S100A10 and CBR3

Number of citations: 83 (PubMedID 35914814)
Data Source: BioGRID (two hybrid)

		S100A10	CBR3
Name		S100 calcium binding protein A10	carbonyl reductase 3
Structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex	Extracellular Space Nucleoplasm Cytoplasm Cytosol
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity Carbonyl Reductase (NADPH) Activity Protein Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor NADPH Binding
	Biological Process	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition
Pathways		Dissolution of Fibrin Clot	Phase I - Functionalization of compounds
Drugs		Phenethyl Isothiocyanate	None
GWAS		Asthma ( 31619474 ) Diverticular disease ( 30177863 ) Serum metabolite levels ( 33031748 ) Urinary metabolite levels in chronic kidney disease ( 29545352 ) Urinary metabolite ratios in chronic kidney disease ( 29545352 )	Blood protein levels ( 30072576 ) Lumbar spine bone mineral density ( 22504420 )
Interacting Genes		23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT	7 interacting genes: ARIH2 BICD2 RAB35 RANBP9 S100A10 SDCBP UBC
Entrez ID		6281	874
HPRD ID		00232	07222
Ensembl ID		ENSG00000197747	ENSG00000159231
Uniprot IDs		P60903	O75828 V9HW40
PDB IDs		1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH	2HRB
GO Terms Enriched among Interactors		Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding	Cytoskeletal Anchor Activity Plasma Membrane Apical Dendrite