord Elongation Positive Regulation Of Nitric-oxide Synthase Activity Mammary Gland Branching Involved In Pregnancy Antral Ovarian Follicle Growth Helicase Activity RNA Export From Nucleus MRNA Export From Nucleus MRNA Transport Nuclear Export MRNA Binding RNA Helicase Activity Negative Regulation Of RNA Export From Nucleus U5 SnRNA 3'-end Processing U1 SnRNA 3'-end Processing Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Hematopoietic Stem Cell Proliferation Rb-E2F Complex Release From Viral Latency Regulation Of Branching Involved In Prostate Gland Morphogenesis Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Catabolic Process
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