RABIF and RASSF5

Number of citations: 56 (PubMedID 25416956)
Data Source: BioGRID (two hybrid, two hybrid)

		RABIF	RASSF5
Name		RAB interacting factor	Ras association domain family member 5
Structure
GO Annotations	Cellular Component	Cytosol Membrane	Nucleus Cytoplasm Cytoskeleton Microtubule
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding
	Biological Process	Post-Golgi Vesicle-mediated Transport Small GTPase-mediated Signal Transduction Protein Transport Membrane Fusion	Apoptotic Process Signal Transduction Positive Regulation Of Protein Ubiquitination Lymphocyte Proliferation Negative Regulation Of Lymphocyte Proliferation Regulation Of Protein Localization To Nucleus
GWAS		No GWAS studies recorded	Inflammatory bowel disease ( 23128233 ) Late-onset Alzheimer's disease ( 27770636 ) Neurofibrillary tangles ( 25188341 )
Interacting Genes		27 interacting genes: EIF3F ITGA2 ITGA3 ITGA5 ITGA6 KIFC3 KYAT3 LAMTOR5 LARP1B LMCD1 LNX1 LRMDA LZTS1 RAB10 RAB15 RAB19 RAB1B RAB3A RAB3C RAB3D RAB8A RASSF5 REL TCF4 TERF2IP UTP14A ZNF544	30 interacting genes: ADH6 AMOTL2 APPBP2 BTRC HRAS KRAS KRT40 KRTAP4-2 LSM7 MRAS MYLIP NRAS RABIF RALA RAP1B RAP2A RAP2B RASSF1 RASSF2 REL RRAS RRAS2 SMAD4 STK4 TERF2IP TRAF1 TRAF2 UBQLN1 UBQLN2 VPS28
Entrez ID		5877	83593
HPRD ID		04566	06117
Ensembl ID		ENSG00000183155	ENSG00000266094
Uniprot IDs		P47224 Q53EV1	A8K5F3 Q8WWW0
PDB IDs		1FWQ 2FU5	4LGD 4OH8
GO Terms Enriched among Interactors		Myosin V Binding GTPase Activity GTP Binding Integrin Complex Exocytosis GTP-dependent Protein Binding Integrin-mediated Signaling Pathway Cell-matrix Adhesion Cell-substrate Junction Assembly Secretion By Cell Cell-substrate Junction Organization Cell Junction Organization Synaptic Vesicle Positive Regulation Of Regulated Secretory Pathway Perinuclear Region Of Cytoplasm Secretory Vesicle Cell-cell Adhesion Cell-substrate Adhesion Secretion Skin Morphogenesis Cellular Component Maintenance Protein Transport G Protein Activity Intracellular Protein Localization Regulation Of Exocytosis Mesodermal Cell Differentiation Positive Regulation Of Exocytosis Laminin Binding Focal Adhesion Hydrolase Activity Establishment Of Protein Localization Signaling Receptor Activity Golgi Organization Cell Adhesion Mediated By Integrin Nucleotide Binding Response To Muscle Activity Regulation Of Regulated Secretory Pathway Metal Ion Binding Integrin Alpha6-beta4 Complex Regulation Of Vesicle-mediated Transport Regulation Of Presynaptic Dense Core Granule Exocytosis Evoked Neurotransmitter Secretion Viral Process Integrin Binding Vesicle-mediated Transport Axonogenesis Cell Adhesion Integrin Alpha6-beta1 Complex Positive Regulation Of Epithelial Cell Migration Integrin Alpha3-beta1 Complex	GDP Binding Intracellular Signaling Cassette Small GTPase-mediated Signal Transduction Intracellular Signal Transduction G Protein Activity Ras Protein Signal Transduction GTPase Activity GTP Binding Signal Transduction Cytosol Rap Protein Signal Transduction Regulation Of Intracellular Signal Transduction Protein-containing Complex Binding Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Schwann Cell Migration Regulation Of Signal Transduction Regulation Of Protein Modification Process Regulation Of MAPK Cascade Non-canonical NF-kappaB Signal Transduction Regulation Of Protein Catabolic Process Positive Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Branching Morphogenesis Of An Epithelial Tube Nucleotide Binding Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of JNK Cascade Thioesterase Binding Morphogenesis Of A Branching Epithelium Morphogenesis Of A Branching Structure Regulation Of Canonical NF-kappaB Signal Transduction Cytoplasmic Vesicle Membrane Morphogenesis Of An Epithelium Hydrolase Activity Macromolecule Catabolic Process Positive Regulation Of Macromolecule Metabolic Process Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity Modification-dependent Protein Catabolic Process Regulation Of Protein Stability Positive Regulation Of Protein Modification Process Positive Regulation Of ERAD Pathway Positive Regulation Of Protein Catabolic Process Bounding Membrane Of Organelle Regulation Of Protein Phosphorylation Regulation Of Glial Cell Migration Autophagosome Assembly