RABIF and LAMTOR5

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RABIF	LAMTOR5
Gene Name		RAB interacting factor	late endosomal/lysosomal adaptor, MAPK and MTOR activator 5
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Gene Ontology Annotations	Cellular Component		Lysosome Cytosol Ragulator Complex
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding	Guanyl-nucleotide Exchange Factor Activity Protein Binding Protein Complex Scaffold
	Biological Process	Small GTPase Mediated Signal Transduction Protein Transport Positive Regulation Of GTPase Activity Membrane Fusion	Regulation Of Cell Size Response To Virus Viral Genome Replication Positive Regulation Of TOR Signaling Negative Regulation Of Apoptotic Process Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of GTPase Activity Protein Localization To Lysosome Cellular Response To Amino Acid Stimulus
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CCBL2 ITGA2 ITGA3 ITGA5 ITGA6 LAMTOR5 RAB15 RAB1A RAB3A RAB8A RASSF5 REL TCF4 TERF2IP UTP14A	16 interactors: CEP70 EEF1A1 GAPDH GIT1 GPRASP1 KIAA1377 LAMTOR4 LRIF1 MAF1 MEOX2 NCOA6 RABIF TAF9 UTP14A YTHDC1 ZBTB16
Entrez ID		5877	10542
HPRD ID		04566	09773
Ensembl ID			ENSG00000134248
Uniprot IDs		P47224 Q53EV1	O43504
PDB IDs		1FWQ 2FU5	3MS6 3MSH
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Cell Adhesion Mediated By Integrin Cell-substrate Adhesion Integrin-mediated Signaling Pathway Protein Secretion Regulation Of Signaling Cellular Response To Stimulus Positive Regulation Of Metabolic Process Protein Localization Vesicle Docking Involved In Exocytosis Vesicle Localization Cellular Protein Localization Ras Protein Signal Transduction Skin Development Vesicle Docking Regulation Of Cellular Localization Membrane Docking Signal Transduction Anatomical Structure Morphogenesis Cell Projection Organization Positive Regulation Of Glycoprotein Metabolic Process Response To Stimulus Positive Regulation Of Cell-substrate Adhesion Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Metabolic Process Signaling Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Cell Adhesion Regulation Of Vesicle-mediated Transport Formation Of Primary Germ Layer Positive Regulation Of Regulated Secretory Pathway Cell Communication Organelle Localization Cellular Component Maintenance Regulation Of Exocytosis Blood Coagulation Cell Migration Hemostasis Cell-matrix Adhesion Response To Extracellular Stimulus Mesodermal Cell Differentiation Establishment Of Protein Localization Cell Motility Intracellular Protein Transport Regulation Of Protein Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Gastrulation Generation Of Neurons	RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Transcription Factor TFIIIB Complex Assembly Peptidyl-cysteine S-trans-nitrosylation Gene Expression Neuron Death Nucleobase-containing Compound Metabolic Process G-protein Coupled Receptor Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Embryonic Pattern Specification Protein Stabilization Negative Regulation Of Transcription From RNA Polymerase III Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Peptidyl-cysteine S-nitrosylation Positive Regulation Of NK T Cell Differentiation Regulation Of Protein Stability Male Germ-line Stem Cell Asymmetric Division Somite Specification Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Glucocorticoid Receptor Signaling Pathway Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Macromolecule Biosynthetic Process
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