VPS52 and TSTD2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		VPS52	TSTD2
Description		VPS52 subunit of GARP complex	thiosulfate sulfurtransferase like domain containing 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	GARP Complex Endosome Golgi Apparatus Cytosol Endosome Membrane Membrane Trans-Golgi Network Membrane Perinuclear Region Of Cytoplasm Recycling Endosome Presynapse Postsynapse EARP Complex
	Molecular Function	Protein Binding Syntaxin Binding	Protein Binding
	Biological Process	Protein Targeting Golgi To Vacuole Transport Lysosomal Transport Ectodermal Cell Differentiation Protein Transport Endocytic Recycling Retrograde Transport, Endosome To Golgi Embryonic Ectodermal Digestive Tract Development Vesicle-mediated Cholesterol Transport
Pathways		Retrograde transport at the Trans-Golgi-Network
Drugs
Diseases
GWAS		Autism spectrum disorder or schizophrenia ( 28540026) Body mass index ( 26426971)
Interacting Genes		101 interacting genes: AAMP AIRIM ARNT2 ATP6V1D BYSL C1orf216 CABP5 CACNA1A CATSPERT CCDC102B CCDC13 CCDC146 CCDC185 CCDC187 CCDC33 CCDC57 CCHCR1 CDC20B CDC5L CDK18 CEP19 CFAP206 CWF19L2 DCX DDX6 DNAJC11 DTNB EPM2AIP1 FAM110A FAM161A FAM161B FAM184A FAM50B GEM GFM2 GOLGA1 GORASP2 GPKOW HAUS1 HDAC4 HEATR1 HGS HOXB5 JAKMIP2 KANK2 KIAA1217 KIF5B KIF9 KIFC3 KLC3 KLHL42 LMO4 LNX1 MAGEL2 MAPK3 METTL13 MFAP1 MRPL1 MRPL11 NDC80 NFKBIB NOP2 NR2C2AP OTUD6A PIMREG PKN3 PPP1R18 PRKAA1 PRKAA2 RAB4A RAB4B RABEP2 RUNX1T1 SCNM1 SH2D4A SMARCE1 STX11 TAB2 TBC1D1 TBC1D22B TCEANC TCP11L1 TEAD4 THAP11 TPM3 TRAF4 TRAF6 TSSK3 TSTD2 TXLNB TXN2 USP2 VEZF1 VPS28 VPS53 WASHC3 WTAP ZC2HC1C ZMAT2 ZNF417 ZNF587	33 interacting genes: AGR2 APC AURKA BLZF1 BUB1 CCND1 DCC EGFR FLCN IKZF1 IKZF3 INCA1 ISY1-RAB43 L3MBTL3 LHX4 MCC MEOX2 MLH3 MUTYH ODC1 PICK1 PTPRJ REL SMAD4 SSX2IP TCF4 TOX3 VPS52 ZBTB14 ZFPL1 ZNF438 ZNF774 ZRANB1
Entrez ID		6293	158427
HPRD ID		09142	16679
Ensembl ID		ENSG00000223501	ENSG00000136925
Uniprot IDs		A0A1U9X8S4 B3KMF7 B4DS44 Q4VXZ2 Q8N1B4	Q5T7W7
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Cytoskeleton Organelle Assembly Centrosome Microtubule Binding Microtubule-based Process Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Organelle Organization Organelle Disassembly Ciliary Basal Body Kinesin Complex Protein Localization To Lipid Droplet Protein Localization To Vacuole Microtubule Cytoskeleton Organization Protein Localization To Lysosome Negative Regulation Of Tubulin Deacetylation Negative Regulation Of Hepatocyte Apoptotic Process AMP-activated Protein Kinase Activity Insulin-responsive Compartment Centriole	Nucleus Nucleoplasm Regulation Of Primary Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Protein Serine/threonine Kinase Activity Sequence-specific DNA Binding DNA-binding Transcription Factor Activity Regulation Of Programmed Cell Death Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II DNA Binding Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Mesoderm Development DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Negative Regulation Of Cyclin-dependent Protein Kinase Activity Regulation Of Metabolic Process Regulation Of Apoptotic Process Negative Regulation Of Phosphate Metabolic Process Gamma-catenin Binding Response To UV-A Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Cardiocyte Differentiation Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Cellular Component Organization Regulation Of Wnt Signaling Pathway Negative Regulation Of Protein Kinase Activity Regulation Of Macromolecule Biosynthetic Process Regulation Of ERBB Signaling Pathway RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Kinase Activity Cellular Developmental Process Protein-containing Complex Binding Negative Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Protein Catabolic Process Developmental Process Digestive Tract Morphogenesis Regulation Of Cell Population Proliferation Negative Regulation Of Protein Metabolic Process Neuron Projection Guidance Axon Guidance Ruffle Membrane Heart Valve Development Beta-catenin Binding Animal Organ Development Negative Regulation Of Protein Phosphorylation Negative Regulation Of Metabolic Process
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