GDI2 and RAB11A

Number of citations of the paper that reports this interaction (PMID 10512627)
11

Data Source:
HPRD (in vitro)

		GDI2	RAB11A
Gene Name		GDP dissociation inhibitor 2	RAB11A, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Golgi Apparatus Cytosol Focal Adhesion Membrane Vesicle Extracellular Vesicular Exosome	Spindle Pole Mitochondrion Multivesicular Body Trans-Golgi Network Kinetochore Microtubule Cytosol Plasma Membrane Transport Vesicle Axon Cytoplasmic Vesicle Membrane Phagocytic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cleavage Furrow Protein Complex Phagocytic Vesicle Perinuclear Region Of Cytoplasm Recycling Endosome Recycling Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Rab GDP-dissociation Inhibitor Activity Rab GTPase Activator Activity Protein Binding Small GTPase Binding Poly(A) RNA Binding	GTPase Activity Protein Binding GTP Binding Microtubule Binding GDP Binding Syntaxin Binding Myosin V Binding
	Biological Process	Signal Transduction Small GTPase Mediated Signal Transduction Protein Transport Vesicle-mediated Transport Positive Regulation Of Rab GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Cytokinesis Renal Water Homeostasis Water Transport Intracellular Protein Transport Exocytosis Organelle Organization Mitotic Metaphase Plate Congression Positive Regulation Of Epithelial Cell Migration Regulation Of Multivesicular Body Size Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Vesicle-mediated Transport Astral Microtubule Organization Neuron Projection Development Melanosome Transport Rab Protein Signal Transduction Multivesicular Body Assembly Positive Regulation Of Axon Extension Regulation Of Long-term Neuronal Synaptic Plasticity Plasma Membrane To Endosome Transport Regulation Of Protein Transport Establishment Of Vesicle Localization Transmembrane Transport Regulation Of Vesicle-mediated Transport Establishment Of Protein Localization To Organelle Protein Localization To Plasma Membrane Establishment Of Protein Localization To Membrane Mitotic Spindle Assembly Exosomal Secretion
Pathways		Rho GTPase cycle Signaling by Rho GTPases	Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Vasopressin regulates renal water homeostasis via Aquaporins Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Aquaporin-mediated transport Anchoring of the basal body to the plasma membrane
Drugs
Diseases
GWAS		Osteosarcoma ( 23727862)
Protein-Protein Interactions		7 interactors: GLRA2 RAB11A RAB2A RAB4A RAB5A RAB8A RAB9A	28 interactors: CHMP1B CHMP3 DTNBP1 GDI2 IKBKG KAT2B MYO5A MYO5B OPTN PPP2R1A PPP2R1B PSEN1 PSEN2 PTGIR RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP4 RAB11FIP5 RAB3IL1 RABGGTB RCHY1 SEC13 STX4 TBXA2R TDP2 WDR44 YWHAG
Entrez ID		2665	8766
HPRD ID		02863	05715
Ensembl ID		ENSG00000057608	ENSG00000103769
Uniprot IDs		E7EU23 P50395 Q6IAT1	P62491
PDB IDs			1OIV 1OIW 1OIX 1YZK 2D7C 2GZD 2GZH 2HV8 4C4P
Enriched GO Terms of Interacting Partners?		Rab Protein Signal Transduction Ras Protein Signal Transduction Small GTPase Mediated Signal Transduction Regulation Of Vesicle-mediated Transport Intracellular Protein Transport Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Endosome Size Cellular Protein Localization Protein Transport Establishment Of Protein Localization Regulation Of Neuronal Synaptic Plasticity Intracellular Transport Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Cellular Localization Regulation Of Exocytosis Regulation Of Synaptic Plasticity Transport Establishment Of Vesicle Localization Endosomal Transport Vesicle Localization Signal Transduction Signaling Cell Communication Regulation Of Synaptic Transmission Establishment Of Organelle Localization Cellular Response To Stimulus Positive Regulation Of Exocytosis Organelle Localization Endomembrane System Organization Multivesicular Body Assembly Regulation Of Multivesicular Body Size Vesicle-mediated Transport Synaptic Vesicle Transport Multivesicular Body Organization Response To Stimulus Regulation Of Secretion Protein Localization To Plasma Membrane Golgi Vesicle Fusion To Target Membrane Receptor Internalization Involved In Canonical Wnt Signaling Pathway Mitotic Cell Cycle Exosomal Secretion Regulation Of Endocytosis Membrane Organization Plasma Membrane Organization Plasma Membrane To Endosome Transport Astral Microtubule Organization Regulation Of Cellular Localization Positive Regulation Of Secretion	Protein Transport Establishment Of Protein Localization Protein Localization Establishment Of Localization In Cell Cellular Localization Organelle Localization Vesicle-mediated Transport Establishment Of Organelle Localization Establishment Of Vesicle Localization Vesicle Localization Transport Exocytosis Regulation Of Signal Transduction Post-Golgi Vesicle-mediated Transport Membrane Organization Intracellular Transport Regulation Of Signaling Golgi Vesicle Transport Cell Death Death Insulin Secretion Secretion By Cell Insulin Secretion Involved In Cellular Response To Glucose Stimulus Regulation Of Synaptic Transmission Negative Regulation Of Protein Phosphorylation Regulation Of Catalytic Activity Regulated Secretory Pathway Regulation Of Synaptic Plasticity Regulation Of Body Fluid Levels Amyloid Precursor Protein Catabolic Process Cell-cell Signaling Peptide Hormone Secretion Secretion Peptide Secretion Positive Regulation Of Apoptotic Signaling Pathway Negative Regulation Of Phosphorylation Regulation Of Extrinsic Apoptotic Signaling Pathway Signaling Apoptotic Process Cell Cycle Cell Communication Negative Regulation Of Protein Kinase Activity Programmed Cell Death Positive Regulation Of Extrinsic Apoptotic Signaling Pathway Cell Cycle Process Negative Regulation Of Kinase Activity Hormone Secretion Regulation Of Protein Kinase Activity Beta-amyloid Metabolic Process Amyloid Precursor Protein Metabolic Process
Tagcloud ?		actb aldoa aldr catb catd catg co3 conceptus cst6 gd1b gda gsn hsp7c hsp90a hsp90a1 hspa8 idhc ifnt itraq phosphorylase pnp pnph ret4 rpb4 serpina31 tera timp2 ulf vcn	c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular
Tagcloud (Difference) ?		actb aldoa aldr catb catd catg co3 conceptus cst6 gd1b gda gsn hsp7c hsp90a hsp90a1 hspa8 idhc ifnt itraq phosphorylase pnp pnph ret4 rpb4 serpina31 tera timp2 ulf vcn	c2 compartments displays fip fip1 fip2 fip3 fip5 fips gtpases hela illumination integral lactc2 live membranes microscopy overlap overlapped overlapping pericentriolar phosphatidylserine probe ps recycling structured tubular
Tagcloud (Intersection) ?