RABIF and ITGA3

Number of citations of the paper that reports this interaction (PMID 10094488)
9

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		RABIF	ITGA3
Gene Name		RAB interacting factor	integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component		Plasma Membrane Focal Adhesion Integrin Complex External Side Of Plasma Membrane Cell Surface Basolateral Plasma Membrane Growth Cone Filopodium Membrane Integrin Alpha3-beta1 Complex Receptor Complex Perinuclear Region Of Cytoplasm Excitatory Synapse Extracellular Vesicular Exosome Invadopodium Membrane Cell Periphery Synaptic Membrane
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding	Glycoprotein Binding Fibronectin Binding Protease Binding Integrin Binding Protein Binding Collagen Binding Protein Domain Specific Binding Laminin Binding Metal Ion Binding Protein Heterodimerization Activity
	Biological Process	Small GTPase Mediated Signal Transduction Protein Transport Positive Regulation Of GTPase Activity Membrane Fusion	Neuron Migration Cell-matrix Adhesion Integrin-mediated Signaling Pathway Heart Development Blood Coagulation Memory Positive Regulation Of Gene Expression Positive Regulation Of Epithelial Cell Migration Positive Regulation Of Cell-substrate Adhesion Positive Regulation Of Neuron Projection Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Wnt Signaling Pathway Extracellular Matrix Organization Lung Development Regulation Of BMP Signaling Pathway Negative Regulation Of Cell Projection Organization Response To Gonadotropin Negative Regulation Of Rho Protein Signal Transduction Exploration Behavior Response To Drug Skin Development Mesodermal Cell Differentiation Leukocyte Migration Maternal Process Involved In Female Pregnancy Nephron Development Positive Regulation Of Establishment Of Protein Localization To Plasma Membrane Dendritic Spine Maintenance Renal Filtration
Pathways			Laminin interactions Integrin cell surface interactions Basigin interactions Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS
Protein-Protein Interactions		15 interactors: CCBL2 ITGA2 ITGA3 ITGA5 ITGA6 LAMTOR5 RAB15 RAB1A RAB3A RAB8A RASSF5 REL TCF4 TERF2IP UTP14A	15 interactors: ADAM9 BIN1 CALR CD151 CD82 CD9 FHL2 FN1 HPS5 HSPD1 ITGB1 LGALS8 RABIF TIMP2 TSPAN4
Entrez ID		5877	3675
HPRD ID		04566	05431
Ensembl ID			ENSG00000005884
Uniprot IDs		P47224 Q53EV1	P26006
PDB IDs		1FWQ 2FU5
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Cell Adhesion Mediated By Integrin Cell-substrate Adhesion Integrin-mediated Signaling Pathway Protein Secretion Regulation Of Signaling Cellular Response To Stimulus Positive Regulation Of Metabolic Process Protein Localization Vesicle Docking Involved In Exocytosis Vesicle Localization Cellular Protein Localization Ras Protein Signal Transduction Skin Development Vesicle Docking Regulation Of Cellular Localization Membrane Docking Signal Transduction Anatomical Structure Morphogenesis Cell Projection Organization Positive Regulation Of Glycoprotein Metabolic Process Response To Stimulus Positive Regulation Of Cell-substrate Adhesion Cell Morphogenesis Involved In Differentiation Positive Regulation Of Protein Metabolic Process Signaling Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of Cell Adhesion Regulation Of Vesicle-mediated Transport Formation Of Primary Germ Layer Positive Regulation Of Regulated Secretory Pathway Cell Communication Organelle Localization Cellular Component Maintenance Regulation Of Exocytosis Blood Coagulation Cell Migration Hemostasis Cell-matrix Adhesion Response To Extracellular Stimulus Mesodermal Cell Differentiation Establishment Of Protein Localization Cell Motility Intracellular Protein Transport Regulation Of Protein Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus Viral Life Cycle Gastrulation Generation Of Neurons	Cell Activation Positive Regulation Of Cell Adhesion Extracellular Matrix Organization Extracellular Structure Organization Calcium-independent Cell-matrix Adhesion Cellular Component Assembly Cell Junction Assembly Leukocyte Activation Positive Regulation Of Cell Development Cell-cell Adhesion Mediated By Integrin Regulation Of Neuron Differentiation Positive Regulation Of Catalytic Activity System Development Regulation Of Cell Adhesion Extracellular Matrix Disassembly Cell Differentiation Positive Regulation Of Endocytosis Positive Regulation Of Metabolic Process Cell Adhesion Mediated By Integrin Muscle Cell Differentiation Cardiac Muscle Cell Differentiation Cell Adhesion Regulation Of Neurogenesis Multicellular Organismal Development Cardiocyte Differentiation Anatomical Structure Development Lymphocyte Activation Positive Regulation Of Neurogenesis Blood Coagulation Regulation Of Cell Development Positive Regulation Of Cell Differentiation Hemostasis Immune System Process B Cell Activation Cell-matrix Adhesion Response To Hormone Regulation Of Endocytosis Cardiac Muscle Tissue Development Muscle Structure Development Developmental Process Regulation Of Catalytic Activity Single Organismal Cell-cell Adhesion Neurogenesis Cell-substrate Adhesion Positive Regulation Of Hydrolase Activity Protein Maturation Striated Muscle Cell Differentiation Regulation Of Body Fluid Levels Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process
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