RABIF and RAB19

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		RABIF	RAB19
Name		RAB interacting factor	RAB19, member RAS oncogene family
Structure			No pdb structure
GO Annotations	Cellular Component	Cytosol Membrane	Plasma Membrane Endomembrane System Membrane Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Metal Ion Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Small GTPase-mediated Signal Transduction Protein Transport Membrane Fusion	Autophagosome Assembly Intracellular Protein Transport
Pathways		None	RAB geranylgeranylation
GWAS		No GWAS studies recorded	Adverse response to drug ( 30420678 )
Interacting Genes		27 interacting genes: EIF3F ITGA2 ITGA3 ITGA5 ITGA6 KIFC3 KYAT3 LAMTOR5 LARP1B LMCD1 LNX1 LRMDA LZTS1 RAB10 RAB15 RAB19 RAB1B RAB3A RAB3C RAB3D RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544	4 interacting genes: KRTAP10-8 LSM11 RABIF VCAN
Entrez ID		5877	401409
HPRD ID		04566	17946
Ensembl ID		ENSG00000183155	ENSG00000146955
Uniprot IDs		P47224 Q53EV1	A4D1S5
PDB IDs		1FWQ 2FU5	Not available
GO Terms Enriched among Interactors		Myosin V Binding GTPase Activity GTP Binding Integrin Complex Exocytosis GTP-dependent Protein Binding Integrin-mediated Signaling Pathway Cell-matrix Adhesion Cell-substrate Junction Assembly Secretion By Cell Cell-substrate Junction Organization Cell Junction Organization Synaptic Vesicle Positive Regulation Of Regulated Secretory Pathway Perinuclear Region Of Cytoplasm Secretory Vesicle Cell-cell Adhesion Cell-substrate Adhesion Secretion Skin Morphogenesis Cellular Component Maintenance Protein Transport G Protein Activity Intracellular Protein Localization Regulation Of Exocytosis Mesodermal Cell Differentiation Positive Regulation Of Exocytosis Laminin Binding Focal Adhesion Hydrolase Activity Establishment Of Protein Localization Signaling Receptor Activity Golgi Organization Cell Adhesion Mediated By Integrin Nucleotide Binding Response To Muscle Activity Regulation Of Regulated Secretory Pathway Metal Ion Binding Integrin Alpha6-beta4 Complex Regulation Of Vesicle-mediated Transport Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Viral Process Integrin Binding Vesicle-mediated Transport Axonogenesis Cell Adhesion Integrin Alpha6-beta1 Complex Positive Regulation Of Epithelial Cell Migration Integrin Alpha3-beta1 Complex	Interphotoreceptor Matrix Protein Tyrosine Phosphatase Activator Activity U7 SnRNP U7 SnRNA Binding MRNA 3'-end Processing By Stem-loop Binding And Cleavage Histone Pre-mRNA 3'end Processing Complex Perineuronal Net Extracellular Matrix Structural Constituent Conferring Compression Resistance Hyaluronic Acid Binding Glycosaminoglycan Binding Regulation Of Chromatin Organization Telomerase Holoenzyme Complex Histone MRNA Metabolic Process Glial Cell Migration