MTOR and RHEB

  • Number of citations of the paper that reports this interaction (PMID 15854902)
  • 168
  • Data Source:
  • BioGRID (affinity chromatography technology, affinity chromatography technology)
  • HPRD (in vitro, in vivo)

MTOR

RHEB

Gene Name mechanistic target of rapamycin (serine/threonine kinase) Ras homolog enriched in brain
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 42 interactors: AKT1 AKT1S1 AMBRA1 BCL2L1 C7orf25 CDC37 CFP CLIP1 EIF3F EIF4EBP1 EIF4EBP2 FKBP1A FKBP8 GPHN GSK3B IRS1 MAF1 MLST8 PA2G4 PDPK1 PLD2 PPP2R2A PREX1 PRKAA1 PRKCA PRR5L RHEB RHEBL1 RICTOR RPS6KA1 RPS6KB1 RPS6KB2 RPTOR RRAGB RRAGD SEPT2 STAT3 TELO2 TERT TRAF6 UBQLN1 YWHAQ 22 interactors: A2M APOE ARIH2 ATM ATR BNIP3 BNIP3L BRAF ECSIT FKBP8 MTOR NCAM1 PDE6D PLD1 PSEN1 PSEN2 RABAC1 RAF1 RPS6KB1 RPTOR TSC1 TSC2
Entrez ID 2475 6009
HPRD ID 03134 03188
Ensembl ID ENSG00000198793 ENSG00000106615
Uniprot IDs B4DZD5 P42345 Q15382
PDB IDs 1AUE 1FAP 1NSG 2FAP 2GAQ 2NPU 2RSE 3FAP 4DRH 4DRI 4DRJ 4FAP 4JSN 4JSP 4JSV 4JSX 4JT5 4JT6 1XTQ 1XTR 1XTS 3SEA 3T5G
Enriched GO Terms of Interacting Partners?
Tagcloud ?
aib  aminoisobutyric  ars  arsenite  carrier  hormonal  hs  hyperthermic  instigate  involve  k2  km  l6  map  mapkap  maximally  metabolisable  p42  p44  phosphoinositide  pi3k  rapamycin  sapk2  sb  stresses  transport  transporter  vmax  whilst  wortmannin 
abovementioned  altogether  amls  angiomyolipomas  carry  chronically  comparative  deficient  diminished  farnesylthiosalicylic  fts  indeed  irf7  lam  lymphangioleiomyomatosis  mimicked  mtorc1  neoplasms  pathologies  phenomena  rapamycin  salirasib  sirolimus  sporadic  trans  tsc  tsc2  tuberous  yielded 
Tagcloud (Difference) ?
aib  aminoisobutyric  ars  arsenite  carrier  hormonal  hs  hyperthermic  instigate  involve  k2  km  l6  map  mapkap  maximally  metabolisable  p42  p44  phosphoinositide  pi3k  sapk2  sb  stresses  transport  transporter  vmax  whilst  wortmannin 
abovementioned  altogether  amls  angiomyolipomas  carry  chronically  comparative  deficient  diminished  farnesylthiosalicylic  fts  indeed  irf7  lam  lymphangioleiomyomatosis  mimicked  mtorc1  neoplasms  pathologies  phenomena  salirasib  sirolimus  sporadic  trans  tsc  tsc2  tuberous  yielded 
Tagcloud (Intersection) ?
rapamycin