PTK2 and HES1

  • Number of citations of the paper that reports this interaction (PMID 21900206)
  • 27
  • Data Source:
  • BioGRID (two hybrid)

PTK2

HES1

Gene Name protein tyrosine kinase 2 hes family bHLH transcription factor 1
Image No pdb structure
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to interferon beta therapy ( 21502966)
Protein-Protein Interactions 104 interactors: ACTN1 APP ARHGAP26 ASAP1 ATG12 BBS10 BCAR1 BIN1 BMX CCR5 CD47 CD79B CIB1 CRK CSK CSPG4 CXCR4 DCC DDX39A DEF6 DLGAP3 DNM2 EEF1G EFS EGFR EPHA2 EPHB2 EPS8L2 ERBB2 ERBB3 EZR F13A1 FBP1 FGR FLT1 FLT4 FYN GIT1 GRB2 GRB7 GSK3B GZMB HES1 IGHM INSR IRS1 ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 JAK2 KCNMA1 LCK LPXN LYN MAPK8IP3 MDM2 MICAL1 NACAD NASP NCK1 NCK2 NEDD8 NEDD9 NEO1 PDGFRB PIAS1 PIK3R1 PKD1 PLCG1 PPP1CB PTK2B PTPN11 PTPN12 PTPRH PXN RAC1 RB1CC1 RET RIPK1 ROCK1 SAE1 SELE SHC1 SOCS2 SOCS3 SORBS1 SRC SRPK1 STAT1 SYK TGFB1I1 TLN1 TNFRSF1A TNS1 TP53 TRIO TRIP6 TSC2 VCL YES1 ZNF331 33 interactors: APCS APH1A ASGR2 CSNK1E FANCA FANCE FANCF FANCG FANCL FHL1 FOXG1 GAPDH HDAC6 HES6 HEY2 HMGB1 HMGCL ID1 ID2 ID3 ID4 JAK2 LTBR NR4A1 NUDT3 PRKCA PTK2 SIRT1 STAT3 TLE1 TLE2 UBQLN1 YWHAB
Entrez ID 5747 3280
HPRD ID 02859 00770
Ensembl ID ENSG00000169398 ENSG00000114315
Uniprot IDs E7ESA6 Q05397 Q59GM6 Q658W2 Q14469
PDB IDs 1K04 1K05 1MP8 1OW6 1OW7 1OW8 2ETM 2IJM 2RA7 3B71 3BZ3 3PXK 3S9O 4EBV 4EBW 4GU6 4GU9 4I4E 4I4F 4K8A 4K9Y 4KAB 4KAO
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acta  biochem  brindle  critchley  davies  fefpppptde  flexneri  icsa  immunofluoresence  microinjected  microinjection  nonmuscle  oligoproline  pdfpppppdl  profilin  reorganizes  rocket  sasakawa  shigella  submicromolar  suzuki  trailing  unmasked  unmasking  unmasks  usurping  vasp  vinc  vinculin 
alterations  anatomic  astrocytoma  astrocytomas  biology  braf  grade  hey1  hey2  implicated  inhibiting  interference  much  needed  neoplastic  notch  notch1  notch2  overexpressed  pa  pas  pediatric  pilocytic  res186  res259  secretase  tumorigenesis  variable  viable 
Tagcloud (Difference) ?
acta  biochem  brindle  critchley  davies  fefpppptde  flexneri  icsa  immunofluoresence  microinjected  microinjection  nonmuscle  oligoproline  pdfpppppdl  profilin  reorganizes  rocket  sasakawa  shigella  submicromolar  suzuki  trailing  unmasked  unmasking  unmasks  usurping  vasp  vinc  vinculin 
alterations  anatomic  astrocytoma  astrocytomas  biology  braf  grade  hey1  hey2  implicated  inhibiting  interference  much  needed  neoplastic  notch  notch1  notch2  overexpressed  pa  pas  pediatric  pilocytic  res186  res259  secretase  tumorigenesis  variable  viable 
Tagcloud (Intersection) ?