DDX39A and HIPK2

Number of citations of the paper that reports this interaction (PMID 14667819)
24

Data Source:
HPRD (two hybrid)

		DDX39A	HIPK2
Gene Name		DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A	homeodomain interacting protein kinase 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Membrane	Nucleus Cytoplasm Nuclear Body PML Body RNA Polymerase II Transcription Factor Complex
	Molecular Function	Helicase Activity Protein Binding ATP Binding Poly(A) RNA Binding	RNA Polymerase II Activating Transcription Factor Binding RNA Polymerase II Transcription Coactivator Activity Transcription Corepressor Activity Protein Kinase Activity Protein Serine/threonine Kinase Activity Protein Binding ATP Binding SMAD Binding Virion Binding
	Biological Process	MRNA Splicing, Via Spliceosome MRNA Export From Nucleus	Negative Regulation Of Transcription From RNA Polymerase II Promoter Eye Development Positive Regulation Of Protein Phosphorylation Transcription, DNA-templated Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Transforming Growth Factor Beta Receptor Signaling Pathway Smoothened Signaling Pathway Adult Walking Behavior Positive Regulation Of Cell Proliferation Anterior/posterior Pattern Specification Retina Layer Formation Peptidyl-serine Phosphorylation Peptidyl-threonine Phosphorylation Modulation By Virus Of Host Morphology Or Physiology Neuron Differentiation Erythrocyte Differentiation Positive Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of BMP Signaling Pathway PML Body Organization Positive Regulation Of Protein Binding Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Positive Regulation Of DNA Binding Negative Regulation Of Neuron Apoptotic Process Positive Regulation Of Angiogenesis Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of JNK Cascade Embryonic Camera-type Eye Morphogenesis Voluntary Musculoskeletal Movement Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Cell Cycle Embryonic Retina Morphogenesis In Camera-type Eye Lens Induction In Camera-type Eye SMAD Protein Signal Transduction Iris Morphogenesis Cellular Response To Hypoxia Intrinsic Apoptotic Signaling Pathway
Pathways			Generic Transcription Pathway YAP1- and WWTR1 (TAZ)-stimulated gene expression
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: CCL14 DDX39B EXOSC9 HIPK2 PTK2 SARNP SAT1 TERF1 TERF2 TERF2IP	48 interactors: AATF BTRC CHMP4B CREBBP CUL1 CXCL1 DAXX DDX39A DDX39B EP300 FBXW7 HIST2H2BE HMGA1 KAT2B MAP3K7 MBP MDM2 MECP2 MKNK1 MYB MYBL1 NKX2-1 NKX2-5 NKX3-1 NLK PAX6 PML PTCH1 RANBP9 RUNX1 SENP1 SIAH1 SIAH2 SKI SMAD1 SMAD2 SMAD3 SP100 SUMO1 SUMO2 TP53 TP53INP1 TP63 TP73 TRADD UBE2I WSB1 ZBTB4
Entrez ID		10212	28996
HPRD ID		10861	06039
Ensembl ID		ENSG00000123136	ENSG00000064393
Uniprot IDs		O00148	Q9H2X6
PDB IDs
Enriched GO Terms of Interacting Partners?		Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance RNA-dependent DNA Replication Negative Regulation Of Telomere Maintenance Via Semi-conservative Replication Telomere Maintenance Via Telomere Lengthening Telomeric Loop Formation Age-dependent Telomere Shortening Telomere Maintenance Via Telomere Shortening Protection From Non-homologous End Joining At Telomere Telomere Capping Protein Localization To Chromosome, Telomeric Region Telomere Maintenance Replicative Cell Aging Negative Regulation Of Chromosome Organization Regulation Of Nuclear Cell Cycle DNA Replication Negative Regulation Of DNA Metabolic Process Nucleobase-containing Compound Metabolic Process Protein Localization To Chromosome Regulation Of Chromosome Organization Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Homeostatic Process DNA Replication Negative Regulation Of DNA Replication Nitrogen Compound Metabolic Process MRNA Export From Nucleus Regulation Of Organelle Organization Regulation Of Cell Cycle Cell Aging RNA Export From Nucleus Negative Regulation Of DNA Recombination At Telomere Regulation Of Cellular Component Organization Negative Regulation Of Cell Cycle Spermidine Acetylation Regulation Of Cell Cycle Process Regulation Of Cellular Process Nuclear Export MRNA Transport RNA Secondary Structure Unwinding Putrescine Catabolic Process Regulation Of DNA Replication Regulation Of Response To DNA Damage Stimulus RNA Transport Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of DNA Damage Checkpoint Voluntary Musculoskeletal Movement Netrin-activated Signaling Pathway Nuclear Polyadenylation-dependent RRNA Catabolic Process	Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Viral Process Response To Organic Substance Apoptotic Process Transcription, DNA-templated Cellular Response To Organic Substance Tube Development Regulation Of Signaling Programmed Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Cell Death Regulation Of Protein Metabolic Process Response To Stimulus Cell Death Death Regulation Of Signal Transduction Negative Regulation Of Cell Proliferation Regulation Of Apoptotic Process Regulation Of Cell Proliferation Cell Cycle RNA Metabolic Process Regulation Of Cellular Protein Metabolic Process Transcription From RNA Polymerase II Promoter Cell Cycle Process Regulation Of Cell Cycle Cell Communication Gene Expression Apoptotic Signaling Pathway Positive Regulation Of Apoptotic Signaling Pathway
Tagcloud ?			adding complexity decisions determines e3 fail fate favoring feedback finger homeodomain inactivated interferes ligase loop preferentially proline siah2 stimulates switch termination ubiquitin ubiquitination uncovers waf1 xaf1 xiap zinc znf313
Tagcloud (Difference) ?			adding complexity decisions determines e3 fail fate favoring feedback finger homeodomain inactivated interferes ligase loop preferentially proline siah2 stimulates switch termination ubiquitin ubiquitination uncovers waf1 xaf1 xiap zinc znf313
Tagcloud (Intersection) ?