MTOR and TRAF6

  • Number of citations of the paper that reports this interaction (PMID 23911927)
  • 5
  • Data Source:
  • BioGRID (enzymatic study)

MTOR

TRAF6

Gene Name mechanistic target of rapamycin (serine/threonine kinase) TNF receptor-associated factor 6, E3 ubiquitin protein ligase
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 42 interactors: AKT1 AKT1S1 AMBRA1 BCL2L1 C7orf25 CDC37 CFP CLIP1 EIF3F EIF4EBP1 EIF4EBP2 FKBP1A FKBP8 GPHN GSK3B IRS1 MAF1 MLST8 PA2G4 PDPK1 PLD2 PPP2R2A PREX1 PRKAA1 PRKCA PRR5L RHEB RHEBL1 RICTOR RPS6KA1 RPS6KB1 RPS6KB2 RPTOR RRAGB RRAGD SEPT2 STAT3 TELO2 TERT TRAF6 UBQLN1 YWHAQ 144 interactors: ABL1 APP ATM ATP6V1E1 ATXN3 BECN1 BMPR1B CALCOCO2 CASP8 CAV1 CBL CD40 CYLD ECSIT EDA2R EDARADD FHL2 FYN GTF2I HIF1A HSPA4 IKBKG IL17RB IRAK1 IRAK2 IRAK3 IRAK4 IRF5 IRF7 IRF8 JAK2 KCNQ1 MALT1 MAP2K1 MAP2K6 MAP2K7 MAP3K11 MAP3K14 MAP3K3 MAP3K5 MAP3K7 MAP3K8 MAPK14 MAPK8 MAPT MAST2 MAVS MBP MCL1 MEOX2 MTOR NGFR NGFRAP1 NTRK1 NTRK2 NUMBL OTUB1 OTUB2 OTUD7B PELI3 PINK1 PLEKHF2 PLEKHO1 POLI PPP4C PRKCZ PSMB5 PSMC1 PSMC2 PSMC3 PSMD1 PSMD12 PSMD13 PSMD6 PSMD7 PTPN6 RIPK2 RNF114 SIGIRR SPHK1 SPOP SQSTM1 SRC STAMBP STRADB STUB1 SYK TAB1 TAB2 TAB3 TAX1BP1 TDP2 TGFBR1 TICAM1 TICAM2 TIFA TIRAP TLR3 TMEM189-UBE2V1 TNFAIP3 TNFRSF11A TNFRSF13B TNFRSF19 TNFSF11 TRAF1 TRAF2 TRAF3IP1 TRAF3IP2 TRAF4 TRAF5 TRAF7 TRAFD1 TRAM1 TRIM17 TRIM25 TRIM37 UBB UBE2D1 UBE2D2 UBE2D3 UBE2D4 UBE2E1 UBE2I UBE2L3 UBE2N UBE2V1 UBOX5 UEVLD USP1 USP15 USP2 USP21 USP39 USP4 USP5 USP7 VPS52 XIAP YBX1 YES1 ZFAND5 ZMYND11 ZNF675 ZRANB1
Entrez ID 2475 7189
HPRD ID 03134 03833
Ensembl ID ENSG00000198793
Uniprot IDs B4DZD5 P42345 Q9Y4K3
PDB IDs 1AUE 1FAP 1NSG 2FAP 2GAQ 2NPU 2RSE 3FAP 4DRH 4DRI 4DRJ 4FAP 4JSN 4JSP 4JSV 4JSX 4JT5 4JT6 1LB4 1LB5 1LB6 2ECI 2JMD 3HCS 3HCT 3HCU
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aib  aminoisobutyric  ars  arsenite  carrier  hormonal  hs  hyperthermic  instigate  involve  k2  km  l6  map  mapkap  maximally  metabolisable  p42  p44  phosphoinositide  pi3k  rapamycin  sapk2  sb  stresses  transport  transporter  vmax  whilst  wortmannin 
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  jak3  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf2  traf3  traf5  transduction 
Tagcloud (Difference) ?
aib  aminoisobutyric  ars  arsenite  carrier  hormonal  hs  hyperthermic  instigate  involve  k2  km  l6  map  mapkap  maximally  metabolisable  p42  p44  phosphoinositide  pi3k  rapamycin  sapk2  sb  stresses  transport  transporter  vmax  whilst  wortmannin 
adhesion  affinity  bind  cd40  cd40ct  cytoplasmic  dispensable  dominantly  extensive  icam  ikappabalpha  implicated  incapable  intercellular  jak3  kappab  mediators  molecule  much  mutants  necrosis  residues  strongly  tail  traf2  traf3  traf5  transduction 
Tagcloud (Intersection) ?