PTPRF and IRS2

  • Number of citations of the paper that reports this interaction (PMID 15588985)
  • 37
  • Data Source:
  • HPRD (in vitro)

PTPRF

IRS2

Gene Name protein tyrosine phosphatase, receptor type, F insulin receptor substrate 2
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
Protein-Protein Interactions 23 interactors: BCAR1 CAV1 CDH1 CTNNB1 FRS2 FYN GALNT1 INSR IRS1 IRS2 JUP LCK NID1 PPFIA1 PPFIA2 PPFIA3 PRPF40A PTPRA PTPRD RET SKIL TRIO ZNF512B 38 interactors: ATP2A1 ATP2A2 BCL2L1 CRK EPOR FES GRB2 IGF1R IL4R INSR JAK1 JAK2 JAK3 MPL NTRK1 PIK3CA PIK3CD PIK3R1 PIK3R2 PIK3R3 PLCG1 PTPN11 PTPN6 PTPRF RPTOR SHC1 SIRT1 SOCS1 SOCS3 SOCS6 SOCS7 TYK2 UBTF YWHAB YWHAE YWHAG YWHAQ YWHAZ
Entrez ID 5792 8660
HPRD ID 01552 02878
Ensembl ID ENSG00000142949 ENSG00000185950
Uniprot IDs P10586 Q9P084 Q9Y4H2
PDB IDs 1LAR 2DJU 2DN7 2EDX 2EDY 2YD5 2YD8 3FQW 3FQX
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1r  abrogated  blue  bombesin  castration  cleavage  clonogenic  conditioned  contributions  docetaxel  endpoints  engineered  lncap  medium  ne  neuroendocrine  neuropeptides  neurotensin  paracrine  parp  pc3  phenomenon  principle  pthrp  secretions  talk  thoroughly  trypan  twofold 
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
Tagcloud (Difference) ?
1r  abrogated  blue  bombesin  castration  cleavage  clonogenic  conditioned  contributions  docetaxel  endpoints  engineered  lncap  medium  ne  neuroendocrine  neuropeptides  neurotensin  paracrine  parp  pc3  phenomenon  principle  pthrp  secretions  talk  thoroughly  trypan  twofold 
aacr  adaptive  adaptor  compensatory  conversely  cotargeting  dampen  dasatinib  ddr2  driven  emerged  gab1  harboring  igf1r  implicating  library  met  option  overlaying  panel  phosphoproteomics  py  rationale  res  rescued  rtk  scc  synergistic  weakly 
Tagcloud (Intersection) ?