RAP2A and FKBP2

Number of citations of the paper that reports this interaction (PMID 18624398)
4

Data Source:
BioGRID (two hybrid)

		RAP2A	FKBP2
Gene Name		RAP2A, member of RAS oncogene family	FK506 binding protein 2, 13kDa
Image
Gene Ontology Annotations	Cellular Component	Cytosol Plasma Membrane Midbody Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Extracellular Vesicular Exosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding	Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding FK506 Binding
	Biological Process	Positive Regulation Of Protein Phosphorylation Microvillus Assembly Negative Regulation Of Cell Migration Actin Cytoskeleton Reorganization Positive Regulation Of Protein Autophosphorylation Rap Protein Signal Transduction Cellular Protein Localization Cellular Response To Drug Establishment Of Protein Localization Establishment Of Epithelial Cell Apical/basal Polarity Regulation Of JNK Cascade Regulation Of Dendrite Morphogenesis Protein Localization To Plasma Membrane	Protein Peptidyl-prolyl Isomerization Chaperone-mediated Protein Folding
Pathways
Drugs		Guanosine-5\'-Triphosphate Guanosine-5\'-Diphosphate
Diseases
GWAS
Protein-Protein Interactions		32 interactors: ACVR1 ARHGAP29 BMPR1B EEF1A1 ENSA FKBP2 FNTB FTL GABARAPL2 GRIN1 GRIN2D MAP4K4 MLLT4 NEDD4 PLG RAF1 RALA RALGDS RAPGEF3 RAPGEF4 RAPGEF5 RAPGEF6 RASIP1 RASSF5 RGS14 RRP9 RUNDC3A SERPINA1 SMAD1 TGFBR1 TM7SF2 TNIK	13 interactors: ARFGEF1 BAG6 BARD1 C1QC EPB41 EPB41L2 MAPK3 RAB3C RAB6A RAP2A UBQLN1 UBQLN4 VAMP2
Entrez ID		5911	2286
HPRD ID		01547	01742
Ensembl ID			ENSG00000173486
Uniprot IDs		P10114	P26885 Q53XJ5
PDB IDs		1KAO 2RAP 3RAP	2PBC
Enriched GO Terms of Interacting Partners?		Intracellular Signal Transduction Response To Stimulus Regulation Of Signaling Regulation Of Catalytic Activity Cell Communication Signal Transduction Cellular Response To Stimulus Positive Regulation Of Metabolic Process Positive Regulation Of Rap GTPase Activity Signaling Regulation Of Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Rap GTPase Activity Positive Regulation Of Catalytic Activity Regulation Of Rap Protein Signal Transduction Signal Transduction By Phosphorylation Regulation Of Metabolic Process Small GTPase Mediated Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Ras Protein Signal Transduction Regulation Of GTPase Activity Wound Healing Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Ras Protein Signal Transduction Regulation Of Dendrite Morphogenesis Response To Wounding Regulation Of Cell Projection Organization Positive Regulation Of GTPase Activity Positive Regulation Of Hydrolase Activity Platelet Activation Regulation Of Ras GTPase Activity Cellular Response To Growth Factor Stimulus Response To Organic Substance Regulation Of Cellular Process Response To Growth Factor Regulation Of Dendrite Development Cardiovascular System Development Cell Surface Receptor Signaling Pathway Positive Regulation Of Ras GTPase Activity Regulation Of Cell Differentiation Negative Regulation Of Cell Proliferation Cell Activation Regulation Of Cellular Localization Cell Differentiation Blood Vessel Development Response To Stress Vasculature Development Regulation Of Protein Metabolic Process Regulation Of Phosphorus Metabolic Process Activation Of MAPKK Activity	Ras Protein Signal Transduction Cortical Actin Cytoskeleton Organization Regulation Of Protein Metabolic Process Establishment Of Protein Localization Endomembrane System Organization Cortical Cytoskeleton Organization Small GTPase Mediated Signal Transduction Protein Localization Regulation Of Cellular Protein Metabolic Process Synaptic Vesicle Exocytosis Rab Protein Signal Transduction Cellular Protein Localization Immune System Process Negative Regulation Of Apolipoprotein Binding Positive Regulation Of Protein Glycosylation In Golgi Vesicle-mediated Transport Exocytosis Protein Localization To Membrane Cellular Localization Regulation Of Vesicle-mediated Transport Regulation Of Protein Catabolic Process Negative Regulation Of MRNA 3'-end Processing Regulation Of Intracellular Transport Neurotransmitter Secretion Synaptic Vesicle Transport Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Eosinophil Degranulation Regulation Of Cellular Localization Intracellular Signal Transduction Regulation Of Golgi Inheritance Positive Regulation Of Protein Glycosylation Secretion By Cell Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Neurotransmitter Levels Caveolin-mediated Endocytosis Positive Regulation Of Histone Phosphorylation Regulation Of Protein Binding Protein Localization To Plasma Membrane Regulation Of Exocytosis Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein Metabolic Process Tail-anchored Membrane Protein Insertion Into ER Membrane Negative Regulation Of Protein Export From Nucleus Neurotransmitter Transport Actin Cytoskeleton Organization Organelle Organization Regulation Of Golgi Organization Protein K6-linked Ubiquitination Negative Regulation Of Granulocyte Differentiation
Tagcloud ?		cleave competitors degrades diaminopimelic effectors endopeptidase endopeptidases exploiting extrude heteromeric marcescens meso muropeptides neutralization neutralize orthologues pentapeptides promiscuity rap1a raps serratia ssp1 ssp2 steric tetrapenta tetrapeptides tetratetra tetratetrapeptides tripeptides
Tagcloud (Difference) ?		cleave competitors degrades diaminopimelic effectors endopeptidase endopeptidases exploiting extrude heteromeric marcescens meso muropeptides neutralization neutralize orthologues pentapeptides promiscuity rap1a raps serratia ssp1 ssp2 steric tetrapenta tetrapeptides tetratetra tetratetrapeptides tripeptides
Tagcloud (Intersection) ?