CBR3 and ATP5PO

Data Source: HiPPIP (Novel)

		CBR3	ATP5PO
Name		carbonyl reductase 3	ATP synthase peripheral stalk subunit OSCP
Structure
GO Annotations	Cellular Component	Extracellular Space Nucleoplasm Cytoplasm Cytosol	Nucleus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Cell Surface Membrane Proton-transporting ATP Synthase Complex
	Molecular Function	3-beta-hydroxysteroid 3-dehydrogenase (NADP+) Activity Carbonyl Reductase (NADPH) Activity Protein Binding NADPH Dehydrogenase (quinone) Activity Oxidoreductase Activity Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Oxidoreductase Activity, Acting On NAD(P)H, Quinone Or Similar Compound As Acceptor NADPH Binding	Protein Binding ATP Hydrolysis Activity Protein-containing Complex Binding Proton-transporting ATP Synthase Activity, Rotational Mechanism Estradiol Binding
	Biological Process	Xenobiotic Metabolic Process Phylloquinone Catabolic Process Cognition	ATP Biosynthetic Process Monoatomic Ion Transport Proton Motive Force-driven ATP Synthesis Proton Motive Force-driven Mitochondrial ATP Synthesis Cellular Response To CAMP Cellular Response To Cytokine Stimulus Proton Transmembrane Transport
Pathways		Phase I - Functionalization of compounds	Formation of ATP by chemiosmotic coupling Cristae formation Mitochondrial protein degradation
Drugs		None	Artenimol
GWAS		Blood protein levels ( 30072576 ) Lumbar spine bone mineral density ( 22504420 )	No GWAS studies recorded
Novel Interactors		10 novel interactors: ANK1 ATP5PO CLU IL10RB ITSN1 KCNE1 KCNJ15 PCP4 RCAN1 SHOX2	2 novel interactors: CBR3 RCAN1
Interacting Genes		7 interacting genes: ARIH2 BICD2 RAB35 RANBP9 S100A10 SDCBP UBC	19 interacting genes: APP CCDC136 CEP70 ERCC6 GOLGA2 HMBOX1 KRT13 KRT15 MIPOL1 NDC80 NME6 NT5C2 PNMA1 TEX13A TFIP11 TRIP6 USHBP1 ZBTB14 ZNF76
Entrez ID		874	539
HPRD ID		07222	02899
Ensembl ID		ENSG00000159231	ENSG00000241837
Uniprot IDs		O75828 V9HW40	P48047
PDB IDs		2HRB	8H9E 8H9I 8H9L 8H9P 8H9S 8H9T 8H9U 8H9V 8KI3
GO Terms Enriched among Interactors		Cytoskeletal Anchor Activity Plasma Membrane Apical Dendrite	Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining