S100A2 and TPM2

Number of citations of the paper that reports this interaction (PMID 9092943)
2

Data Source:
HPRD (in vitro, in vivo)

		S100A2	TPM2
Gene Name		S100 calcium binding protein A2	tropomyosin 2 (beta)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cellular_component	Cytosol Muscle Thin Filament Tropomyosin
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding	Actin Binding Structural Constituent Of Muscle
	Biological Process	Endothelial Cell Migration	Muscle Contraction Muscle Filament Sliding Regulation Of ATPase Activity
Pathways			Striated Muscle Contraction Smooth Muscle Contraction
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: FKBP4 MDM2 PPID S100A1 S100B S100P STUB1 TP53 TPM1 TPM2 TPM3	11 interactors: ACTA1 ACTB ADRBK1 JUN PDLIM7 PIK3CG RRAD S100A2 S100A4 SKIL TPM1
Entrez ID		6273	7169
HPRD ID		01508	11768
Ensembl ID		ENSG00000196754	ENSG00000198467
Uniprot IDs		P29034	A7XZE4 P07951 Q5TCU3
PDB IDs		2RGI 4DUQ
Enriched GO Terms of Interacting Partners?		Actin-myosin Filament Sliding Muscle Filament Sliding Actin-mediated Cell Contraction Cellular Response To UV Actin Filament-based Movement Cellular Response To Light Stimulus Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Cellular Response To Stress Response To UV Cellular Response To Radiation Response To Abiotic Stimulus Cellular Response To Oxidative Stress Muscle Contraction Regulation Of ATPase Activity Regulation Of Signal Transduction By P53 Class Mediator Muscle System Process Positive Regulation Of Transport DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Hypoxia Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Response To Antibiotic Positive Regulation Of Cellular Component Biogenesis Chaperone-mediated Protein Folding Regulation Of Protein Complex Assembly Response To Light Stimulus Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Mitotic G1 DNA Damage Checkpoint Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Steroid Hormone Receptor Complex Assembly Positive Regulation Of Heart Rate By Epinephrine Cellular Response To UV-C Cellular Response To Vitamin B1 Positive Regulation Of Proteasomal Protein Catabolic Process Positive Regulation Of Cell Cycle Arrest DNA Damage Response, Signal Transduction By P53 Class Mediator Protein Peptidyl-prolyl Isomerization Signal Transduction In Response To DNA Damage Response To Oxidative Stress Regulation Of Cell Cycle Arrest Mitotic DNA Damage Checkpoint Protein Complex Assembly Negative Regulation Of Macromitophagy Positive Regulation Of Voltage-gated Calcium Channel Activity	Negative Regulation Of Striated Muscle Contraction Multicellular Organismal Development Anatomical Structure Morphogenesis Negative Regulation Of Muscle Contraction Regulation Of Muscle Contraction Negative Regulation Of Heart Contraction Regulation Of Heart Contraction Anatomical Structure Formation Involved In Morphogenesis Developmental Process System Development Actin-myosin Filament Sliding Muscle Filament Sliding Organ Development Muscle Contraction Platelet Aggregation Endocytosis Actin-mediated Cell Contraction Muscle System Process Response To Wounding Cell Differentiation Muscle Organ Development Cardiac Muscle Contraction Anatomical Structure Development Movement Of Cell Or Subcellular Component Striated Muscle Tissue Development Innate Immune Response Actin Filament-based Movement Heart Contraction Muscle Tissue Development Cardiovascular System Development Positive Regulation Of Heart Rate By Epinephrine Negative Regulation Of The Force Of Heart Contraction By Chemical Signal Cellular Response To Potassium Ion Starvation Enzyme Linked Receptor Protein Signaling Pathway Myofibril Assembly Tissue Development Striated Muscle Contraction Regulation Of Striated Muscle Contraction Cell Development Leading Edge Cell Differentiation Skeletal Muscle Fiber Adaptation Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Actomyosin Structure Organization Natural Killer Cell Chemotaxis Muscle Structure Development Heart Development Immune System Process Negative Regulation Of Triglyceride Catabolic Process Neutrophil Extravasation Skeletal Muscle Tissue Development
Tagcloud ?		carcinogenesis concept conflicting correlate cytoplasm debated disagree distributed downregulated dual ef equally hountis indicative indicator location middle movement nsclc operable positivity precise published seem stages substantial unfavorable varies	3gamma caecum ck8 comparative crmp2 cytoskeleton decreasing desmin displaying evaluable extension grafting insight invasive locally muscularis nets neuroendocrine nude orthotopic propria proteomic proteomics si stc tcp1epsilon underline vimentin xenograft
Tagcloud (Difference) ?		carcinogenesis concept conflicting correlate cytoplasm debated disagree distributed downregulated dual ef equally hountis indicative indicator location middle movement nsclc operable positivity precise published seem stages substantial unfavorable varies	3gamma caecum ck8 comparative crmp2 cytoskeleton decreasing desmin displaying evaluable extension grafting insight invasive locally muscularis nets neuroendocrine nude orthotopic propria proteomic proteomics si stc tcp1epsilon underline vimentin xenograft
Tagcloud (Intersection) ?