RABIF and RAB3C

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		RABIF	RAB3C
Description		RAB interacting factor	RAB3C, member RAS oncogene family
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GO Annotations	Cellular Component	Cytosol Membrane	Endosome Plasma Membrane Synaptic Vesicle Membrane Vesicle Perinuclear Region Of Cytoplasm
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Small GTPase-mediated Signal Transduction Protein Transport Membrane Fusion	Exocytosis Protein Transport Regulation Of Exocytosis Antigen Processing And Presentation
Pathways			RAB geranylgeranylation
Drugs
Diseases
GWAS			Breast cancer ( 23535729 29059683) Gut microbiota (bacterial taxa, hurdle binary method) ( 32572223) Hippocampal volume ( 25625606) Metabolite levels ( 23823483) Perceived intensity of sweet substances ( 31005972) Sleep duration (long sleep) ( 30846698)
Interacting Genes		27 interacting genes: EIF3F ITGA2 ITGA3 ITGA5 ITGA6 KIFC3 KYAT3 LAMTOR5 LARP1B LMCD1 LNX1 LRMDA LZTS1 RAB10 RAB15 RAB19 RAB1B RAB3A RAB3C RAB3D RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544	7 interacting genes: CRYAA FKBP2 RABIF REP15 RIMS2 RPH3AL VRTN
Entrez ID		5877	115827
HPRD ID		04566	06704
Ensembl ID		ENSG00000183155	ENSG00000152932
Uniprot IDs		P47224 Q53EV1	Q96E17
PDB IDs		1FWQ 2FU5	6Y7G
Enriched GO Terms of Interacting Partners?		Myosin V Binding GTPase Activity GTP Binding Integrin Complex Exocytosis GTP-dependent Protein Binding Integrin-mediated Signaling Pathway Cell-matrix Adhesion Cell-substrate Junction Assembly Secretion By Cell Cell-substrate Junction Organization Cell Junction Organization Synaptic Vesicle Positive Regulation Of Regulated Secretory Pathway Perinuclear Region Of Cytoplasm Secretory Vesicle Cell-cell Adhesion Cell-substrate Adhesion Secretion Skin Morphogenesis Cellular Component Maintenance Protein Transport G Protein Activity Intracellular Protein Localization Regulation Of Exocytosis Mesodermal Cell Differentiation Positive Regulation Of Exocytosis Laminin Binding Focal Adhesion Hydrolase Activity Establishment Of Protein Localization Signaling Receptor Activity Golgi Organization Cell Adhesion Mediated By Integrin Nucleotide Binding Response To Muscle Activity Regulation Of Regulated Secretory Pathway Metal Ion Binding Integrin Alpha6-beta4 Complex Regulation Of Vesicle-mediated Transport Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Viral Process Integrin Binding Vesicle-mediated Transport Axonogenesis Cell Adhesion Integrin Alpha6-beta1 Complex Positive Regulation Of Epithelial Cell Migration Integrin Alpha3-beta1 Complex
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