S100A10 and TRPV6

Number of citations of the paper that reports this interaction (PubMedID 12660155)
44

Data Source:
HPRD (in vitro)

		S100A10	TRPV6
Description		S100 calcium binding protein A10	transient receptor potential cation channel subfamily V member 6
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex	Plasma Membrane Membrane Calcium Channel Complex
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding	Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair	Monoatomic Ion Transport Calcium Ion Transport Regulation Of Calcium Ion-dependent Exocytosis Monoatomic Ion Transmembrane Transport Parathyroid Hormone Secretion Response To Calcium Ion Calcium Ion Homeostasis Transmembrane Transport Calcium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane
Pathways		Dissolution of Fibrin Clot	TRP channels
Drugs		Phenethyl Isothiocyanate
Diseases
GWAS		Asthma ( 31619474) Diverticular disease ( 30177863) Serum metabolite levels ( 33031748) Urinary metabolite levels in chronic kidney disease ( 29545352) Urinary metabolite ratios in chronic kidney disease ( 29545352)	Alcoholic chronic pancreatitis ( 28754779) Anxiety ( 31906708) Cancer ( 29299148) Mastocytosis ( 32752121)
Interacting Genes		23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT	17 interacting genes: CALB1 CALM1 KRT40 KRTAP10-3 KRTAP10-5 KRTAP10-8 MDFI MID2 NEDD4 NOTCH2NLA PDE9A PNMA1 PRKCA PTPN1 S100A10 SNCA TRAF1
Entrez ID		6281	55503
HPRD ID		00232	05982
Ensembl ID		ENSG00000197747	ENSG00000165125
Uniprot IDs		P60903	Q9H1D0
PDB IDs		1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH	6BO8 6BO9 6BOA 6D7S 6D7T 6E2F 7K4A 7K4B 7K4C 7K4D 7K4E 7K4F 7S88 7S89 7S8B 7S8C 8FOA 8FOB 8SP8 9CUH 9CUI 9CUJ 9CUK
Enriched GO Terms of Interacting Partners?		Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding	Keratin Filament Intermediate Filament Regulation Of Synaptic Plasticity Regulation Of Cell Communication Regulation Of Signaling Enzyme Binding Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Exocytosis Regulation Of Cell Junction Assembly Positive Regulation Of Cell Communication Positive Regulation Of Signaling Calyx Of Held Regulation Of Signal Transduction Regulation Of Synapse Organization Calcium Ion Binding Presynaptic Cytosol Postsynaptic Cytosol Transmembrane Transporter Binding Regulation Of Intracellular Signal Transduction Positive Regulation Of Synaptic Transmission Cellular Response To Fibroblast Growth Factor Stimulus Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Metanephric Connecting Tubule Development Terminal Bouton Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Presynaptic Endocytosis Protein-containing Complex Identical Protein Binding Protein Sequestering Activity Receptor Metabolic Process Formation Of Structure Involved In A Symbiotic Process Positive Regulation Of Cardiac Muscle Hypertrophy Regulation Of Synapse Assembly Regulation Of Exocytosis Response To Fibroblast Growth Factor Response To Desipramine Negative Regulation Of Norepinephrine Uptake Phospholipase D Inhibitor Activity Positive Regulation Of SNARE Complex Assembly Negative Regulation Of Dopamine Uptake Involved In Synaptic Transmission Phosphoprotein Binding Cytosol Modulation Of Chemical Synaptic Transmission Long-term Synaptic Potentiation Postsynapse Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Negative Regulation Of High Voltage-gated Calcium Channel Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Muscle System Process Regulation Of System Process
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