S100A2 and ARL13B

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		S100A2	ARL13B
Description		S100 calcium binding protein A2	ARF like GTPase 13B
Image			No pdb structure
GO Annotations	Cellular Component		Cytoplasm Cytosol Cytoskeleton Plasma Membrane Cilium Axoneme Microtubule Cytoskeleton Membrane Motile Cilium Ciliary Basal Body Cell Projection Intercellular Bridge Ciliary Membrane Non-motile Cilium
	Molecular Function	Calcium Ion Binding Protein Binding Identical Protein Binding Metal Ion Binding Transition Metal Ion Binding Calcium-dependent Protein Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding
	Biological Process	Endothelial Cell Migration	Heart Looping Smoothened Signaling Pathway Determination Of Left/right Symmetry Dorsal/ventral Pattern Formation Neural Tube Patterning Interneuron Migration From The Subpallium To The Cortex Formation Of Radial Glial Scaffolds Cilium Assembly Left/right Axis Specification Receptor Localization To Non-motile Cilium Non-motile Cilium Assembly
Pathways			ARL13B-mediated ciliary trafficking of INPP5E RHOQ GTPase cycle RHOJ GTPase cycle Chaperone Mediated Autophagy Late endosomal microautophagy Aggrephagy Aggrephagy
Drugs		Olopatadine Calcium Zinc Copper Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases			Joubert syndrome
GWAS
Interacting Genes		16 interacting genes: ARL13B CEP20 EPO FAM209A FKBP4 MDM2 PPID S100A1 S100A3 S100B S100P STUB1 TP53 TPM1 TPM2 TPM3	146 interacting genes: ACSF2 AIG1 ALG3 ANKRD46 AOC3 AQP10 ARLN B4GALNT2 BMP10 BNIP3 BRICD5 BTN2A2 C14orf180 C1GALT1 C2CD2L CCDC167 CCL4 CCL4L2 CD151 CD302 CD53 CDIPT CFHR5 CLDN4 CLDN8 CLEC4G CLEC7A CLN6 CMTM3 CMTM7 COL8A2 CSGALNACT2 CTSA CXCL16 CYB561D2 EBP EMP1 ENTPD3 ERG28 FAXDC2 FDFT1 FKBP8 FUNDC2 FXYD6 GAD2 GIMAP1 GIMAP5 GJB2 GOSR2 GPR37L1 HMOX1 HMOX2 HOMER3 ICMT IGFBP5 INSIG2 ITGAM JAGN1 KCNJ2 KLRG1 LEPROTL1 LHFPL5 LPAR3 MAL2 MALL MMD MOSPD3 MUCL1 MYADML2 NAT8 NINJ2 NKG7 NRM NUCB2 ORMDL1 ORMDL3 PAEP PDZK1IP1 PGAP2 PKNOX1 PLN PLP1 PLP2 PLPP4 PLPPR2 PMP22 PNLIPRP1 PRB1 PTPN9 RTP2 RUSF1 S100A2 SACM1L SEMA4G SLC13A3 SLC2A5 SLC35A1 SLC35B1 SLC38A7 SLC39A2 SMAGP SMCO4 SPN STRIT1 STX1A STX7 STX8 TECR TEX264 TFRC THSD7A THSD7B TM6SF2 TMEM11 TMEM120B TMEM121 TMEM128 TMEM14B TMEM14C TMEM187 TMEM190 TMEM218 TMEM229B TMEM254 TMEM43 TMEM54 TMEM60 TMEM65 TMEM79 TMEM86B TMEM97 TMUB2 TNFRSF10C TNMD TRARG1 TSPO2 UBE2I VAMP1 VAMP2 VAMP3 VAMP4 VAMP5 VSTM1 WFDC2 YIPF6 ZDHHC15
Entrez ID		6273	200894
HPRD ID		01508	12334
Ensembl ID		ENSG00000196754	ENSG00000169379
Uniprot IDs		P29034 Q5RHS7 R4GN49	A0A7P0T892 A0A7P0T933 A0A7P0Z473 Q3SXY8
PDB IDs		2RGI 4DUQ
Enriched GO Terms of Interacting Partners?		Muscle Thin Filament Tropomyosin Calcium-dependent Protein Binding Cellular Response To Actinomycin D Response To Hypoxia Response To Decreased Oxygen Levels Tau Protein Binding Response To Actinomycin D Cellular Response To Decreased Oxygen Levels Cellular Response To Hypoxia Cellular Response To UV-C Response To Oxygen Levels Cellular Response To Oxygen Levels Heat Shock Protein Binding Protein Homodimerization Activity Cellular Response To Antibiotic Regulation Of Blood Circulation Cellular Response To UV Response To UV-C Identical Protein Binding S100 Protein Binding Actin Filament Regulation Of System Process Response To Salt Stress Cellular Response To Light Stimulus Transition Metal Ion Binding Cytoplasm System Process Cytoskeleton Disordered Domain Specific Binding Cellular Response To Gamma Radiation Response To UV Cytosol Regulation Of ATP-dependent Activity Peptidyl-prolyl Cis-trans Isomerase Activity Cellular Response To Radiation Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Response To Antibiotic Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Embryo Implantation Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Erythrocyte Apoptotic Process Steroid Hormone Receptor Complex Assembly Response To Formaldehyde Cellular Response To Vitamin B1 Regulation Of Heart Contraction DNA Damage Response, Signal Transduction By P53 Class Mediator Supramolecular Fiber Organization Hsp90 Protein Binding Hsp70 Protein Binding Regulation Of Mitophagy	Membrane Endoplasmic Reticulum Membrane Endoplasmic Reticulum SNARE Complex Protein Binding SNAP Receptor Activity SNARE Complex Assembly Plasma Membrane Vesicle Fusion Organelle Fusion Organelle Membrane Fusion Establishment Of Protein Localization To Plasma Membrane Endomembrane System Chloride Channel Inhibitor Activity Sterol Biosynthetic Process Bleb Assembly Heme Oxidation Heme Oxygenase (decyclizing) Activity Structural Constituent Of Myelin Sheath Membrane Fusion Specific Granule Membrane Establishment Of Protein Localization To Membrane Vesicle Organization Membrane Organization Myelination Axon Ensheathment Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II Complex Heme Metabolic Process SNARE Binding Identical Protein Binding Transport Vesicle Golgi To Plasma Membrane Protein Transport Lipid Metabolic Process Synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I Complex Synaptobrevin 2-SNAP-25-syntaxin-1a Complex Porphyrin-containing Compound Metabolic Process Lipid Homeostasis Intracellular Sphingolipid Homeostasis Negative Regulation Of Ceramide Biosynthetic Process
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