VPS52 and LMO4

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		VPS52	LMO4
Gene Name		vacuolar protein sorting 52 homolog (S. cerevisiae)	LIM domain only 4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Apparatus Endosome Membrane Perinuclear Region Of Cytoplasm	Transcription Factor Complex
	Molecular Function	Protein Binding Syntaxin Binding	Enhancer Sequence-specific DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Zinc Ion Binding
	Biological Process	Ectodermal Cell Differentiation Protein Transport Embryonic Ectodermal Digestive Tract Development	Neural Tube Closure Ventricular Septum Development Transcription From RNA Polymerase II Promoter Ventral Spinal Cord Interneuron Differentiation Spinal Cord Motor Neuron Differentiation Spinal Cord Association Neuron Differentiation Negative Regulation Of Protein Complex Assembly Regulation Of Cell Fate Specification Positive Regulation Of Transcription From RNA Polymerase II Promoter Thymus Development Regulation Of Cell Activation
Pathways
Drugs
Diseases
GWAS			Response to TNF antagonist treatment ( 18615156) White blood cell types ( 21738478)
Protein-Protein Interactions		49 interactors: AAMP ARNT2 ATP6V1D C1orf109 CACNA1A CCDC146 CCDC33 DDX6 EPM2AIP1 FAM184A GFM2 GOLGA1 HAUS1 HEATR1 KANK2 KIAA1217 KIF5B KLC3 LMO4 MAPK3 METTL13 MFAP1 MRPL11 NFKBIB NOP2 PPP1R18 PRKAA1 PRKAA2 RAB4A RNF41 SH2D4A STX11 TBC1D22B TCEANC TEAD4 THAP11 TPM3 TRAF6 TSSK3 TSTD2 TXLNA TXN2 USP2 VPS28 VPS51 VPS53 VPS54 WTAP ZMAT2	53 interactors: AES AMOT AMOTL2 BANP BRCA1 CALCOCO2 CCDC102B CEP170P1 CSNK2B DDB1 DEAF1 ERCC6L GABPB1 GADD45A GOLGA2 GRHL2 GSK3B ITSN1 KANK2 KIAA1958 KIF3B KPNA1 KRT15 KRT31 KRT40 LDB1 LDB2 MERTK MTA1 NFYC NHLH1 NONO PDE4DIP PITPNB PLK1 PPARG RBBP8 RBPMS RPS6KA6 SEC24D SMAD4 SMAD9 TCF21 TCF4 TFIP11 TINAGL1 TNFSF11 TP53BP2 TSEN15 VPS52 ZBTB43 ZNF397 ZNF675
Entrez ID		6293	8543
HPRD ID		09142	09122
Ensembl ID		ENSG00000223501	ENSG00000143013
Uniprot IDs		B4DNI9 Q8N1B4	P61968
PDB IDs			2L4Z
Enriched GO Terms of Interacting Partners?		Anion Homeostasis Toll-like Receptor 5 Signaling Pathway Toll-like Receptor 10 Signaling Pathway Establishment Of Localization In Cell Insulin Receptor Signaling Pathway Toll-like Receptor TLR6:TLR2 Signaling Pathway Toll-like Receptor TLR1:TLR2 Signaling Pathway Response To Insulin Toll-like Receptor 2 Signaling Pathway Toll-like Receptor 9 Signaling Pathway Regulation Of Energy Homeostasis TRIF-dependent Toll-like Receptor Signaling Pathway Autophagy Cellular Localization Retrograde Transport, Endosome To Golgi Positive Regulation Of Glycolytic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Intracellular Transport MyD88-dependent Toll-like Receptor Signaling Pathway Fatty Acid Homeostasis Regulation Of Generation Of Precursor Metabolites And Energy Toll-like Receptor 4 Signaling Pathway Interleukin-1-mediated Signaling Pathway Endosomal Transport Cellular Response To Insulin Stimulus Gene Expression Regulation Of Circadian Rhythm Histone-serine Phosphorylation Cellular Response To Glucose Starvation Toll-like Receptor Signaling Pathway RNA Metabolic Process Regulation Of Glycolytic Process Response To Peptide Hormone Response To Hormone Negative Regulation Of TOR Signaling Response To Peptide Cholesterol Biosynthetic Process Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Cerebellar Molecular Layer Development Negative Regulation Of Apolipoprotein Binding Negative Regulation Of Glucosylceramide Biosynthetic Process Cold Acclimation Positive Regulation Of Autophagy Activation Of MAPK Activity Activation Of Innate Immune Response Organelle Disassembly Cellular Response To Peptide Hormone Stimulus Regulation Of Sequence-specific DNA Binding Transcription Factor Activity	Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Tissue Development Negative Regulation Of Nucleic Acid-templated Transcription Cellular Nitrogen Compound Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Biosynthetic Process Multicellular Organismal Development Developmental Process Gene Expression Regulation Of Binding Regulation Of Gene Expression Anatomical Structure Development Cellular Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Epithelium Development Negative Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Embryo Development Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Wnt Signaling Pathway Negative Regulation Of Gene Expression Positive Regulation Of Nucleocytoplasmic Transport Embryo Development Ending In Birth Or Egg Hatching Regulation Of Signal Transduction Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Protein Metabolic Process Biosynthetic Process Regulation Of DNA Methylation Cell Cycle Somatic Stem Cell Maintenance Regulation Of Protein Binding Anatomical Structure Morphogenesis
Tagcloud ?		biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler	arrays attenuated cisplatin cochlea cochlear collectively custom downstream esr1 facilitates immunoblots insights interactomes jak1 machinery mediating modulating modulation nitration otoprotective ototoxicity partners pivotal player relaying stat stat3 trolox wistar
Tagcloud (Difference) ?		biosynthetic buildup cargo cathepsin correspond cycling endosomes explaining garp hydrolase hydrolases impairs intermediates lysosomes missorting mprs recycling relies retrograde shiga sorting swollen tgn tgn46 undegraded vesicles vps53 vps54 wobbler	arrays attenuated cisplatin cochlea cochlear collectively custom downstream esr1 facilitates immunoblots insights interactomes jak1 machinery mediating modulating modulation nitration otoprotective ototoxicity partners pivotal player relaying stat stat3 trolox wistar
Tagcloud (Intersection) ?