PTPRF and INSR

  • Number of citations of the paper that reports this interaction (PMID 15588985)
  • 37
  • Data Source:
  • HPRD (in vivo, in vitro)

PTPRF

INSR

Gene Name protein tyrosine phosphatase, receptor type, F insulin receptor
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Amyotrophic lateral sclerosis (age of onset) ( 22959728)
Protein-Protein Interactions 23 interactors: BCAR1 CAV1 CDH1 CTNNB1 FRS2 FYN GALNT1 INSR IRS1 IRS2 JUP LCK NID1 PPFIA1 PPFIA2 PPFIA3 PRPF40A PTPRA PTPRD RET SKIL TRIO ZNF512B 77 interactors: ACP1 ADRB2 AHSG ARF1 ARHGAP26 CALM1 CALM2 CALM3 CAV1 CAV3 CBL CEACAM1 CRK CRKL CSK DOK1 DOK4 DOK5 ENPP1 FABP4 FRS2 GAB1 GNB2L1 GRB10 GRB14 GRB7 HRAS IGF1R IGF2 INS INSRR IRF7 IRS1 IRS2 JAK1 JAK2 KHDRBS1 KRT27 KRT31 MAD2L1 MAPK3 PIK3R1 PIK3R3 PLCG1 PRKCA PRKCD PTK2 PTPN1 PTPN11 PTPN12 PTPN2 PTPN6 PTPRC PTPRF RAF1 RASA1 SH2B1 SH2B2 SHC1 SMAD2 SNX1 SNX2 SNX4 SNX6 SOCS1 SOCS2 SOCS3 SOCS6 SORBS1 SRC STAT5A STAT5B SYNCRIP TEAD1 VAV1 VAV3 YWHAB
Entrez ID 5792 3643
HPRD ID 01552 00975
Ensembl ID ENSG00000142949 ENSG00000171105
Uniprot IDs P10586 P06213
PDB IDs 1LAR 2DJU 2DN7 2EDX 2EDY 2YD5 2YD8 1GAG 1I44 1IR3 1IRK 1P14 1RQQ 2AUH 2B4S 2DTG 2HR7 2Z8C 3BU3 3BU5 3BU6 3EKK 3EKN 3ETA 3LOH 3W11 3W12 3W13 3W14 4IBM
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1r  abrogated  blue  bombesin  castration  cleavage  clonogenic  conditioned  contributions  docetaxel  endpoints  engineered  lncap  medium  ne  neuroendocrine  neuropeptides  neurotensin  paracrine  parp  pc3  phenomenon  principle  pthrp  secretions  talk  thoroughly  trypan  twofold 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Difference) ?
1r  abrogated  blue  bombesin  castration  cleavage  clonogenic  conditioned  contributions  docetaxel  endpoints  engineered  lncap  medium  ne  neuroendocrine  neuropeptides  neurotensin  paracrine  parp  pc3  phenomenon  principle  pthrp  secretions  talk  thoroughly  trypan  twofold 
birthweight  cognate  curly  delays  determinant  dwarfing  edema  eliminated  embryogenesis  embryos  epidermis  generalized  hypoplasia  igf1r  igf2  igr1r  indistinguishable  manifested  mildly  muscles  nullizygotes  nullizygous  ossification  phenotypically  recognizes  retardation  solely  thin  xr 
Tagcloud (Intersection) ?