RABIF and LMCD1

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		RABIF	LMCD1
Name		RAB interacting factor	LIM and cysteine rich domains 1
Structure			No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Nucleus Nucleoplasm Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Small GTPase-mediated Signal Transduction Protein Transport Membrane Fusion	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cardiac Muscle Hypertrophy Positive Regulation Of Calcineurin-NFAT Signaling Cascade
Pathways		None	Surfactant metabolism
GWAS		No GWAS studies recorded	Brain volume in infants (intracranial brain volume) ( 28763065 ) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223 ) Itch intensity from mosquito bite adjusted by bite size ( 28199695 ) Low high density lipoprotein cholesterol levels ( 26879886 ) Metabolite levels ( 23823483 ) Mitral valve prolapse ( 26301497 ) Platelet count ( 32888494 ) Plateletcrit ( 32888494 ) Rumination (response to stress) ( 30886212 ) Uterine fibroid number (single vs multiple) ( 30196971 )
Interacting Genes		27 interacting genes: EIF3F ITGA2 ITGA3 ITGA5 ITGA6 KIFC3 KYAT3 LAMTOR5 LARP1B LMCD1 LNX1 LRMDA LZTS1 RAB10 RAB15 RAB19 RAB1B RAB3A RAB3C RAB3D RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544	9 interacting genes: APP FBXO25 IKBKG NKX3-1 PRKAG3 RABIF TEKT4 TRIM55 TRIM63
Entrez ID		5877	29995
HPRD ID		04566	06891
Ensembl ID		ENSG00000183155	ENSG00000071282
Uniprot IDs		P47224 Q53EV1	B4DEY6 B7Z6R5 H7C3D2 Q9NZU5
PDB IDs		1FWQ 2FU5	Not available
GO Terms Enriched among Interactors		Myosin V Binding GTPase Activity GTP Binding Integrin Complex Exocytosis GTP-dependent Protein Binding Integrin-mediated Signaling Pathway Cell-matrix Adhesion Cell-substrate Junction Assembly Secretion By Cell Cell-substrate Junction Organization Cell Junction Organization Synaptic Vesicle Positive Regulation Of Regulated Secretory Pathway Perinuclear Region Of Cytoplasm Secretory Vesicle Cell-cell Adhesion Cell-substrate Adhesion Secretion Skin Morphogenesis Cellular Component Maintenance Protein Transport G Protein Activity Intracellular Protein Localization Regulation Of Exocytosis Mesodermal Cell Differentiation Positive Regulation Of Exocytosis Laminin Binding Focal Adhesion Hydrolase Activity Establishment Of Protein Localization Signaling Receptor Activity Golgi Organization Cell Adhesion Mediated By Integrin Nucleotide Binding Response To Muscle Activity Regulation Of Regulated Secretory Pathway Metal Ion Binding Integrin Alpha6-beta4 Complex Regulation Of Vesicle-mediated Transport Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Viral Process Integrin Binding Vesicle-mediated Transport Axonogenesis Cell Adhesion Integrin Alpha6-beta1 Complex Positive Regulation Of Epithelial Cell Migration Integrin Alpha3-beta1 Complex	Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Response To Interleukin-1 Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Regulation Of Generation Of Precursor Metabolites And Energy Intracellular Signal Transduction Regulation Of Intrinsic Apoptotic Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Innate Immune Response Amyloid-beta Complex Growth Cone Lamellipodium Defense Response To Symbiont Regulation Of Response To Calcium Ion Defense Response To Other Organism Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Non-canonical NF-kappaB Signal Transduction Positive Regulation Of Androgen Secretion MADS Box Domain Binding Canonical NF-kappaB Signal Transduction Regulation Of Small Molecule Metabolic Process Intracellular Signaling Cassette Acetylcholine Receptor Activator Activity Regulation Of Response To Endoplasmic Reticulum Stress Lipoprotein Particle Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Protein Import Dorsal Aorta Development Response To Electrical Stimulus Involved In Regulation Of Muscle Adaptation PTB Domain Binding Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Regulation Of Non-canonical NF-kappaB Signal Transduction Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Endothelin Production Growth Cone Filopodium Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Signal Transduction Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Ubiquitin Ligase Complex Linear Polyubiquitin Binding Response To Muscle Activity Involved In Regulation Of Muscle Adaptation Regulation Of Carbon Utilization Response To Other Organism Positive Regulation Of Mitotic Cell Cycle Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Response To Stress