S100A10 and FSHR

Number of citations of the paper that reports this interaction (PMID 15196694)
8

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		S100A10	FSHR
Gene Name		S100 calcium binding protein A10	follicle stimulating hormone receptor
Image
Gene Ontology Annotations	Cellular Component	Extrinsic Component Of Plasma Membrane Membrane Raft Extracellular Vesicular Exosome	Plasma Membrane Integral Component Of Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Ion Channel Binding	Follicle-stimulating Hormone Receptor Activity Protein Binding
	Biological Process	Membrane Raft Assembly Membrane Budding Positive Regulation Of Rac GTPase Activity Positive Regulation Of Binding Protein Heterotetramerization Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Establishment Of Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading	G-protein Coupled Receptor Signaling Pathway Spermatogenesis Female Gamete Generation Gonad Development Male Gonad Development Female Gonad Development Follicle-stimulating Hormone Signaling Pathway
Pathways		Dissolution of Fibrin Clot Orphan transporters	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling G alpha (s) signalling events Class A/1 (Rhodopsin-like receptors) Hormone ligand-binding receptors Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs			Menotropins Follitropin beta Urofollitropin Choriogonadotropin alfa Suramin
Diseases
GWAS			Adverse response to chemotherapy (neutropenia/leucopenia) (etoposide) ( 23648065) Erectile dysfunction and prostate cancer treatment ( 20932654) Polycystic ovary syndrome ( 22885925 21151128) Radiation response ( 20923822)
Protein-Protein Interactions		13 interactors: ANXA2 ANXA7 BAD CDK16 COPS6 CTSB FSHR KCNK3 PLA2G4C PLG SETDB1 TRPV5 TRPV6	20 interactors: ADRBK1 AKT2 APPL1 ARR3 CANX CBX5 FSHB GRK4 GRK6 RNR2 RPS27A S100A10 TOP1 TOP1MT TUG1 UBA52 UBB UBC YWHAQ ZBTB16
Entrez ID		6281	2492
HPRD ID		00232	00639
Ensembl ID		ENSG00000197747	ENSG00000170820
Uniprot IDs		P60903	F5GZW2 P23945
PDB IDs		1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH	1XUN 1XWD 4AY9
Enriched GO Terms of Interacting Partners?		Fibrinolysis Negative Regulation Of Blood Coagulation Negative Regulation Of Coagulation Negative Regulation Of Wound Healing Cellular Homeostasis Reproductive Process Regulation Of Insulin Secretion Involved In Cellular Response To Glucose Stimulus Cellular Calcium Ion Homeostasis Homeostatic Process Calcium Ion Homeostasis Cellular Response To Chromate Response To Metal Ion Extracellular Matrix Organization Extracellular Structure Organization Chemical Homeostasis Regulation Of Blood Coagulation Positive Regulation Of Mitochondrial Membrane Potential Suppression By Virus Of Host Apoptotic Process Extracellular Matrix Disassembly Cellular Metal Ion Homeostasis Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Anatomical Structure Development Protein Tetramerization Cellular Cation Homeostasis Mononuclear Cell Migration Cellular Response To Oxygen Levels Cellular Ion Homeostasis Response To Calcium Ion Catabolic Process Metal Ion Homeostasis Regulation Of Wound Healing Response To Inorganic Substance Reproductive Structure Development Reproductive System Development Negative Regulation Of Cell-cell Adhesion Mediated By Cadherin Positive Regulation Of Apoptotic Process By Virus Glucose Catabolic Process Positive Regulation Of Fibrinolysis Cellular Response To Inorganic Substance Positive Regulation Of Type B Pancreatic Cell Development Follicle-stimulating Hormone Signaling Pathway Cellular Chemical Homeostasis Single Organism Reproductive Process Establishment Of Localization In Cell Organ Development System Development Developmental Process Ion Homeostasis Positive Regulation Of Glucokinase Activity	Glycogen Biosynthetic Process Viral Protein Processing Cellular Polysaccharide Biosynthetic Process Polysaccharide Biosynthetic Process Glycogen Metabolic Process Notch Receptor Processing Virion Assembly Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Polysaccharide Metabolic Process Intracellular Transport Of Virus Regulation Of Cell Cycle Arrest Programmed Cell Death Cell Death Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Death Negative Regulation Of Type I Interferon Production Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of ERBB Signaling Pathway Energy Reserve Metabolic Process Transforming Growth Factor Beta Receptor Signaling Pathway Glucose Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress Rhythmic Process Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Regulation Of DNA-templated Transcription In Response To Stress Carbohydrate Biosynthetic Process Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint I-kappaB Kinase/NF-kappaB Signaling Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Toll-like Receptor 2 Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Signal Transduction Involved In Cell Cycle Checkpoint Toll-like Receptor 9 Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Apoptotic Process Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Positive Regulation Of Programmed Cell Death Apoptotic Signaling Pathway Negative Regulation Of Ubiquitin-protein Transferase Activity
Tagcloud ?		annexin authentic baculovirus biochemical contained cytoskeleton derivatives display endocytic ii incorporation interference intestine lies mediating member mutants p11 porcine purified residue residues secretory ser serine spatial subjected substitutions	ancestral arose assigns booroola closely deer distance divergence duplication fecb fecundity fshrs gonadotrophin lh lhcgr lhcgrs linkage mammalian mammals ovine probes recombinants restriction rise sheep today tsh tshr
Tagcloud (Difference) ?		annexin authentic baculovirus biochemical contained cytoskeleton derivatives display endocytic ii incorporation interference intestine lies mediating member mutants p11 porcine purified residue residues secretory ser serine spatial subjected substitutions	ancestral arose assigns booroola closely deer distance divergence duplication fecb fecundity fshrs gonadotrophin lh lhcgr lhcgrs linkage mammalian mammals ovine probes recombinants restriction rise sheep today tsh tshr
Tagcloud (Intersection) ?