CBX8 and PCGF5

Number of citations of the paper that reports this interaction (PMID 21282530)
11

Data Source:
BioGRID (affinity chromatography technology, pull down)

		CBX8	PCGF5
Gene Name		chromobox homolog 8	polycomb group ring finger 5
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm PcG Protein Complex PRC1 Complex	Nucleus Nucleolus Centrosome PcG Protein Complex
	Molecular Function	Single-stranded RNA Binding Ubiquitin-protein Transferase Activity Protein Binding Methylated Histone Binding	Protein Binding Zinc Ion Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Histone Ubiquitination	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS
Protein-Protein Interactions		42 interactors: BMI1 CALCOCO2 CCDC136 CCDC57 EEF1G FSD2 GOLGA2 GPRASP2 HAP1 HIST3H3 HMBOX1 IKZF1 KAT5 KAT7 KCTD9 KIFC3 KRT40 LZTS2 MID2 MLLT1 MLLT3 MTUS2 PAXIP1 PCGF1 PCGF2 PCGF3 PCGF5 PCGF6 PHC2 PNMA2 RING1 RNF2 RPGRIP1 SETDB1 SOX5 TFCP2 TRAF2 TSGA10 UNC119 USP11 USP7 ZBTB14	11 interactors: BCOR CBX6 CBX7 CBX8 PCGF1 PHC2 PRMT6 RING1 RNF2 TRAF2 TRIM8
Entrez ID		57332	84333
HPRD ID		13006	17825
Ensembl ID			ENSG00000180628
Uniprot IDs		Q9HC52	Q86SE9
PDB IDs		3I91
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process Histone Modification Chromatin Modification Chromosome Organization Regulation Of Transcription, DNA-templated Gene Expression Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Chromatin Organization Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Histone Ubiquitination Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Biosynthetic Process Histone H2A Monoubiquitination Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Histone H2A Ubiquitination Peptidyl-lysine Modification Regulation Of Metabolic Process Histone Monoubiquitination Negative Regulation Of Transcription From RNA Polymerase II Promoter Protein Ubiquitination Organelle Organization Histone Acetylation Protein Modification By Small Protein Conjugation Internal Peptidyl-lysine Acetylation Peptidyl-lysine Acetylation Internal Protein Amino Acid Acetylation Protein Monoubiquitination Anterior/posterior Pattern Specification Protein Acetylation Regulation Of Transcription From RNA Polymerase II Promoter Cellular Metabolic Process Segment Specification Cellular Protein Modification Process Cellular Response To Reactive Oxygen Species	Histone Ubiquitination Histone H2A Monoubiquitination Histone H2A Ubiquitination Chromatin Modification Chromatin Organization Histone Monoubiquitination Protein Ubiquitination Chromosome Organization Protein Modification By Small Protein Conjugation Protein Monoubiquitination Negative Regulation Of RNA Biosynthetic Process Histone Modification Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Regulation Of RNA Metabolic Process Transcription, DNA-templated Regulation Of Gene Expression RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Organelle Organization RNA Metabolic Process Cellular Protein Modification Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Metabolic Process Cellular Protein Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Histone H3-K36 Methylation Nitrogen Compound Metabolic Process Protein Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Histone H3-R2 Methylation Negative Regulation Of Tooth Mineralization Histone H2A-K119 Monoubiquitination Pattern Specification Process Axis Specification Cellular Metabolic Process Positive Regulation Of NF-kappaB Transcription Factor Activity
Tagcloud ?		aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western	actg1 adaptin bacterium caenorhabditis cap1 chaffeensis colocalized cored cotransformation cox2 ehrlichia evading gga1 host igl igll1 morulae obligately phagocytes reconstitute reprogram survives tr tropism trp120 trp47 trps unc unc13d
Tagcloud (Difference) ?		aims approaches beings blotting causes chromobox colon conclude cultured express facilitating hct116 homolog igf1 igf1r knockdown leading line overexpression pathogenesis proliferation promote promoting real reports rt silencing unclear western	actg1 adaptin bacterium caenorhabditis cap1 chaffeensis colocalized cored cotransformation cox2 ehrlichia evading gga1 host igl igll1 morulae obligately phagocytes reconstitute reprogram survives tr tropism trp120 trp47 trps unc unc13d
Tagcloud (Intersection) ?