S100A10 and TRPV5

Number of citations: 44 (PubMedID 12660155)
Data Source: BioGRID (pull down)

		S100A10	TRPV5
Name		S100 calcium binding protein A10	transient receptor potential cation channel subfamily V member 5
Structure
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Plasma Membrane Cell Surface Nuclear Matrix Extracellular Matrix Membrane Raft Extracellular Exosome RNA Polymerase II Transcription Regulator Complex Plasma Membrane Protein Complex AnxA2-p11 Complex	Plasma Membrane Membrane Apical Plasma Membrane Calcium Channel Complex
	Molecular Function	Calcium Ion Binding Protein Binding Lipid Binding Protein Homodimerization Activity Transmembrane Transporter Binding Calcium-dependent Protein Binding	Monoatomic Ion Channel Activity Calcium Channel Activity Protein Binding Calmodulin Binding Metal Ion Binding
	Biological Process	Membrane Raft Assembly Vesicle Budding From Membrane Positive Regulation Of Plasminogen Activation MRNA Transcription By RNA Polymerase II Positive Regulation Of GTPase Activity Positive Regulation Of Exocytosis Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of Stress Fiber Assembly Positive Regulation Of Focal Adhesion Assembly Protein Localization To Plasma Membrane Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Positive Regulation Of Plasma Membrane Repair	Monoatomic Ion Transport Calcium Ion Transport Monoatomic Ion Transmembrane Transport Regulation Of Urine Volume Protein Homotetramerization Calcium Ion Homeostasis Transmembrane Transport Calcium Ion Transport Into Cytosol Calcium Ion Transmembrane Transport Calcium Ion Import Across Plasma Membrane
Pathways		Dissolution of Fibrin Clot	TRP channels
Drugs		Phenethyl Isothiocyanate	None
GWAS		Asthma ( 31619474 ) Diverticular disease ( 30177863 ) Serum metabolite levels ( 33031748 ) Urinary metabolite levels in chronic kidney disease ( 29545352 ) Urinary metabolite ratios in chronic kidney disease ( 29545352 )	Alcoholic chronic pancreatitis ( 28754779 ) Cancer ( 29299148 ) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223 )
Interacting Genes		23 interacting genes: ANXA2 ANXA7 BAD CBR3 CDK16 COPS6 CTSB DSCAM ERBB3 FSHR KCNK3 MLKL NANOS2 PLA2G4C PLG S100A3 S100Z SETDB1 SUMO2 TRPV5 TRPV6 USP2 ZGPAT	4 interacting genes: ANXA2 CALB1 EWSR1 S100A10
Entrez ID		6281	56302
HPRD ID		00232	05981
Ensembl ID		ENSG00000197747	ENSG00000127412
Uniprot IDs		P60903	Q9NQA5
PDB IDs		1A4P 1BT6 4DRW 4FTG 4HRE 4HRG 4HRH	5OEO
GO Terms Enriched among Interactors		Calcium-dependent Protein Binding Calcium-dependent Phospholipid Binding Plasma Membrane S100 Protein Binding	AnxA2-p11 Complex Positive Regulation Of Plasma Membrane Repair Regulation Of Plasma Membrane Repair Positive Regulation Of Plasminogen Activation Membrane Raft Assembly Regulation Of Plasma Membrane Organization Plasma Membrane Protein Complex Regulation Of Plasminogen Activation Positive Regulation Of Protein Processing Positive Regulation Of Protein Maturation Membrane Raft Organization Vesicle Budding From Membrane MRNA Transcription By RNA Polymerase II Membrane Assembly Regulation Of Protein Processing MRNA Transcription Regulation Of Protein Maturation Calcium-dependent Protein Binding Positive Regulation Of Exocytosis Calcium Ion Binding Metanephric Connecting Tubule Development Calcium Ion Binding Involved In Regulation Of Postsynaptic Cytosolic Calcium Ion Concentration Nuclear Matrix RNA Polymerase II Transcription Regulator Complex Positive Regulation Of Receptor-mediated Endocytosis Involved In Cholesterol Transport PCSK9-AnxA2 Complex Negative Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Calcium Ion Binding Involved In Regulation Of Presynaptic Cytosolic Calcium Ion Concentration Regulation Of Exocytosis Negative Regulation Of Receptor Catabolic Process Positive Regulation Of Intracellular Cholesterol Transport Positive Regulation Of Proteolysis Membrane Raft Positive Regulation Of Low-density Lipoprotein Particle Clearance Positive Regulation Of Intracellular Lipid Transport Metanephric Part Of Ureteric Bud Development Metanephric Distal Convoluted Tubule Development Myelin Sheath Adaxonal Region Regulation Of Low-density Lipoprotein Particle Receptor Catabolic Process Vitamin D Binding Osteoclast Development Phospholipase A2 Inhibitor Activity Transcription By RNA Polymerase II Positive Regulation Of Secretion By Cell Regulation Of Intracellular Cholesterol Transport Cuticular Plate Vesicle Organization Positive Regulation Of Secretion Regulation Of Intracellular Lipid Transport Phospholipase Inhibitor Activity