S100A10 and PLA2G4C

Number of citations: 0 (PubMedID 9202034)
Data Source: BioGRID (pull down)

		S100A10	PLA2G4C
Name		S100 calcium binding protein A10	phospholipase A2 group IVC
Structure			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex	Nuclear Envelope Nucleoplasm Mitochondrion Endoplasmic Reticulum Endoplasmic Reticulum Membrane Lipid Droplet Cytosol Plasma Membrane Cell Cortex Membrane Mitochondrial Membrane
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding	Phospholipase Activity Phosphatidylcholine Lysophospholipase Activity Phospholipase A2 Activity Calcium Ion Binding Protein Binding Phospholipid Binding Calcium-dependent Phospholipid Binding O-acyltransferase Activity Phospholipase A1 Activity Transferase Activity Hydrolase Activity Calcium-dependent Phospholipase A2 Activity Calcium-independent Phospholipase A2 Activity
	Biological Process	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair	Lipid Metabolic Process Phospholipid Metabolic Process Glycerophospholipid Metabolic Process Platelet Activating Factor Biosynthetic Process Inflammatory Response Parturition Phospholipid Catabolic Process Arachidonate Metabolic Process Intracellular Signal Transduction Phosphatidylcholine Acyl-chain Remodeling Phosphatidylethanolamine Acyl-chain Remodeling Glycerophospholipid Catabolic Process Lipid Droplet Formation
Pathways		Dissolution of Fibrin Clot	Acyl chain remodelling of PC Acyl chain remodelling of PE Acyl chain remodelling of PI Hydrolysis of LPC Hydrolysis of LPE
Drugs		Phenethyl Isothiocyanate	None
GWAS		Asthma ( 31619474 ) Diverticular disease ( 30177863 ) Serum metabolite levels ( 33031748 ) Urinary metabolite levels in chronic kidney disease ( 29545352 ) Urinary metabolite ratios in chronic kidney disease ( 29545352 )	No GWAS studies recorded
Interacting Genes		23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT	2 interacting genes: APP S100A10
Entrez ID		6281	8605
HPRD ID		00232	04673
Ensembl ID		ENSG00000197747	ENSG00000105499
Uniprot IDs		P60903	Q9UP65
PDB IDs		1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH	Not available
GO Terms Enriched among Interactors		Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding	Positive Regulation Of Proteolysis Acetylcholine Receptor Activator Activity Membrane Raft Amyloid-beta Complex PTB Domain Binding Regulation Of Cell Junction Assembly Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Response To Calcium Ion Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Endothelin Production Growth Cone Filopodium Lipoprotein Particle Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization AnxA2-p11 Complex Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Intermediate-density Lipoprotein Particle Axon Midline Choice Point Recognition Regulation Of Proteolysis Regulation Of Supramolecular Fiber Organization Positive Regulation Of Amyloid Fibril Formation Cellular Response To Norepinephrine Stimulus Growth Factor Receptor Binding Main Axon Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Plasma Membrane Repair Regulation Of Spontaneous Synaptic Transmission NMDA Selective Glutamate Receptor Signaling Pathway Regulation Of Synapse Structure Or Activity Regulation Of Toll Signaling Pathway Axon Choice Point Recognition Regulation Of Plasma Membrane Repair Heparan Sulfate Binding Signaling Receptor Activator Activity Positive Regulation Of Plasminogen Activation Peptidase Activator Activity Cellular Response To Manganese Ion Regulation Of Vesicle-mediated Transport Antifungal Humoral Response Nuclear Envelope Lumen Negative Regulation Of Blood Circulation