Wiki-Pi
Answer Survey
Home
About
Help
Advanced Search
MAP4K2 and MAP3K11
Number of citations of the paper that reports this interaction (PMID
11784851
)
24
Data Source:
HPRD
(in vitro)
MAP4K2
MAP3K11
Gene Name
mitogen-activated protein kinase kinase kinase kinase 2
mitogen-activated protein kinase kinase kinase 11
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Golgi Membrane
Cytoplasm
Basolateral Plasma Membrane
Cytoplasm
Centrosome
Microtubule
Membrane
Molecular Function
Protein Serine/threonine Kinase Activity
Receptor Signaling Protein Serine/threonine Kinase Activity
Small GTPase Regulator Activity
Protein Binding
ATP Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Protein Kinase Activity
Protein Serine/threonine Kinase Activity
JUN Kinase Kinase Kinase Activity
Protein Tyrosine Kinase Activity
Protein Binding
ATP Binding
Mitogen-activated Protein Kinase Kinase Binding
Mitogen-activated Protein Kinase Kinase Kinase Binding
Identical Protein Binding
Protein Homodimerization Activity
Rac GTPase Binding
Biological Process
Protein Phosphorylation
Vesicle Targeting
Immune Response
JNK Cascade
Activation Of JUN Kinase Activity
Intracellular Signal Transduction
Innate Immune Response
Positive Regulation Of JNK Cascade
Activation Of MAPK Activity
Protein Phosphorylation
Microtubule-based Process
JNK Cascade
Activation Of JNKK Activity
Activation Of JUN Kinase Activity
Cell Death
Cell Proliferation
Peptidyl-tyrosine Phosphorylation
Positive Regulation Of JUN Kinase Activity
Positive Regulation Of Neuron Apoptotic Process
Positive Regulation Of JNK Cascade
Protein Autophosphorylation
Pathways
Drugs
Diseases
GWAS
Urate levels (
21768215
)
Protein-Protein Interactions
13 interactors:
DEFB1
HNRNPA2B1
MAP2K4
MAP3K11
MCM3AP-AS1
NACAD
POT1
PRDX4
RAB8A
SERPINA4
SNRNP35
TRAF2
XRCC6
27 interactors:
AKT1
APP
CDC42
CHUK
CLEC4G
COPS5
EPS8
IKBKB
KIF17
KIF3A
KIF3B
KIFAP3
MAP2K4
MAP2K7
MAP3K12
MAP4K1
MAP4K2
MAPK8IP1
MAPK8IP2
MAPK8IP3
PIN1
RAC1
RHOG
SH3RF1
STUB1
TRAF6
UBC
Entrez ID
5871
4296
HPRD ID
04408
02502
Ensembl ID
ENSG00000168067
ENSG00000173327
Uniprot IDs
Q12851
Q86VU3
Q16584
PDB IDs
Enriched GO Terms of Interacting Partners
?
Positive Regulation Of JUN Kinase Activity
Regulation Of JUN Kinase Activity
Positive Regulation Of JNK Cascade
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of JNK Cascade
Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Transferase Activity
Positive Regulation Of MAP Kinase Activity
Activation Of JUN Kinase Activity
Activation Of Protein Kinase Activity
Positive Regulation Of Protein Serine/threonine Kinase Activity
Regulation Of Neuron Death
Regulation Of MAP Kinase Activity
I-kappaB Kinase/NF-kappaB Signaling
Positive Regulation Of Neuron Apoptotic Process
TRIF-dependent Toll-like Receptor Signaling Pathway
MyD88-independent Toll-like Receptor Signaling Pathway
Innate Immune Response
Toll-like Receptor 3 Signaling Pathway
Positive Regulation Of DNA Replication
Telomere Maintenance
Positive Regulation Of DNA Strand Elongation
Negative Regulation Of Male Germ Cell Proliferation
Positive Regulation Of Neuron Death
DNA Duplex Unwinding
DNA Geometric Change
Toll-like Receptor 4 Signaling Pathway
JNK Cascade
Positive Regulation Of MAPK Cascade
Toll-like Receptor Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Cellular Hyperosmotic Salinity Response
Regulation Of Male Germ Cell Proliferation
Golgi Vesicle Fusion To Target Membrane
Telomere Formation Via Telomerase
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Kinase Activity
Regulation Of DNA Replication
Cellular Response To Sorbitol
Pattern Recognition Receptor Signaling Pathway
Innate Immune Response-activating Signal Transduction
Activation Of MAPK Activity
Activation Of Innate Immune Response
Positive Regulation Of DNA Metabolic Process
Positive Regulation Of Apoptotic Process
Positive Regulation Of Programmed Cell Death
Cellular Response To X-ray
Regulation Of JNK Cascade
Regulation Of Stress-activated MAPK Cascade
JNK Cascade
Regulation Of MAPK Cascade
Regulation Of Signal Transduction
Stress-activated MAPK Cascade
Stress-activated Protein Kinase Signaling Cascade
Positive Regulation Of Transferase Activity
Regulation Of Intracellular Signal Transduction
Regulation Of Signaling
Regulation Of Phosphorylation
Response To Stress
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Signal Transduction
Regulation Of Kinase Activity
MAPK Cascade
Regulation Of Protein Phosphorylation
Positive Regulation Of Kinase Activity
Positive Regulation Of Cellular Protein Metabolic Process
Positive Regulation Of Protein Modification Process
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Kinase Activity
Signal Transduction By Phosphorylation
Positive Regulation Of Protein Metabolic Process
Intracellular Signal Transduction
Positive Regulation Of Catalytic Activity
Positive Regulation Of Intracellular Signal Transduction
Regulation Of Cellular Protein Metabolic Process
Regulation Of Catalytic Activity
Positive Regulation Of Phosphorylation
Positive Regulation Of Stress-activated MAPK Cascade
Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade
Regulation Of Protein Metabolic Process
Regulation Of JUN Kinase Activity
Fc Receptor Signaling Pathway
Innate Immune Response
Positive Regulation Of MAPK Cascade
Signal Transduction
Toll-like Receptor 5 Signaling Pathway
Positive Regulation Of Metabolic Process
Toll-like Receptor 10 Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Toll-like Receptor TLR6:TLR2 Signaling Pathway
Toll-like Receptor TLR1:TLR2 Signaling Pathway
Immune System Process
Toll-like Receptor 2 Signaling Pathway
Positive Regulation Of JNK Cascade
Toll-like Receptor 9 Signaling Pathway
TRIF-dependent Toll-like Receptor Signaling Pathway
Tagcloud
?
acceleration
activate
agar
besides
carcinogenesis
cdk2
colony
crkl
cycle
cycling1
facilitate
g1
htert
mb
mda
methylate
methyltransferase
mynd
oncogenes
phenotypes
pik3cb
riz
set
smyd3
soft
stat1
transduction
transformed
wnt10b
Tagcloud (Difference)
?
acceleration
activate
agar
besides
carcinogenesis
cdk2
colony
crkl
cycle
cycling1
facilitate
g1
htert
mb
mda
methylate
methyltransferase
mynd
oncogenes
phenotypes
pik3cb
riz
set
smyd3
soft
stat1
transduction
transformed
wnt10b
Tagcloud (Intersection)
?