S100A2 and FKBP4

Number of citations of the paper that reports this interaction (PMID 20188096)
7

Data Source:
BioGRID (pull down, affinity chromatography technology)

		S100A2	FKBP4
Gene Name		S100 calcium binding protein A2	FK506 binding protein 4, 59kDa
Image
Gene Ontology Annotations	Cellular Component	Cellular_component	Nucleoplasm Cytoplasm Mitochondrion Endoplasmic Reticulum Membrane Cytosol Microtubule Neuronal Cell Body Axonal Growth Cone Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding ATP Binding GTP Binding FK506 Binding Protein Binding, Bridging Heat Shock Protein Binding Copper-dependent Protein Binding Glucocorticoid Receptor Binding Poly(A) RNA Binding Tau Protein Binding Phosphoprotein Binding
	Biological Process	Endothelial Cell Migration	Protein Peptidyl-prolyl Isomerization Protein Folding Steroid Hormone Receptor Complex Assembly Copper Ion Transport Embryo Implantation Negative Regulation Of Neuron Projection Development Androgen Receptor Signaling Pathway Prostate Gland Development Negative Regulation Of Microtubule Polymerization Or Depolymerization Negative Regulation Of Microtubule Polymerization Protein Complex Localization Cellular Response To Heat Male Sex Differentiation Chaperone-mediated Protein Folding Regulation Of Cellular Response To Heat
Pathways			HSF1-dependent transactivation Attenuation phase Cellular response to heat stress
Drugs
Diseases
GWAS			Quantitative traits ( 19197348)
Protein-Protein Interactions		11 interactors: FKBP4 MDM2 PPID S100A1 S100B S100P STUB1 TP53 TPM1 TPM2 TPM3	25 interactors: ACVR1 ATOX1 CALM1 CSNK2A1 EGFR ESR1 FES FKBP1A GLMN HSF1 HSP90AA1 HSPA4 IRF4 NR3C1 NR3C2 PHYH PTPN2 S100A1 S100A2 S100A6 SH3BP4 SMURF2 SNCA SQSTM1 STIP1
Entrez ID		6273	2288
HPRD ID		01508	11794
Ensembl ID		ENSG00000196754
Uniprot IDs		P29034	Q02790
PDB IDs		2RGI 4DUQ	1N1A 1P5Q 1Q1C 1QZ2 4DRJ 4LAV 4LAW 4LAX
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Cellular Response To UV Actin Filament-based Movement Cellular Response To Light Stimulus Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Cellular Response To Stress Response To UV Cellular Response To Radiation Response To Abiotic Stimulus Cellular Response To Oxidative Stress Muscle Contraction Regulation Of ATPase Activity Regulation Of Signal Transduction By P53 Class Mediator Muscle System Process Positive Regulation Of Transport DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Hypoxia Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Response To Antibiotic Positive Regulation Of Cellular Component Biogenesis Chaperone-mediated Protein Folding Regulation Of Protein Complex Assembly Response To Light Stimulus Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Steroid Hormone Receptor Complex Assembly Positive Regulation Of Heart Rate By Epinephrine Cellular Response To UV-C Cellular Response To Vitamin B1 Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Peptidyl-prolyl Isomerization Signal Transduction In Response To DNA Damage Response To Oxidative Stress Regulation Of Cell Cycle Arrest Mitotic DNA Damage Checkpoint Protein Complex Assembly Negative Regulation Of Macromitophagy Positive Regulation Of Voltage-gated Calcium Channel Activity	Response To Organic Substance Cellular Response To Organic Substance Regulation Of Oxidoreductase Activity Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Response To Stimulus Regulation Of Nitric-oxide Synthase Activity Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Metabolic Process Regulation Of Reactive Oxygen Species Biosynthetic Process Cellular Response To Stimulus Cellular Response To Steroid Hormone Stimulus Negative Regulation Of Signal Transduction Regulation Of Signal Transduction Response To Lipid Cellular Response To Growth Factor Stimulus Negative Regulation Of Signaling Response To Organic Cyclic Compound Response To Growth Factor Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Phospholipase Activity Developmental Process System Development Positive Regulation Of Protein Metabolic Process Cellular Response To Organic Cyclic Compound Signaling Regulation Of Signaling Regulation Of Immune System Process Cell Communication Defense Response Protein Import Into Mitochondrial Outer Membrane Response To Steroid Hormone Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Oxidoreductase Activity Response To Stress Regulation Of Cell Proliferation Positive Regulation Of Nitric Oxide Biosynthetic Process Multicellular Organismal Development Positive Regulation Of Reactive Oxygen Species Biosynthetic Process Innate Immune Response Cellular Response To Glucocorticoid Stimulus Response To Glucocorticoid Anatomical Structure Development Cellular Response To Corticosteroid Stimulus Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Response To Hormone Stimulus Regulation Of Immune Response Response To Corticosteroid
Tagcloud ?		carcinogenesis concept conflicting correlate cytoplasm debated disagree distributed downregulated dual ef equally hountis indicative indicator location middle movement nsclc operable positivity precise published seem stages substantial unfavorable varies
Tagcloud (Difference) ?		carcinogenesis concept conflicting correlate cytoplasm debated disagree distributed downregulated dual ef equally hountis indicative indicator location middle movement nsclc operable positivity precise published seem stages substantial unfavorable varies
Tagcloud (Intersection) ?