VPS52 and VPS53

Number of citations of the paper that reports this interaction (PMID 15878329)
24

Data Source:
HPRD (in vitro, in vivo)

		VPS52	VPS53
Gene Name		vacuolar protein sorting 52 homolog (S. cerevisiae)	vacuolar protein sorting 53 homolog (S. cerevisiae)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm	GARP Complex Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Ectodermal Cell Differentiation Protein Transport Embryonic Ectodermal Digestive Tract Development	Protein Transport Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS			Prostate cancer ( 23535732)
Protein-Protein Interactions		49 interactors: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 KANK2 KIAA1217 KIF5B KLC3 LMO4 MAPK3 METTL13 MFAP1 MRPL11 NFKBIB NOP2 PPP1R18 PRKAA1 PRKAA2 RAB4A RNF41 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS51 VPS53 VPS54 WTAP ZMAT2	4 interactors: EXOC2 VPS51 VPS52 VPS54
Entrez ID		6293	55275
HPRD ID		09142	07720
Ensembl ID		ENSG00000223501	ENSG00000141252
Uniprot IDs		B4DNI9 Q8N1B4	B3KS06 Q5VIR6
PDB IDs
Enriched GO Terms of Interacting Partners?		Anion Homeostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Establishment Of Localization In Cell Insulin Receptor Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Energy Homeostasis TRIF-dependent Toll-like Receptor Signaling Pathway Autophagy Cellular Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Glycolytic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Transport MyD88-dependent Toll-like Receptor Signaling Pathway Fatty Acid Homeostasis Regulation Of Generation Of Precursor Metabolites And Energy Toll-like Receptor 4 Signaling Pathway Interleukin-1-mediated Signaling Pathway Endosomal Transport Cellular Response To Insulin Stimulus Gene Expression Regulation Of Circadian Rhythm Histone-serine Phosphorylation Cellular Response To Glucose Starvation Toll-like Receptor Signaling Pathway RNA Metabolic Process Regulation Of Glycolytic Process Response To Peptide Hormone Response To Hormone Negative Regulation Of TOR Signaling Response To Peptide Cholesterol Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cerebellar Molecular Layer Development Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of Autophagy Activation Of MAPK Activity Activation Of Innate Immune Response Organelle Disassembly Cellular Response To Peptide Hormone Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Post-Golgi Vesicle-mediated Transport Golgi Vesicle Transport Golgi To Plasma Membrane Transport Protein Transport Establishment Of Protein Localization Protein Localization Retrograde Transport, Endosome To Golgi Cytoplasmic Transport Embryonic Ectodermal Digestive Tract Development Endosomal Transport Vesicle-mediated Transport Ectodermal Cell Differentiation Intracellular Transport Golgi To Vacuole Transport Transport Establishment Of Localization In Cell Neurofilament Cytoskeleton Organization Cellular Localization Ectoderm Development Homeostasis Of Number Of Cells Within A Tissue Intermediate Filament Cytoskeleton Organization Embryonic Digestive Tract Development Intermediate Filament-based Process Musculoskeletal Movement Vacuolar Transport Digestive Tract Development Digestive System Development
Tagcloud ?		biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler	biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps52 vps54 wobbler
Tagcloud (Difference) ?
Tagcloud (Intersection) ?		biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps52 vps53 vps54 wobbler