CBR3

Gene Name		carbonyl reductase 3
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytoplasm Cytosol
	Molecular Function	3-keto Sterol Reductase Activity Carbonyl Reductase (NADPH) Activity NADPH Binding
	Biological Process	Phylloquinone Catabolic Process Cognition Oxidation-reduction Process
Pathways
Drugs
Diseases
GWAS		Bone mineral density ( 22504420)
Protein-protein Interactions		4 interactors: ARIH2 RAB35 SDCBP UBC
Entrez ID		874
HPRD ID		07222
Ensembl ID		ENSG00000159231
Uniprot IDs		O75828
PDB IDs		2HRB
Enriched GO Terms of Interacting Partners?		Protein Polyubiquitination Endosomal Transport Ras Protein Signal Transduction Positive Regulation Of Extracellular Vesicular Exosome Assembly Antigen Processing And Presentation Regulation Of Extracellular Vesicular Exosome Assembly Intracellular Transport Plasma Membrane To Endosome Transport Protein Localization To Endosome Cell Development Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Viral Protein Processing Intracellular Signal Transduction Substrate-dependent Cell Migration, Cell Extension Positive Regulation Of MAPK Cascade Establishment Of Localization In Cell Hematopoietic Stem Cell Proliferation Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Immune System Process Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Protein Ubiquitination Cellular Response To Growth Factor Stimulus Response To Growth Factor Notch Receptor Processing Protein Modification By Small Protein Conjugation Protein Catabolic Process Endocytic Recycling Virion Assembly Cellular Localization Regulation Of MAPK Cascade Small GTPase Mediated Signal Transduction Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia Positive Regulation Of Organelle Assembly Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Cellular Response To Nerve Growth Factor Stimulus Glycogen Biosynthetic Process Intracellular Transport Of Virus Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Protein K63-linked Ubiquitination Substrate-dependent Cell Migration Protein K48-linked Ubiquitination Cellular Polysaccharide Biosynthetic Process Positive Regulation Of Intracellular Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Neuron Projection Development Polysaccharide Biosynthetic Process Cellular Macromolecule Catabolic Process
Tagcloud ?		abcb1 abcb5 abcc5 abcg2 adriamycin anthracycline caesius cardiomyopathy cbr1 comprehensively disposition doxorubicin fuelled glycoside individualizing maximize metabolizing neo peucetius pharmacogenetics pharmacogenomics polygenic pregnane pxr rlip76 slc22a16 streptomyces tailoring var