RAP2A and GABARAPL2

Number of citations of the paper that reports this interaction (PMID 12581858)
13

Data Source:
BioGRID (enzymatic study)

		RAP2A	GABARAPL2
Gene Name		RAP2A, member of RAS oncogene family	GABA(A) receptor-associated protein-like 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome	Golgi Membrane Pre-autophagosomal Structure Autophagic Vacuole Membrane Intracellular Cytoplasm Autophagic Vacuole Golgi Apparatus Cytosol Extrinsic Component Of Membrane Cytoplasmic Vesicle
	Molecular Function	GTPase Activity Protein Binding GTP Binding	SNARE Binding Protein Binding Microtubule Binding Beta-tubulin Binding GABA Receptor Binding ATPase Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane	Autophagic Vacuole Assembly Mitochondrion Degradation Intra-Golgi Vesicle-mediated Transport Autophagy Cellular Response To Nitrogen Starvation Protein Transport Positive Regulation Of ATPase Activity Nucleophagy Membrane Fusion Negative Regulation Of Proteasomal Protein Catabolic Process
Pathways
Drugs		Guanosine-5\'-Triphosphate Guanosine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ACVR1 ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 MLLT4 NEDD4 PLG RAF1 RALA RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK	50 interactors: AAMP AGTRAP AHNAK2 APP ARFGAP1 ATG13 ATG3 ATG4A ATG4B ATG4D ATG7 BCL2L13 CALCOCO1 CALCOCO2 CCDC155 CLN8 EGFR FUNDC1 GIMAP6 GOSR1 KBTBD7 KIAA1958 KLHL5 KRTAP10-7 KRTAP10-9 LRSAM1 MAP1LC3B MLX NBR1 NSF PTPRA RAP1A RAP2A RCN2 RPS2 SGTA SIK2 SQSTM1 TBC1D25 TBC1D5 TBC1D9 TBC1D9B TNIP1 TP53INP2 TSR2 UBA5 ULK1 ULK2 VDR YWHAZ
Entrez ID		5911	11345
HPRD ID		01547	16246
Ensembl ID			ENSG00000034713
Uniprot IDs		P10114	P60520
PDB IDs		1KAO 2RAP 3RAP
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Response To Stimulus Regulation Of Signaling Regulation Of Catalytic Activity Cell Communication Signal Transduction Cellular Response To Stimulus Positive Regulation Of Metabolic Process Positive Regulation Of Rap GTPase Activity Signaling Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Rap GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Rap Protein Signal Transduction Signal Transduction By Phosphorylation Regulation Of Metabolic Process Small GTPase Mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Wound Healing Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Ras Protein Signal Transduction Regulation Of Dendrite Morphogenesis Response To Wounding Regulation Of Cell Projection Organization Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Platelet Activation Regulation Of Ras GTPase Activity Cellular Response To Growth Factor Stimulus Response To Organic Substance Regulation Of Cellular Process Response To Growth Factor Regulation Of Dendrite Development Cardiovascular System Development Cell Surface Receptor Signaling Pathway Positive Regulation Of Ras GTPase Activity Regulation Of Cell Differentiation Negative Regulation Of Cell Proliferation Cell Activation Regulation Of Cellular Localization Cell Differentiation Blood Vessel Development Response To Stress Vasculature Development Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Activation Of MAPKK Activity	Autophagy Macroautophagy Response To Starvation Cellular Response To Nutrient Levels Cellular Response To Starvation Autophagic Vacuole Assembly Cellular Response To Extracellular Stimulus Response To Nutrient Levels Response To Extracellular Stimulus Vacuole Organization Mitochondrion Degradation Organelle Disassembly Nucleophagy Membrane Organization Positive Regulation Of Autophagy Response To Stress Cellular Response To Nitrogen Starvation Catabolic Process Regulation Of Autophagy Response To External Stimulus Protein Localization Establishment Of Protein Localization Protein Delipidation Mitochondrion Organization Cellular Response To Stress Positive Regulation Of Metabolic Process Organelle Assembly C-terminal Protein Lipidation Establishment Of Protein Localization To Membrane Protein Localization To Membrane Protein Transport Positive Regulation Of Cellular Metabolic Process Intracellular Transport Cellular Localization Cell Communication Positive Regulation Of Macroautophagy Cellular Component Assembly Response To Stimulus Establishment Of Localization In Cell Cellular Response To Stimulus Protein Targeting To Membrane Regulation Of Signaling Regulation Of Signal Transduction Organelle Organization Cellular Metabolic Process Protein Lipidation Lipoprotein Biosynthetic Process Negative Regulation Of Collateral Sprouting Positive Regulation Of Catalytic Activity Positive Regulation Of Hydrolase Activity
Tagcloud ?		cleave competitors degrades diaminopimelic effectors endopeptidase endopeptidases exploiting extrude heteromeric marcescens meso muropeptides neutralization neutralize orthologues pentapeptides promiscuity rap1a raps serratia ssp1 ssp2 steric tetrapenta tetrapeptides tetratetra tetratetrapeptides tripeptides
Tagcloud (Difference) ?		cleave competitors degrades diaminopimelic effectors endopeptidase endopeptidases exploiting extrude heteromeric marcescens meso muropeptides neutralization neutralize orthologues pentapeptides promiscuity rap1a raps serratia ssp1 ssp2 steric tetrapenta tetrapeptides tetratetra tetratetrapeptides tripeptides
Tagcloud (Intersection) ?