PTPRF and PTPRD

Number of citations of the paper that reports this interaction (PMID 12376545)
13

Data Source:
HPRD (in vivo)

		PTPRF	PTPRD
Gene Name		protein tyrosine phosphatase, receptor type, F	protein tyrosine phosphatase, receptor type, D
Image
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome	Integral Component Of Plasma Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Tyrosine Phosphatase Activity Transmembrane Receptor Protein Tyrosine Phosphatase Activity Heparin Binding Protein Complex Binding	Transmembrane Receptor Protein Tyrosine Phosphatase Activity Receptor Binding Protein Binding Cell Adhesion Molecule Binding
	Biological Process	Cell Adhesion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Migration Peptidyl-tyrosine Dephosphorylation Negative Regulation Of Receptor Binding	Protein Dephosphorylation Phosphate-containing Compound Metabolic Process Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Neuron Differentiation Peptidyl-tyrosine Dephosphorylation Positive Regulation Of Dendrite Morphogenesis Presynaptic Membrane Assembly
Pathways
Drugs
Diseases
GWAS		Amyotrophic lateral sclerosis (age of onset) ( 22959728)	Airflow obstruction ( 22837378) Attention deficit hyperactivity disorder and conduct disorder ( 18951430) Myopia (pathological) ( 23049088) Obesity-related traits ( 23251661) Palmitic acid (16:0) plasma levels ( 23362303) Partial epilepsies ( 20522523) Platelet aggregation ( 20526338) Restless legs syndrome ( 18660810 21779176) Temperament ( 22832960) Type 2 diabetes ( 21647700 20174558)
Protein-Protein Interactions		23 interactors: BCAR1 CAV1 CDH1 CTNNB1 FRS2 FYN GALNT1 INSR IRS1 IRS2 JUP LCK NID1 PPFIA1 PPFIA2 PPFIA3 PRPF40A PTPRA PTPRD RET SKIL TRIO ZNF512B	8 interactors: MTSS1 PPFIA1 PPFIA2 PPFIA3 PTPRA PTPRE PTPRF PTPRS
Entrez ID		5792	5789
HPRD ID		01552	03358
Ensembl ID		ENSG00000142949	ENSG00000153707
Uniprot IDs		P10586	F5GWT7 P23468 Q2HXI4 Q3KPI9 Q59H90
PDB IDs		1LAR 2DJU 2DN7 2EDX 2EDY 2YD5 2YD8	1X5Z 2DLH 2YD6 2YD7
Enriched GO Terms of Interacting Partners?		Enzyme Linked Receptor Protein Signaling Pathway Cellular Response To Organonitrogen Compound Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Cellular Response To Growth Factor Stimulus Response To Organonitrogen Compound Response To Growth Factor Cellular Response To Organic Substance Response To Peptide Hormone Response To Peptide Response To Organic Substance Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Cellular Response To Hormone Stimulus Cell Adhesion Insulin Receptor Signaling Pathway Response To Hormone Cellular Response To Indole-3-methanol Epidermal Growth Factor Receptor Signaling Pathway Cell Surface Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Apoptotic Process Cellular Response To Insulin Stimulus Signaling Regulation Of Cell Death System Development Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Cell Communication Locomotion Regulation Of Signaling Positive Regulation Of Signal Transduction Regulation Of Cellular Component Movement Phosphatidylinositol-mediated Signaling Positive Regulation Of Glycogen Biosynthetic Process Response To Insulin Multicellular Organismal Development Regulation Of Cell Proliferation Fibroblast Growth Factor Receptor Signaling Pathway Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Anatomical Structure Development Organ Development Cell Migration Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Cell Motility Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Signal Transduction	Glutamate Secretion Peptidyl-tyrosine Dephosphorylation Protein Dephosphorylation Acid Secretion Transmembrane Receptor Protein Tyrosine Phosphatase Signaling Pathway Dicarboxylic Acid Transport Neurotransmitter Secretion Dephosphorylation Regulation Of Neurotransmitter Levels Signaling Cell Communication Cell Adhesion Amino Acid Transport Neurotransmitter Transport Carboxylic Acid Transport Organic Acid Transport Enzyme Linked Receptor Protein Signaling Pathway Organic Anion Transport Secretion By Cell Adherens Junction Maintenance Synaptic Transmission Secretion Anion Transport Cell-matrix Adhesion Epithelial Cell Proliferation Involved In Renal Tubule Morphogenesis Nephron Tubule Epithelial Cell Differentiation Microspike Assembly Signal Transduction Cell-substrate Adhesion Negative Regulation Of Receptor Binding Cell-cell Signaling Negative Regulation Of Stress Fiber Assembly Negative Regulation Of Actin Filament Bundle Assembly Regulation Of Short-term Neuronal Synaptic Plasticity Negative Regulation Of Establishment Of Protein Localization To Plasma Membrane Magnesium Ion Homeostasis Corpus Callosum Development Cellular Response To Fluid Shear Stress Glomerulus Morphogenesis Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Protein Localization To Plasma Membrane Cellular Response To Stimulus Regulation Of Actin Filament-based Process Cellular Component Maintenance Phosphate-containing Compound Metabolic Process Movement Of Cell Or Subcellular Component Regulation Of Cytoskeleton Organization Regulation Of Mast Cell Activation Response To Fluid Shear Stress Negative Regulation Of Insulin Receptor Signaling Pathway
Tagcloud ?		1r abrogated blue bombesin castration cleavage clonogenic conditioned contributions docetaxel endpoints engineered lncap medium ne neuroendocrine neuropeptides neurotensin paracrine parp pc3 phenomenon principle pthrp secretions talk thoroughly trypan twofold	alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools
Tagcloud (Difference) ?		1r abrogated blue bombesin castration cleavage clonogenic conditioned contributions docetaxel endpoints engineered lncap medium ne neuroendocrine neuropeptides neurotensin paracrine parp pc3 phenomenon principle pthrp secretions talk thoroughly trypan twofold	alignment atlas bayesian brip1 bssv calculate called coverage enables evident false framework integrating lowered paired pgr precision rad51 rank read shared simulated simultaneous somatic ssv ssvs subtracting svs tools
Tagcloud (Intersection) ?