PTK2 and NEDD8

  • Number of citations of the paper that reports this interaction (PMID 16620772)
  • 10
  • Data Source:
  • BioGRID (affinity chromatography technology)
  • HPRD (in vivo)

PTK2

NEDD8

Gene Name protein tyrosine kinase 2 neural precursor cell expressed, developmentally down-regulated 8
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
  • Response to interferon beta therapy ( 21502966)
Protein-Protein Interactions 104 interactors: ACTN1 APP ARHGAP26 ASAP1 ATG12 BBS10 BCAR1 BIN1 BMX CCR5 CD47 CD79B CIB1 CRK CSK CSPG4 CXCR4 DCC DDX39A DEF6 DLGAP3 DNM2 EEF1G EFS EGFR EPHA2 EPHB2 EPS8L2 ERBB2 ERBB3 EZR F13A1 FBP1 FGR FLT1 FLT4 FYN GIT1 GRB2 GRB7 GSK3B GZMB HES1 IGHM INSR IRS1 ITGAV ITGB1 ITGB2 ITGB3 ITGB4 ITGB5 JAK2 KCNMA1 LCK LPXN LYN MAPK8IP3 MDM2 MICAL1 NACAD NASP NCK1 NCK2 NEDD8 NEDD9 NEO1 PDGFRB PIAS1 PIK3R1 PKD1 PLCG1 PPP1CB PTK2B PTPN11 PTPN12 PTPRH PXN RAC1 RB1CC1 RET RIPK1 ROCK1 SAE1 SELE SHC1 SOCS2 SOCS3 SORBS1 SRC SRPK1 STAT1 SYK TGFB1I1 TLN1 TNFRSF1A TNS1 TP53 TRIO TRIP6 TSC2 VCL YES1 ZNF331 34 interactors: AHR ANK1 ARIH1 ARIH2 CDC34 COPS5 COPS6 CTRC CUL1 CUL2 CUL3 CUL4B CUL5 DCUN1D1 DNMT3B NAE1 NPLOC4 NUB1 PARP1 PSMD4 PTK2 RPL11 SENP8 SMURF1 TP53 UBA2 UBA3 UBE2F UBE2K UBE2M UBXN7 UCHL1 UCHL3 UFD1L
Entrez ID 5747 4738
HPRD ID 02859 04412
Ensembl ID ENSG00000169398 ENSG00000129559
Uniprot IDs E7ESA6 Q05397 Q59GM6 Q658W2 Q15843
PDB IDs 1K04 1K05 1MP8 1OW6 1OW7 1OW8 2ETM 2IJM 2RA7 3B71 3BZ3 3PXK 3S9O 4EBV 4EBW 4GU6 4GU9 4I4E 4I4F 4K8A 4K9Y 4KAB 4KAO 1NDD 1R4M 1R4N 1XT9 2BKR 2KO3 2NVU 3DBH 3DBL 3DBR 3DQV 3GZN 4F8C 4FBJ 4HCP
Enriched GO Terms of Interacting Partners?
Tagcloud ?
acta  biochem  brindle  critchley  davies  fefpppptde  flexneri  icsa  immunofluoresence  microinjected  microinjection  nonmuscle  oligoproline  pdfpppppdl  profilin  reorganizes  rocket  sasakawa  shigella  submicromolar  suzuki  trailing  unmasked  unmasking  unmasks  usurping  vasp  vinc  vinculin 
activate  activates  activating  analyze  app  appbp1  covalently  cullin  discuss  downregulates  driven  existing  gradual  gradually  hypothesize  insights  integrity  investigation  ligases  lost  modifies  neddylation  precursor  protects  reverse  slow  switches  turnover  ubiquitin 
Tagcloud (Difference) ?
acta  biochem  brindle  critchley  davies  fefpppptde  flexneri  icsa  immunofluoresence  microinjected  microinjection  nonmuscle  oligoproline  pdfpppppdl  profilin  reorganizes  rocket  sasakawa  shigella  submicromolar  suzuki  trailing  unmasked  unmasking  unmasks  usurping  vasp  vinc  vinculin 
activate  activates  activating  analyze  app  appbp1  covalently  cullin  discuss  downregulates  driven  existing  gradual  gradually  hypothesize  insights  integrity  investigation  ligases  lost  modifies  neddylation  precursor  protects  reverse  slow  switches  turnover  ubiquitin 
Tagcloud (Intersection) ?