S100A10 and NANOS2

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		S100A10	NANOS2
Name		S100 calcium binding protein A10	nanos C2HC-type zinc finger 2
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex	P-body Nucleus Cytoplasm Perinuclear Region Of Cytoplasm
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding	RNA Binding MRNA Binding Protein Binding Enzyme Activator Activity Zinc Ion Binding Metal Ion Binding
	Biological Process	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair	MRNA Catabolic Process Regulation Of Translation Spermatogenesis Negative Regulation Of Translation Cell Differentiation Germ-line Stem Cell Population Maintenance Negative Regulation Of Meiotic Nuclear Division Oogenesis MRNA Destabilization
Pathways		Dissolution of Fibrin Clot	None
Drugs		Phenethyl Isothiocyanate	None
GWAS		Asthma ( 31619474 ) Diverticular disease ( 30177863 ) Serum metabolite levels ( 33031748 ) Urinary metabolite levels in chronic kidney disease ( 29545352 ) Urinary metabolite ratios in chronic kidney disease ( 29545352 )	Asthma ( 31959851 )
Interacting Genes		23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT	4 interacting genes: CCNDBP1 MAGEA12 S100A10 SIAH1
Entrez ID		6281	339345
HPRD ID		00232	18784
Ensembl ID		ENSG00000197747	ENSG00000188425
Uniprot IDs		P60903	P60321
PDB IDs		1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH	Not available
GO Terms Enriched among Interactors		Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding	None