CBX8 and KIFC3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		CBX8	KIFC3
Gene Name		chromobox homolog 8	kinesin family member C3
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Golgi Apparatus Centrosome Kinesin Complex Microtubule Zonula Adherens Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome
	Molecular Function	Single-stranded RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Methylated Histone Binding	Microtubule Motor Activity ATP Binding Microtubule Binding ATPase Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Histone Ubiquitination	Microtubule-based Movement Golgi Organization Visual Perception Metabolic Process Zonula Adherens Maintenance Epithelial Cell-cell Adhesion
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: BMI1 CALCOCO2 CCDC136 CCDC57 EEF1G FSD2 GOLGA2 GPRASP2 HAP1 HIST3H3 HMBOX1 IKZF1 KAT5 KAT7 KCTD9 KIFC3 KRT40 LZTS2 MID2 MLLT1 MLLT3 MTUS2 PAXIP1 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC2 PNMA2 RING1 RNF2 RPGRIP1 SETDB1 SOX5 TFCP2 TRAF2 TSGA10 UNC119 USP11 USP7 ZBTB14	91 interactors: ABI2 AES ANXA13 APP ARNT2 ATF2 BCL6 C1orf109 CBX8 CCDC102B CCDC136 CCDC28A CCDC33 CCDC67 CDK18 CDR2 CEP170P1 CEP55 CEP57L1 CLIP4 CREB5 CYTH4 DCTN2 DCX DTNBP1 ESRRG FAM124A FANCL FCHSD2 GMCL1 GOLGA2 GORASP2 HAUS1 HSBP1 ICA1L ITGB3BP KANSL1 KDM1A KRT15 KRT19 KRT31 KRT40 KRT5 KRT6A KRT6B KRT6C LENG1 LIN37 LZTS2 MCM7 MED4 MFAP1 MID2 MOS NDEL1 NECAB2 NEDD4 NEDD4L NEFL NUP62 PHC2 PRKAA2 PSMB1 RAD51D RSPH14 SCEL SIAH1 SMARCE1 SNAP29 SOX30 SOX5 SPERT SVIL SYCE1 TCEANC TNIP1 TPM3 TRAF2 TRIM23 TRIM27 TRIM41 TRIM54 TSG101 TSR2 USP2 ZBTB8A ZGPAT ZNF180 ZNF20 ZNF572 ZNF655
Entrez ID		57332	3801
HPRD ID		13006	05171
Ensembl ID			ENSG00000140859
Uniprot IDs		Q9HC52	B7Z484 B7Z896 F5H4I9 Q9BVG8
PDB IDs		3I91	2H58
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Histone Modification Chromatin Modification Chromosome Organization Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Ubiquitination Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Histone H2A Monoubiquitination Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Histone H2A Ubiquitination Peptidyl-lysine Modification Regulation Of Metabolic Process Histone Monoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Organelle Organization Histone Acetylation Protein Modification By Small Protein Conjugation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Monoubiquitination Anterior/posterior Pattern Specification Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Segment Specification Cellular Protein Modification Process Cellular Response To Reactive Oxygen Species	Cell Cycle Organelle Organization Cell Cycle Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Regulation Of Gene Expression Regulation Of RNA Metabolic Process Mitotic Cell Cycle RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Gene Expression Cytoskeleton Organization Mitotic Cell Cycle Process RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Developmental Process Axon Cargo Transport Microtubule-based Process Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Gene Expression Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Macromolecule Biosynthetic Process Cellular Process Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Protein Binding Regulation Of Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Protein K63-linked Ubiquitination Retrograde Axon Cargo Transport Protein Polyubiquitination Anatomical Structure Development Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Chromosome Organization Protein Monoubiquitination Cellular Nitrogen Compound Metabolic Process Reproduction Heterocycle Metabolic Process Microtubule Cytoskeleton Organization Cellular Aromatic Compound Metabolic Process
Tagcloud ?		aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kinesin kinesins mll1
Tagcloud (Difference) ?		aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western	18b 20b 5b ancca atad2 bromodomain concerted coregulator deregulation drives impeded kif10 kif11 kif15 kif18a kif1a kif1c kif20a kif21 kif23 kif24 kif25 kif4a kif5a kif7 kifc1 kinesin kinesins mll1
Tagcloud (Intersection) ?